HIV Retrovirus and AIDS Quiz
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Questions and Answers

What is the main target of HIV infection?

  • Epithelial cells and fibroblasts
  • Red blood cells and platelets
  • CD4+ T cells, macrophages, and dendritic cells (correct)
  • B cells and natural killer cells
  • Which statement about HIV-1 is true?

  • It is less virulent than HIV-2
  • It is highly susceptible to mutations (correct)
  • It causes infections only in specific regions
  • It is a less common cause of AIDS
  • What are the components of HIV virion?

  • Glycoprotein envelope, matrix layer, capsid (correct)
  • Lipid bilayer, ribosomes, cytoplasm
  • Nucleus, mitochondria, endoplasmic reticulum
  • RNA core, DNA envelope, protein layer
  • Which statement about HIV-2 is true?

    <p>It causes infection in specific regions e.g. West Africa, Mozambique</p> Signup and view all the answers

    What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?

    <p>Acquired ImmunoDeficiency Syndrome (AIDS)</p> Signup and view all the answers

    Which cells does HIV mainly infect?

    <p>CD4+ T cells, macrophages, and dendritic cells</p> Signup and view all the answers

    Which virus causes the infection in specific regions like West Africa and Mozambique?

    <p>HIV-2</p> Signup and view all the answers

    Which genus of retrovirus includes the subspecies HIV-1 and HIV-2?

    <p>Lentivirus</p> Signup and view all the answers

    What are the characteristics of HIV virion?

    <p>Icosahedral (20-sided), enveloped virus with glycoprotein envelope, matrix layer, and capsid</p> Signup and view all the answers

    What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?

    <p>Acquired ImmunoDeficiency Syndrome (AIDS)</p> Signup and view all the answers

    Study Notes

    HIV Infection

    • The main target of HIV infection is CD4+ T cells.

    HIV-1

    • HIV-1 is the most virulent and prevalent form of HIV.

    HIV Virion Components

    • The components of HIV virion are two copies of single-stranded RNA, Reverse Transcriptase, Integrase, Protease, and structural proteins.

    HIV-2

    • HIV-2 is less virulent and less prevalent than HIV-1, but still causes AIDS.

    AIDS

    • The end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections is AIDS (Acquired Immune Deficiency Syndrome).

    Cells Infected by HIV

    • HIV mainly infects CD4+ T cells, macrophages, and dendritic cells.

    HIV-2 Prevalence

    • HIV-2 is the cause of infection in specific regions like West Africa and Mozambique.

    Retrovirus Genus

    • The genus of retrovirus that includes the subspecies HIV-1 and HIV-2 is Lentivirus.

    HIV Virion Characteristics

    • HIV virion has a lipid bilayer envelope, is spherical in shape, and is approximately 100-120 nm in diameter.

    AIDS (Again)

    • The end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections is AIDS (Acquired Immune Deficiency Syndrome).

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    Description

    Test your knowledge of HIV, a retrovirus that causes AIDS. Learn about the infection process, target cells, and the impact on the immune system.

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