Hormones and Growth Hormone Biosynthesis

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Where are the mRNAs for IGF-I and IGF-II found?

In the brain

In the liver (correct)

In the kidneys

In the heart

What stimulates the secretion of IGF-I after birth?

IGF-II

Thyroid hormone

Insulin

Growth hormone (correct)

What is the pattern of IGF-I concentration in plasma?

Remains constant throughout life

Increases during old age and declines during childhood

Declines during childhood and increases in old age

Rises during childhood and peaks at puberty, then declines (correct)

What is the main role of IGF-II during fetal development?

Growth of the fetus before birth Signup and view all the answers

What happens in human fetuses with overexpressed IGF-II?

Several organs, especially the tongue, muscles, kidneys, heart, and liver, develop out of proportion to the rest of the body Signup and view all the answers

In adults, where is the gene for IGF-II expressed?

Only in the choroid plexus and meninges Signup and view all the answers

What is the effect of IGF-I on growth?

It has pronounced growth-stimulating activity Signup and view all the answers

What is the relationship between IGF-II and growth hormone?

IGF-II is largely independent of growth hormone Signup and view all the answers

When is IGF-I secretion independent of growth hormone?

Only before birth Signup and view all the answers

What is the pattern of IGF-I concentration in old age?

It declines Signup and view all the answers

Hormones and Growth Hormone Biosynthesis

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Questions and Answers

Where are the mRNAs for IGF-I and IGF-II found?

What stimulates the secretion of IGF-I after birth?

What is the pattern of IGF-I concentration in plasma?

What is the main role of IGF-II during fetal development?

What happens in human fetuses with overexpressed IGF-II?

In adults, where is the gene for IGF-II expressed?

What is the effect of IGF-I on growth?

What is the relationship between IGF-II and growth hormone?

When is IGF-I secretion independent of growth hormone?

What is the pattern of IGF-I concentration in old age?

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