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Questions and Answers
What is the organizational/activational hypothesis primarily used to explain?
What is the organizational/activational hypothesis primarily used to explain?
Which statement accurately describes the difference between organizational and activational effects of hormones?
Which statement accurately describes the difference between organizational and activational effects of hormones?
Which example BEST demonstrates an activational effect of hormones?
Which example BEST demonstrates an activational effect of hormones?
Which disorder of sex development (DSD) is mentioned in the text?
Which disorder of sex development (DSD) is mentioned in the text?
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What is the primary advantage of studying DSDs in research?
What is the primary advantage of studying DSDs in research?
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What is the key difference between chromosomal sex and sexual differentiation?
What is the key difference between chromosomal sex and sexual differentiation?
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What does the term "homogametic sex" refer to?
What does the term "homogametic sex" refer to?
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Why are animal models used in research on DSDs?
Why are animal models used in research on DSDs?
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What does the Organizational/Activational Hypothesis primarily explain?
What does the Organizational/Activational Hypothesis primarily explain?
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When do organizational effects occur according to the Organizational/Activational Hypothesis?
When do organizational effects occur according to the Organizational/Activational Hypothesis?
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Which hormone is most significantly associated with organizational effects in early development?
Which hormone is most significantly associated with organizational effects in early development?
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How do activational effects differ from organizational effects?
How do activational effects differ from organizational effects?
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What was one significant result observed in 'hermaphrodite' female guinea pigs in Young's Experiment?
What was one significant result observed in 'hermaphrodite' female guinea pigs in Young's Experiment?
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What procedure was performed on all animals in Phase 2 of Young's Experiment?
What procedure was performed on all animals in Phase 2 of Young's Experiment?
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What is a primary characteristic of behavioral changes activated during adulthood?
What is a primary characteristic of behavioral changes activated during adulthood?
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What were the control groups established for in Young's Experiment?
What were the control groups established for in Young's Experiment?
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What does the organizational/activational hypothesis propose regarding prenatal hormones?
What does the organizational/activational hypothesis propose regarding prenatal hormones?
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What effect does testosterone have during the sensitive window of perinatal development?
What effect does testosterone have during the sensitive window of perinatal development?
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What behavior is exhibited by unmodified females exposed to early hormones?
What behavior is exhibited by unmodified females exposed to early hormones?
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Which of the following statements accurately describes the hormonal sex of an individual?
Which of the following statements accurately describes the hormonal sex of an individual?
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What was the purpose of removing gonads before day 10 in the hormone treatments?
What was the purpose of removing gonads before day 10 in the hormone treatments?
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What is required for females injected with testosterone before day 10 to show male-typical behavior in adulthood?
What is required for females injected with testosterone before day 10 to show male-typical behavior in adulthood?
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In mammals, which of the following statements about gametic sex is TRUE?
In mammals, which of the following statements about gametic sex is TRUE?
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What is a critical aspect of the hormonal effects during development according to the discussed experiment?
What is a critical aspect of the hormonal effects during development according to the discussed experiment?
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What is the primary function of the SRY gene in mammalian sex determination?
What is the primary function of the SRY gene in mammalian sex determination?
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What does lordosis behavior test for in hormone treatment experiments?
What does lordosis behavior test for in hormone treatment experiments?
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Which of the following is an example of how circulating testosterone levels can influence physical differences between males and females?
Which of the following is an example of how circulating testosterone levels can influence physical differences between males and females?
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Androgen Insensitivity Syndrome (AIS) is an example of how:
Androgen Insensitivity Syndrome (AIS) is an example of how:
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What was a key finding regarding control females in the experiment?
What was a key finding regarding control females in the experiment?
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Which of the following events is necessary for typical female development in mammals?
Which of the following events is necessary for typical female development in mammals?
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What is the role of estrogen in typical female development?
What is the role of estrogen in typical female development?
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Which of the following statements is TRUE about secondary sex characteristics in animals?
Which of the following statements is TRUE about secondary sex characteristics in animals?
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Which of the following syndromes involves an extra X chromosome in females?
Which of the following syndromes involves an extra X chromosome in females?
