Homology-based Predictions and Ab Initio Methods Quiz

Known structure of homologous protein is required

Predicts structure based on principles of thermodynamics and physicochemical theory

X-ray crystallography

<p>Sensitivity measures what share of the actual positives are predicted</p> Signup and view all the answers

<p>Specificity measures what share of the predicted values are true</p> Signup and view all the answers

<p>Q3 Assessment measures the accuracy of individual amino acids</p> Signup and view all the answers

<p>Sov measures the percentage of correctly predicted secondary structures.</p> Signup and view all the answers

<p>Sov performs poorly when overlapping segments between predicted and observed structures are very fragmented.</p> Signup and view all the answers

<p>A high RMSD value indicates more discrepancies between observed and predicted structures.</p> Signup and view all the answers

<p>To avoid performance bias, the test dataset should not be homologous to the training set.</p> Signup and view all the answers

<p>Adding noise aims to prevent overfitting by introducing variation in predictions.</p> Signup and view all the answers

<p>Adding noise helps in avoiding overfitting in machine learning.</p> Signup and view all the answers