HIV Retrovirus and AIDS Quiz

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Questions and Answers

What is the main target of HIV infection?

  • Epithelial cells and fibroblasts
  • Red blood cells and platelets
  • CD4+ T cells, macrophages, and dendritic cells (correct)
  • B cells and natural killer cells

Which statement about HIV-1 is true?

  • It is less virulent than HIV-2
  • It is highly susceptible to mutations (correct)
  • It causes infections only in specific regions
  • It is a less common cause of AIDS

What are the components of HIV virion?

  • Glycoprotein envelope, matrix layer, capsid (correct)
  • Lipid bilayer, ribosomes, cytoplasm
  • Nucleus, mitochondria, endoplasmic reticulum
  • RNA core, DNA envelope, protein layer

Which statement about HIV-2 is true?

<p>It causes infection in specific regions e.g. West Africa, Mozambique (D)</p> Signup and view all the answers

What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?

<p>Acquired ImmunoDeficiency Syndrome (AIDS) (C)</p> Signup and view all the answers

Which cells does HIV mainly infect?

<p>CD4+ T cells, macrophages, and dendritic cells (B)</p> Signup and view all the answers

Which virus causes the infection in specific regions like West Africa and Mozambique?

<p>HIV-2 (A)</p> Signup and view all the answers

Which genus of retrovirus includes the subspecies HIV-1 and HIV-2?

<p>Lentivirus (D)</p> Signup and view all the answers

What are the characteristics of HIV virion?

<p>Icosahedral (20-sided), enveloped virus with glycoprotein envelope, matrix layer, and capsid (B)</p> Signup and view all the answers

What is the end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections?

<p>Acquired ImmunoDeficiency Syndrome (AIDS) (A)</p> Signup and view all the answers

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Study Notes

HIV Infection

  • The main target of HIV infection is CD4+ T cells.

HIV-1

  • HIV-1 is the most virulent and prevalent form of HIV.

HIV Virion Components

  • The components of HIV virion are two copies of single-stranded RNA, Reverse Transcriptase, Integrase, Protease, and structural proteins.

HIV-2

  • HIV-2 is less virulent and less prevalent than HIV-1, but still causes AIDS.

AIDS

  • The end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections is AIDS (Acquired Immune Deficiency Syndrome).

Cells Infected by HIV

  • HIV mainly infects CD4+ T cells, macrophages, and dendritic cells.

HIV-2 Prevalence

  • HIV-2 is the cause of infection in specific regions like West Africa and Mozambique.

Retrovirus Genus

  • The genus of retrovirus that includes the subspecies HIV-1 and HIV-2 is Lentivirus.

HIV Virion Characteristics

  • HIV virion has a lipid bilayer envelope, is spherical in shape, and is approximately 100-120 nm in diameter.

AIDS (Again)

  • The end stage of the disease associated with CD4+ T cell depletion and multiple opportunistic infections is AIDS (Acquired Immune Deficiency Syndrome).

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