HIV Biology and Structure
18 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the function of reverse transcriptase in the HIV virus?

  • It makes DNA from RNA (correct)
  • It forms the conical capsid
  • It cleaves proteins
  • It integrates DNA into the host cell DNA

Which type of HIV virus replicates in monocytes and macrophages?

  • CCR5-tropic viruses (correct)
  • Dendritic cell-tropic viruses
  • T-cell-tropic viruses
  • CXCR4-tropic viruses

What is the major lymphocyte receptor used by HIV to enter cells?

  • CXCR4
  • CD4 (correct)
  • p24
  • CCR5

What is the role of the V3 loop in the gp120 protein of HIV?

<p>It mutates rapidly (D)</p> Signup and view all the answers

Which protein on the envelope of HIV is responsible for attachment to T-cells?

<p>gp120 (C)</p> Signup and view all the answers

Which enzyme is responsible for integrating viral DNA into the host cell DNA?

<p>Integrase (B)</p> Signup and view all the answers

What is the natural host of the HIV virus?

<p>Humans (D)</p> Signup and view all the answers

Which protein is responsible for fusion and entry of HIV into T-cells?

<p>gp41 (D)</p> Signup and view all the answers

Which type of blood transfusion reaction is characterized by a Type I hypersensitivity reaction against plasma proteins in transfused blood?

<p>Allergic/anaphylactic reaction (C)</p> Signup and view all the answers

What precaution should be taken for IgA-deficient individuals when receiving blood products?

<p>Receive blood products without IgA (B)</p> Signup and view all the answers

Which type of blood transfusion reaction is characterized by intravascular hemolysis due to ABO blood group incompatibility?

<p>Type II hypersensitivity reaction (D)</p> Signup and view all the answers

What is the main cause of febrile nonhemolytic transfusion reactions during the storage of blood transfusion products?

<p>Accumulation of cytokines created by WBCs (D)</p> Signup and view all the answers

Which of the following clinical presentations is most commonly seen in children with the described condition?

<p>Fever, headaches, chills, flushing (C)</p> Signup and view all the answers

Which of the following best describes the two-hit mechanism involved in the pathophysiology of the described condition?

<p>Neutrophils are sequestered and primed in pulmonary vasculature due to recipient risk factors, then activated by a product in the transfused blood and release inflammatory mediators (D)</p> Signup and view all the answers

Which of the following blood components is involved in the anamnestic response in the described condition?

<p>Donor RBC with A and/ or B group antigens (B)</p> Signup and view all the answers

Which of the following immunoglobulins is involved in the host immune response against donor RBC with foreign antigens?

<p>IgG (A)</p> Signup and view all the answers

Which type of blood cells release preformed cytokines that contribute to the pathophysiology of the described condition?

<p>Neutrophils (A)</p> Signup and view all the answers

What is the characteristic onset timeframe for the clinical presentation of the described condition due to slow destruction by reticuloendothelial system?

<p>Within 1-2 weeks (D)</p> Signup and view all the answers

More Like This

HIV Retrovirus and AIDS Quiz
10 questions
retrovirus
20 questions

retrovirus

PrivilegedCoralReef avatar
PrivilegedCoralReef
HIV Infection and Immunology
7 questions

HIV Infection and Immunology

HeavenlyLapisLazuli avatar
HeavenlyLapisLazuli
HIV Structure and Replication
16 questions

HIV Structure and Replication

RationalExpressionism avatar
RationalExpressionism
Use Quizgecko on...
Browser
Browser