10 Questions
What is the percentage of cases of Cushing's syndrome caused by ectopic ACTH secretion by non-pituitary tumors?
10-15%
What is the result of excess aldosterone secretion in the body?
Hypertension with hypokalemia
What is the term for the phenomenon where normal individuals excrete excess sodium when given excess aldosterone?
Escape Phenomenon
What is the cause of 65% of Primary Hyperaldosteronism cases?
Small tumor arising from the zona glomerulosa
What is the result of loss of feedback inhibition in Nelson's Syndrome?
Intense skin pigmentation
What is the laboratory finding in patients with Adrenal Adenoma, Carcinoma, and Cortical Hyperplasia?
Increased cortisol levels and decreased ACTH levels
What is the percentage of cases of Primary Hyperaldosteronism caused by hyperplastic adrenal cortices?
30%
What is the consequence of excess aldosterone secretion on potassium levels?
Hypokalemia
What is the term for the condition characterized by hypertension with hypokalemia due to excess aldosterone secretion?
Primary Hyperaldosteronism
What is the cause of 10-15% of cases of Cushing's syndrome?
Ectopic ACTH secretion by non-pituitary tumors
Learn about the process of hormone synthesis and release, from the Rough Endoplasmic Reticulum to the Golgi Apparatus and finally to the cell membrane. Understand the role of Ca++ and cAMP in hormone release and the importance of gap junctions and small pores.
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