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What is the main evolutionary advantage of sexual reproduction?
What is the main evolutionary advantage of sexual reproduction?
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Which of the following is NOT a disadvantage of asexual reproduction?
Which of the following is NOT a disadvantage of asexual reproduction?
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What is the main characteristic of parthenogenesis?
What is the main characteristic of parthenogenesis?
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Which of the following animal groups is NOT known to reproduce asexually?
Which of the following animal groups is NOT known to reproduce asexually?
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Which of these syndromes is characterized by short stature, developmental delays, and infertility?
Which of these syndromes is characterized by short stature, developmental delays, and infertility?
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What is the primary reason for the evolutionary advantage of sexual reproduction over asexual reproduction?
What is the primary reason for the evolutionary advantage of sexual reproduction over asexual reproduction?
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Which of the following is a potential consequence of asexual reproduction?
Which of the following is a potential consequence of asexual reproduction?
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Which hormone is primarily responsible for increasing physical activity levels in boys during prenatal and postnatal development?
Which hormone is primarily responsible for increasing physical activity levels in boys during prenatal and postnatal development?
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What is the impact of prenatal stress on the development of sex-specific behaviors?
What is the impact of prenatal stress on the development of sex-specific behaviors?
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Which gene on the Y chromosome initiates the production of testosterone in males?
Which gene on the Y chromosome initiates the production of testosterone in males?
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How do epigenetic influences impact toy preferences in children?
How do epigenetic influences impact toy preferences in children?
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Which hormone is linked to enhanced verbal fluency and corpus callosum connectivity in females?
Which hormone is linked to enhanced verbal fluency and corpus callosum connectivity in females?
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Which of these is NOT mentioned as a factor influencing spatial abilities in either sex?
Which of these is NOT mentioned as a factor influencing spatial abilities in either sex?
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Which gene is associated with language development and is more active in females?
Which gene is associated with language development and is more active in females?
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How does early childhood experience modify FOXP2 expression?
How does early childhood experience modify FOXP2 expression?
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Which hormone is associated with increased competitiveness and impulsivity in males?
Which hormone is associated with increased competitiveness and impulsivity in males?
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The "warrior gene" (MAOA) plays a role in regulating which behavior?
The "warrior gene" (MAOA) plays a role in regulating which behavior?
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Which hormone is linked to enhanced emotional processing and social bonding in females?
Which hormone is linked to enhanced emotional processing and social bonding in females?
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Which gene is associated with oxytocin receptor methylation and influences social bonding?
Which gene is associated with oxytocin receptor methylation and influences social bonding?
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How does chronic stress affect the CRHR1 gene?
How does chronic stress affect the CRHR1 gene?
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Which of the following statements is TRUE about the influence of hormones on stress responses?
Which of the following statements is TRUE about the influence of hormones on stress responses?
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Which of the following MOST accurately describes the interaction between hormones and the development of sex-specific behaviors?
Which of the following MOST accurately describes the interaction between hormones and the development of sex-specific behaviors?
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Flashcards
XXYY Syndrome
XXYY Syndrome
A condition with two extra sex chromosomes in males, linked to tall stature and various developmental issues.
XXXX Syndrome
XXXX Syndrome
A genetic disorder in females characterized by two extra X chromosomes, resulting in developmental delays and short stature.
XXXXY Syndrome
XXXXY Syndrome
A severe disorder in males with three extra X chromosomes, leading to developmental and intellectual challenges.
