Hormones and their Signaling Pathways
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Questions and Answers

Which hormones act through the cAMP system? (Select all that apply)

  • Insulin
  • Prolactin
  • Angiotensin-II (correct)
  • Vasopressin (correct)
  • Which hormone is primarily associated with the PLC (Phospholipase C) system?

  • Catecholamines (correct)
  • TSH
  • GHRH
  • Glucagon
  • Which hormones use the cGMP system? (Select all that apply)

  • ANP (correct)
  • Prolactin
  • Growth Hormone
  • Nitric Oxide (correct)
  • Which of the following hormones uses tyrosine kinase receptors? (Select all that apply)

    <p>Erythropoietin</p> Signup and view all the answers

    What system do gastrointestinal polypeptides activate?

    <p>cGMP system</p> Signup and view all the answers

    ____ is known to activate intracellular cGMP.

    <p>Nitric Oxide</p> Signup and view all the answers

    Study Notes

    Hormones and their Signaling Pathways

    • cAMP System:
      • Angiotensin-II (vascular smooth muscle): Activates both cAMP and PLC systems.
      • PGE1 (Prostaglandin E1): Activates cAMP.
      • Catecholamines (α2, β receptors): Activates cAMP via β receptors and PLC via α2 receptors.
      • Vasopressin (V2 receptor): Activates cAMP.
      • FSH (Follicle Stimulating Hormone), LH (Luteinizing Hormone), ACTH (Adrenocorticotropic Hormone), TSH (Thyroid Stimulating Hormone), HCG (Human Chorionic Gonadotropin), PTH (Parathyroid Hormone), Calcitonin, and Somatostatin: All activate cAMP.
      • Secretin and Glucagon: Activate cAMP.
      • Muscarinic 2 and 4 receptors: Activate cAMP.
    • PLC (Phospholipase C) System:
      • Angiotensin-II (vascular smooth muscle): Activates PLC.
      • Catecholamines (α1 receptors): Activates PLC.
      • Vasopressin (V1 receptor), Oxytocin, GHRH (Growth Hormone-Releasing Hormone), TRH (Thyrotropin-Releasing Hormone), GnRH (Gonadotropin-Releasing Hormone), and Muscarinic 1, 3, and 5 receptors: All activate PLC.
    • cGMP System:
      • ANP (Atrial Natriuretic Peptide): Activates cGMP.
      • Gastrointestinal polypeptides: Contribute to trans-cellular cGMP activation.
      • Nitric Oxide (NO): Activates intracellular cGMP.
    • Tyrosine Kinase Receptors:
      • Insulin, IGF-1 (Insulin-like Growth Factor 1), EGF (Epidermal Growth Factor), PDGF (Platelet-Derived Growth Factor), Macrophage-CSF (Macrophage Colony-Stimulating Factor), GH (Growth Hormone), Prolactin, and Erythropoietin: All utilize tyrosine kinase receptors for signaling.

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    Description

    This quiz covers the cAMP and PLC signaling pathways associated with various hormones such as Angiotensin-II, catecholamines, and more. Test your knowledge on how these hormones activate different signaling systems in the body.

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