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Questions and Answers
What is the main difference between the polymorphism of class I and class II genes in humans?
What is the main difference between the polymorphism of class I and class II genes in humans?
- The polymorphism of class I genes is exclusively in the α chain, while that of class II genes is mainly in the β chains. (correct)
- The polymorphism of class I and class II genes is mainly in the α chains.
- The polymorphism of class I genes is mainly in the β chains, while that of class II genes is exclusively in the α chain.
- The polymorphism of class I and class II genes is mainly in the β chains.
What is an MHC haplotype?
What is an MHC haplotype?
- The total number of expressed class II molecules in an individual.
- The extra DRβ genes present in some individuals.
- The chance that two siblings will inherit identical sets of HLA alleles.
- The set of MHC genes present on each chromosome, which are inherited together in a Mendelian fashion. (correct)
Why are siblings often tested before unrelated individuals for their suitability as donors for transplantation?
Why are siblings often tested before unrelated individuals for their suitability as donors for transplantation?
- Because siblings have a higher probability of developing immune rejection after transplantation.
- Because siblings have a higher probability of carrying infectious diseases that can be transmitted to the recipient.
- Because siblings are more likely to have a higher level of HLA antibodies than unrelated individuals.
- Because the chance of finding an HLA match with the recipient is much greater for siblings, as they have a 25% chance of inheriting identical sets of HLA alleles. (correct)
