22 Questions
Which of the following is true about the CD system used in immunophenotyping?
CD system is used to define cells based on their surface molecules
What is the function of the thymus?
Education of T-cells
What is the percentage of cellularity in the bone marrow at 10 years old?
90% cellular
Which type of T cells are the major regulators of the immune response and produce lymphokines?
Helper T cells
Which type of T cells mediate the killing of cells, viruses, tumors, and transplants?
Cytotoxic T cells
Which type of cells are responsible for direct killing of viruses, tumors, and transplants?
Natural Killer cells
Which type of cells produce cytokines and lymphokines to ensure a robust immune response?
All of the above
Which of the following is NOT a type of antigen?
Immunoglobulins
Which of the following is the correct order of immunoglobulin abundance in plasma?
IgG > IgA > IgM > IgD > IgE
Which region of an antibody is responsible for binding to antigens?
Fab region
What is the purpose of adjuvants in vaccines?
To help or enhance vaccine efficacy
Which of the following is true about Staphylococcus epidermidis?
Most strains do not cause illness.
What type of infections does Staphylococcus epidermidis commonly cause?
Skin infections
What is the term used to describe Staphylococcus epidermidis strains that are resistant to multiple antibiotics?
MRSA strains
Which of the following is NOT a function of the thymus?
Production of B lymphocytes
Which of the following is a characteristic of lymph nodes?
They have a cortex with a lot of T lymphocytes
What is the primary function of dendritic cells?
Antigen presentation
Which type of immunity is characterized by the production of antibodies?
Humoral immunity
Which chromosome is the Human Major Histocompatibility Complex Class II D region located on?
Chromosome #6
What are the three major classes coded by the Human Major Histocompatibility Complex?
Class I- A, B, C; Class II- DP, DQ, DR; Class III
Which cells are responsible for processing and presenting antigens to T cells?
Dendritic cells, B cells or macrophages
What is the role of Antigen Presenting Cells (APCs) in T cell responses?
APCs are key to the genesis of T cell responses
Test your knowledge of the human major histocompatibility complex (MHC) and its role in immune responses. Learn about MHC class I, II, and III molecules, minor antigens, and the genetic differences in the MHC class II D region. Explore how MHC molecules, also known as Human Leukocyte Antigens (HLA), are used in transplant matching.
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