Hormones and Kidney Functions VPHY 2 LECTURE

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What is the primary role of aldosterone in the human body?

Promoting Na+ and water retention, and lowering plasma K+ concentration

Which hormone is directly responsible for stimulating the release of aldosterone in response to decreased blood pressure?


Which cells in the kidney nephron are primarily targeted by aldosterone to promote Na+ and water retention?

Principal cells of the distal tubule and collecting duct

Which of the following is NOT a member of the mineralocorticoid class?


Which of the following factors has only a minor role in regulating aldosterone production?


Atrial natriuretic peptide (ANP) increases pressure in the glomerular capillaries, leading to a decrease in the glomerular filtration rate (GFR).


ANP inhibits renin secretion, thus suppressing the renin-angiotensin-aldosterone system.


A decrease in sodium reabsorption in the distal convoluted tubule and cortical collecting duct of the nephron leads to decreased excretion of sodium and water.


Arginine vasopressin (AVP) primarily functions to promote water retention and vasodilation.


Reduction in aldosterone secretion by the adrenal cortex leads to decreased sodium reabsorption in the distal tubule and cortical collecting duct.


Explore the topic of the renin–angiotensin system (RAS) and its role in regulating blood pressure and water balance in the kidneys. Learn about the secretion of renin, conversion of angiotensinogen, and the functions of angiotensin I. Prepared by VAMorillo.

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