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Questions and Answers
What is the main target of HIV infection?
What is the main target of HIV infection?
- Epithelial cells and fibroblasts
- Red blood cells and platelets
- CD4+ T cells, macrophages, and dendritic cells (correct)
- B cells and natural killer cells
Which statement about HIV-1 is true?
Which statement about HIV-1 is true?
- It is less virulent than HIV-2
- It is highly susceptible to mutations (correct)
- It causes infections only in specific regions
- It is a less common cause of AIDS
What are the components of HIV virion?
What are the components of HIV virion?
- Glycoprotein envelope, matrix layer, capsid (correct)
- Lipid bilayer, ribosomes, cytoplasm
- Nucleus, mitochondria, endoplasmic reticulum
- RNA core, DNA envelope, protein layer
Which statement about HIV-2 is true?
Which statement about HIV-2 is true?
What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?
What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?
Which cells does HIV mainly infect?
Which cells does HIV mainly infect?
Which virus causes the infection in specific regions like West Africa and Mozambique?
Which virus causes the infection in specific regions like West Africa and Mozambique?
Which genus of retrovirus includes the subspecies HIV-1 and HIV-2?
Which genus of retrovirus includes the subspecies HIV-1 and HIV-2?
What are the characteristics of HIV virion?
What are the characteristics of HIV virion?
What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?
What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?
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Study Notes
HIV Infection
- The main target of HIV infection is CD4+ T cells.
HIV-1
- HIV-1 is the most virulent and prevalent form of HIV.
HIV Virion Components
- The components of HIV virion are two copies of single-stranded RNA, Reverse Transcriptase, Integrase, Protease, and structural proteins.
HIV-2
- HIV-2 is less virulent and less prevalent than HIV-1, but still causes AIDS.
AIDS
- The end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections is AIDS (Acquired Immune Deficiency Syndrome).
Cells Infected by HIV
- HIV mainly infects CD4+ T cells, macrophages, and dendritic cells.
HIV-2 Prevalence
- HIV-2 is the cause of infection in specific regions like West Africa and Mozambique.
Retrovirus Genus
- The genus of retrovirus that includes the subspecies HIV-1 and HIV-2 is Lentivirus.
HIV Virion Characteristics
- HIV virion has a lipid bilayer envelope, is spherical in shape, and is approximately 100-120 nm in diameter.
AIDS (Again)
- The end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections is AIDS (Acquired Immune Deficiency Syndrome).
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