XXXXX Syndrome
XXXXX Syndrome
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Asexual Reproduction
Asexual Reproduction
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Parthenogenesis
Parthenogenesis
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Sexual Reproduction
Sexual Reproduction
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Evolutionary Advantage
Evolutionary Advantage
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Heterogametic sex
Heterogametic sex
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Gonadal Sex
Gonadal Sex
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SRY gene
SRY gene
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Androgen Insensitivity Syndrome (AIS)
Androgen Insensitivity Syndrome (AIS)
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Sexual differentiation
Sexual differentiation
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Gametic Sex
Gametic Sex
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Hormonal Sex
Hormonal Sex
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Testosterone vs Estrogen Levels
Testosterone vs Estrogen Levels
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Proximate Cause
Proximate Cause
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Organizational/Activational Hypothesis
Organizational/Activational Hypothesis
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Organizational Effects
Organizational Effects
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Activational Effects
Activational Effects
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Disorders of Sex Development (DSD)
Disorders of Sex Development (DSD)
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Congenital Adrenal Hyperplasia (CAH)
Congenital Adrenal Hyperplasia (CAH)
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Chromosomal Sex
Chromosomal Sex
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Neural Circuits
Neural Circuits
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Testosterone's Role
Testosterone's Role
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Young's Experiment
Young's Experiment
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Hermaphrodite Females
Hermaphrodite Females
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Gonadectomy
Gonadectomy
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Organizational Hypothesis
Organizational Hypothesis
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Activational Hypothesis
Activational Hypothesis
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Critical periods for hormones
Critical periods for hormones
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Testosterone's role in behavior
Testosterone's role in behavior
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Effects of early testosterone on females
Effects of early testosterone on females
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Young’s Experiment
Young’s Experiment
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Removing gonads before day 10
Removing gonads before day 10
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Subtle neural changes
Subtle neural changes
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Hormones in Behavior
Hormones in Behavior
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Rough-and-Tumble Play
Rough-and-Tumble Play
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Toy Preferences
Toy Preferences
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Verbal Abilities
Verbal Abilities
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Spatial Abilities
Spatial Abilities
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Aggression & Risk-Taking
Aggression & Risk-Taking
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Empathy & Social Sensitivity
Empathy & Social Sensitivity
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Stress Response
Stress Response
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Estrogen's Influence
Estrogen's Influence
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Genetic Factors
Genetic Factors
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Epigenetic Influences
Epigenetic Influences
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Oxytocin's Role
Oxytocin's Role
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MAOA Gene
MAOA Gene
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Cortisol's Impact
Cortisol's Impact
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Study Notes
Sex Differences in Behavior
- Sex is a biological concept classifying organisms based on reproductive structures and functions.
- Sex is determined at multiple levels: chromosomal, gonadal, hormonal, morphological, and behavioral.
- Sex is often seen as binary (male/female), but variations exist.
- Examples of variations include Turner syndrome (XO) and Klinefelter syndrome (XXY), which challenge a strict binary model.
Understanding Sex and Gender
- Sex: Biological state with distinct facets (genetic, chromosomal, gonadal, hormonal, phenotypic).
- Gender: Subjective, self-identified social construct, influenced by biological, personal, and societal factors.
- Gender can vary widely (single, multiple, fluid).
- Intersex states (DSDs) occur when facets conflict.
Chromosomal Variations
- Turner Syndrome (45,X): Missing one X chromosome, leading to short stature, webbed neck, broad chest, and infertility.
- Klinefelter Syndrome (47,XXY): One extra X chromosome in males, characterized by tall stature, reduced muscle mass, breast development, and small testes.
- Triple X Syndrome (47,XXX): One extra X chromosome in females, with tall stature and sometimes mild developmental delays..
- XYY Syndrome (47,XYY): One extra Y chromosome in males, characterized by tall stature and sometimes developmental delays.
- XXYY Syndrome (48,XXYY): Two extra sex chromosomes (one X and one Y), resulting in tall stature, dental issues, and developmental delays.
- XXXX Syndrome (48,XXXX): Three extra X chromosomes in females.
- XXXXY Syndrome (49,XXXXY): Three extra X chromosomes and one Y chromosome, resulting in intellectual disability, speech and language delays.
- XXXXX Syndrome (49,XXXXX): Three extra X chromosomes in females. Significant intellectual disability, behavioral issues are more common.
Ultimate Causes of Sex Differences
- Ultimate cause: Evolutionary, adaptive reason for a behavior.
- Sexual dimorphism: Variations in appearance and behavior between sexes.
- Evolutionary analysis compares sexually monomorphic (similar-looking) species with sexually dimorphic (distinct traits) species.
- Monogamy: One mating partner, with decreased sexual dimorphism.
