Podcast
Questions and Answers
Which type of pain is caused by injury to the nervous system?
Which type of pain is caused by injury to the nervous system?
- Chronic pain
- Acute pain
- Visceral pain
- Neuropathic pain (correct)
What is the defining time period for acute pain?
What is the defining time period for acute pain?
- 3-6 months
- More than 12 months
- 6-12 months
- Less than 3 months (correct)
What are the underlying mechanisms of acute pain?
What are the underlying mechanisms of acute pain?
- Direct activation of nerve receptors
- Receptors responding to tissue injury (correct)
- Peripheral sensitization
- Hyperalgesia
Which type of drugs inhibit prostaglandin synthesis and reduce peripheral sensitization?
Which type of drugs inhibit prostaglandin synthesis and reduce peripheral sensitization?
Which type of pain medication is not anti-inflammatory?
Which type of pain medication is not anti-inflammatory?
Which receptors can paracetamol activate in the central nervous system?
Which receptors can paracetamol activate in the central nervous system?
Which cream contains capsaicin?
Which cream contains capsaicin?
Where do opioids primarily work to relieve pain?
Where do opioids primarily work to relieve pain?
Which of the following is NOT a potential cause of neuropathic pain?
Which of the following is NOT a potential cause of neuropathic pain?
What percentage of the population is estimated to be affected by neuropathic pain?
What percentage of the population is estimated to be affected by neuropathic pain?
Which of the following words is NOT used by patients to describe neuropathic pain?
Which of the following words is NOT used by patients to describe neuropathic pain?
What are the two main peripheral mechanisms involved in neuropathic pain?
What are the two main peripheral mechanisms involved in neuropathic pain?
Which part of the nervous system do opioids work in to relieve pain?
Which part of the nervous system do opioids work in to relieve pain?
What is the mechanism called when blowing or rubbing an injury site reduces pain sensation?
What is the mechanism called when blowing or rubbing an injury site reduces pain sensation?
Which of the following is a chronic pain condition?
Which of the following is a chronic pain condition?
What is the difference between nociceptive pain and neuropathic pain?
What is the difference between nociceptive pain and neuropathic pain?
What is the difference between Hyperalgesia and Lavinia?
What is the difference between Hyperalgesia and Lavinia?
What is peripheral sensitization?
What is peripheral sensitization?
How is pain characterized in the last lecture?
How is pain characterized in the last lecture?
What is the focus of today's lecture?
What is the focus of today's lecture?
Which branch of the nervous system can close down the spinal summit pathway?
Which branch of the nervous system can close down the spinal summit pathway?
What happens when the activated collateral branches close down the spinal summit pathway?
What happens when the activated collateral branches close down the spinal summit pathway?
What is the role of the branches associated with second order neurones?
What is the role of the branches associated with second order neurones?
What happens when AP two fibres are activated?
What happens when AP two fibres are activated?
What is the result of a sensitized nervous system?
What is the result of a sensitized nervous system?
What do the collateral branches do when they are activated?
What do the collateral branches do when they are activated?
What is the mechanism responsible for spontaneous pain described by patients with phantom limb pain?
What is the mechanism responsible for spontaneous pain described by patients with phantom limb pain?
What is the basis of phantom limb pain?
What is the basis of phantom limb pain?
What is central sensitisation?
What is central sensitisation?
What are the consequences of prolonged depolarisation in second order neurons in the dorsal horn?
What are the consequences of prolonged depolarisation in second order neurons in the dorsal horn?
Which of the following is a characteristic of clinical pain?
Which of the following is a characteristic of clinical pain?
What is the defining time period for chronic pain according to the International Association for the Study of Pain?
What is the defining time period for chronic pain according to the International Association for the Study of Pain?
Which of the following is NOT a potential cause of acute pain?
Which of the following is NOT a potential cause of acute pain?
What is the primary site of action for acute pain treatments?
What is the primary site of action for acute pain treatments?
Which of the following substances can reduce the threshold of heat-activated channels (TRPV1) and contribute to hyperalgesia in acute pain?
Which of the following substances can reduce the threshold of heat-activated channels (TRPV1) and contribute to hyperalgesia in acute pain?
What is the mechanism responsible for the excitation of nociceptors in acute pain?
What is the mechanism responsible for the excitation of nociceptors in acute pain?
Which of the following is NOT a characteristic of neuropathic pain?
Which of the following is NOT a characteristic of neuropathic pain?
Where do opioids primarily work to relieve pain?
Where do opioids primarily work to relieve pain?
What is the result of peripheral sensitization in acute pain?
What is the result of peripheral sensitization in acute pain?
Which of the following is a characteristic of acute pain?
Which of the following is a characteristic of acute pain?
Which of the following drugs acts within the central nervous system and inhibits cyclooxygenase enzymes?
Which of the following drugs acts within the central nervous system and inhibits cyclooxygenase enzymes?
Which of the following drugs is a TRPV1 agonist and acts in the periphery by topically applying it to the skin?
Which of the following drugs is a TRPV1 agonist and acts in the periphery by topically applying it to the skin?
Which of the following drugs prevents nociceptor firing by blocking sodium channels?
Which of the following drugs prevents nociceptor firing by blocking sodium channels?
Which of the following drugs is NOT a non-steroidal anti-inflammatory drug (NSAID)?
Which of the following drugs is NOT a non-steroidal anti-inflammatory drug (NSAID)?
Which of the following drugs is an example of an opioid?
Which of the following drugs is an example of an opioid?
Which of the following mechanisms is responsible for reducing pain sensation by the simultaneous activation of low threshold mechanoreceptors?
Which of the following mechanisms is responsible for reducing pain sensation by the simultaneous activation of low threshold mechanoreceptors?
Which of the following is a common chronic pain condition?
Which of the following is a common chronic pain condition?
Which of the following is NOT a main peripheral mechanism involved in neuropathic pain?
Which of the following is NOT a main peripheral mechanism involved in neuropathic pain?
Which of the following is a potential cause of neuropathic pain?
Which of the following is a potential cause of neuropathic pain?
Which of the following is the mechanism responsible for spontaneous pain and phantom limb pain in the damaged tips of regenerating nerve endings?
Which of the following is the mechanism responsible for spontaneous pain and phantom limb pain in the damaged tips of regenerating nerve endings?
Which of the following is NOT a potential treatment for chronic pain?
Which of the following is NOT a potential treatment for chronic pain?
What is the mechanism of action of tricyclic antidepressants in the treatment of chronic pain?
What is the mechanism of action of tricyclic antidepressants in the treatment of chronic pain?
Which of the following is NOT a characteristic of central sensitization?
Which of the following is NOT a characteristic of central sensitization?
What is the first-line treatment recommended by NICE guidelines for neuropathic pain?
What is the first-line treatment recommended by NICE guidelines for neuropathic pain?
What is the proposed mechanism of action of anticonvulsants in the treatment of chronic pain?
What is the proposed mechanism of action of anticonvulsants in the treatment of chronic pain?
What is the primary focus of chronic pain treatments?
What is the primary focus of chronic pain treatments?
Which of the following is NOT a potential cause of central sensitization?
Which of the following is NOT a potential cause of central sensitization?
What is the primary mechanism of action of tricyclic antidepressants in the treatment of chronic pain?
What is the primary mechanism of action of tricyclic antidepressants in the treatment of chronic pain?
Which of the following is NOT a potential treatment for acute pain?
Which of the following is NOT a potential treatment for acute pain?
What is the second-line treatment recommended by NICE guidelines for neuropathic pain?
What is the second-line treatment recommended by NICE guidelines for neuropathic pain?
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