Hormones and Growth Hormone Biosynthesis
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Questions and Answers

Where are the mRNAs for IGF-I and IGF-II found?

  • In the brain
  • In the liver (correct)
  • In the kidneys
  • In the heart

What stimulates the secretion of IGF-I after birth?

  • IGF-II
  • Thyroid hormone
  • Insulin
  • Growth hormone (correct)

What is the pattern of IGF-I concentration in plasma?

  • Remains constant throughout life
  • Increases during old age and declines during childhood
  • Declines during childhood and increases in old age
  • Rises during childhood and peaks at puberty, then declines (correct)

What is the main role of IGF-II during fetal development?

<p>Growth of the fetus before birth (C)</p> Signup and view all the answers

What happens in human fetuses with overexpressed IGF-II?

<p>Several organs, especially the tongue, muscles, kidneys, heart, and liver, develop out of proportion to the rest of the body (B)</p> Signup and view all the answers

In adults, where is the gene for IGF-II expressed?

<p>Only in the choroid plexus and meninges (C)</p> Signup and view all the answers

What is the effect of IGF-I on growth?

<p>It has pronounced growth-stimulating activity (D)</p> Signup and view all the answers

What is the relationship between IGF-II and growth hormone?

<p>IGF-II is largely independent of growth hormone (C)</p> Signup and view all the answers

When is IGF-I secretion independent of growth hormone?

<p>Only before birth (C)</p> Signup and view all the answers

What is the pattern of IGF-I concentration in old age?

<p>It declines (B)</p> Signup and view all the answers

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