- Polygamy: Multiple partners, with stronger selection for exaggerated male traits.
- Example: Prairie voles (monogamous) vs. elk (polygynous).
Mating Systems and Sexual Selection
- Subcategory of natural selection.
- Male competition and female choice: Males develop traits (e.g., antlers in elk) to enhance reproductive success.
Proximate Causes of Sex Differences
- Proximate cause: Immediate, mechanistic cause of a behavior, focusing on how it occurs.
- Includes genetic, neural, hormonal, and environmental influences.
- Organizational effects: Early hormonal actions shaping neural circuits.
- Examples: Testosterone exposure influencing brain differentiation.
- Activational effects: Later hormonal actions triggering behaviors.
- Example: Testosterone promoting aggressive or reproductive behaviors.
Disorders of Sex Development (DSD)
- Congenital and acquired syndromes affecting sexual differentiation.
- May result from genetic mutations, endocrine disruptions, or environmental influences.
- Examples: Androgen Insensitivity Syndrome (AIS) and Congenital Adrenal Hyperplasia (CAH).
- Clinical and experimental studies provide insights into hormonal influences.
- Animal models are used to understand gender identity and sexual orientation.
Mammalian Sexual Differentiation
- Chromosomal sex: Defined by the sex chromosomes inherited at fertilization (XX for female, XY for male).
- Homogametic sex: Possesses two similar sex chromosomes.
- Heterogametic sex: Possesses two different sex chromosomes.
- Example: XX females in mammals, XY males in mammals.
- Gonadal sex: Determined by presence of ovaries or testes.
- SRY gene (on the Y chromosome) initiates testicular development.
- In absence of SRY, gonads develop into ovaries.
Gametic Sex
- Gametes: Produced by ovaries (ova) or testes (sperm).
- Ova are large, immobile, and resource-rich.
- Sperm are numerous, small, and mobile.
- Essential for sexual reproduction and genetic diversity.
- Example: Mammals produce fewer, high-investment ova in comparison to millions of daily sperm.
Differences in Circulating Testosterone and Estrogen Levels Between Men and Women
- Testosterone: Primarily produced in testes, higher levels in men. Physical and psychological differences include greater muscle mass, higher bone density, higher libido, and increased aggression.
- Estrogen: Primarily produced in ovaries, lower levels in men. Physical and psychological differences include lower muscle mass, contributes to sperm maturation, cardiovascular function and mood regulation.
Hormonal Differences and Their Effects on Men and Women
- Hormonal influence on libido differs between men and women:
- Hormones may impact cognitive function, spatial skills, social behaviors and emotional processing differently.
Morphological Sex
- Physical differences (e.g., size, external genitalia, secondary sexual characteristics) between males and females.
- Examples include coloration, horns, antlers.
- Behavioral sex: Sex-typical behaviors in different species (e.g., parental care, territorial defense, mating behaviors).
Effects of Hormones on Sexually Dimorphic Behaviors
- Hormonal influences lead to distinct behaviors exhibited by males and females.
- Animal models help understand neural, hormonal, and molecular mechanisms behind these behaviors.
- The role of hormones, notably gonadal steroids, in sex-specific behaviors: Hormones interact with genetics and environment to create behavior differences.
Experiment Summary
- Manipulation of hormones is important in understanding how hormones affect sexually dimorphic behaviors.
- Control groups are used to understand effect of removal or introduction of hormones.
- Males and females who have been raised with similar hormone levels to the other sex will generally display similar behaviours.
The Organizational/Activational Hypothesis
- Explanations of how hormones influence sexually dimorphic behaviors in mammals.
- Proposes a dual action of hormones during development:
- Organizational effects (early development): Establish permanent structural changes shaping the brain.
- Activational effects (later in life): Cause temporary influences on behavior by acting on pre-existing circuits.
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Description
Explore critical concepts related to hormones and their effects in this quiz. Understand the distinctions between organizational and activational effects, and delve into disorders of sexual development (DSDs) and their significance in research. Test your knowledge on chromosomal sex, sexual differentiation, and the use of animal models.