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Questions and Answers
Which hormones act through the cAMP system? (Select all that apply)
Which hormone is primarily associated with the PLC (Phospholipase C) system?
Which hormones use the cGMP system? (Select all that apply)
Which of the following hormones uses tyrosine kinase receptors? (Select all that apply)
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What system do gastrointestinal polypeptides activate?
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____ is known to activate intracellular cGMP.
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Study Notes
Hormones and their Signaling Pathways
-
cAMP System:
- Angiotensin-II (vascular smooth muscle): Activates both cAMP and PLC systems.
- PGE1 (Prostaglandin E1): Activates cAMP.
- Catecholamines (α2, β receptors): Activates cAMP via β receptors and PLC via α2 receptors.
- Vasopressin (V2 receptor): Activates cAMP.
- FSH (Follicle Stimulating Hormone), LH (Luteinizing Hormone), ACTH (Adrenocorticotropic Hormone), TSH (Thyroid Stimulating Hormone), HCG (Human Chorionic Gonadotropin), PTH (Parathyroid Hormone), Calcitonin, and Somatostatin: All activate cAMP.
- Secretin and Glucagon: Activate cAMP.
- Muscarinic 2 and 4 receptors: Activate cAMP.
-
PLC (Phospholipase C) System:
- Angiotensin-II (vascular smooth muscle): Activates PLC.
- Catecholamines (α1 receptors): Activates PLC.
- Vasopressin (V1 receptor), Oxytocin, GHRH (Growth Hormone-Releasing Hormone), TRH (Thyrotropin-Releasing Hormone), GnRH (Gonadotropin-Releasing Hormone), and Muscarinic 1, 3, and 5 receptors: All activate PLC.
-
cGMP System:
- ANP (Atrial Natriuretic Peptide): Activates cGMP.
- Gastrointestinal polypeptides: Contribute to trans-cellular cGMP activation.
- Nitric Oxide (NO): Activates intracellular cGMP.
-
Tyrosine Kinase Receptors:
- Insulin, IGF-1 (Insulin-like Growth Factor 1), EGF (Epidermal Growth Factor), PDGF (Platelet-Derived Growth Factor), Macrophage-CSF (Macrophage Colony-Stimulating Factor), GH (Growth Hormone), Prolactin, and Erythropoietin: All utilize tyrosine kinase receptors for signaling.
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Description
This quiz covers the cAMP and PLC signaling pathways associated with various hormones such as Angiotensin-II, catecholamines, and more. Test your knowledge on how these hormones activate different signaling systems in the body.
