Virus Structure: HIV and Retrovirus Basics
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Questions and Answers

Which proteins in HIV make the spikes?

  • gp121 and gp41
  • gp121 and gp41
  • gp120 and gp41 (correct)
  • gp120 and gp40
  • What proteins in HIV form the Matrix and contribute to the core?

  • P24 and p14
  • P24 and p17
  • P17 and pp27
  • P17 and p24 (correct)
  • Under which subclass does HIV fall within the Retrovirus class?

  • Superclass Psu virus
  • None of these
  • Subclass lentivirus (correct)
  • Superclass lentivirus
  • The genes gag, pol, and env in HIV are responsible for synthesizing which type of particles?

    <p>HIV particle</p> Signup and view all the answers

    The HIV genes tat, rev, nef, vif, vpr, and vpu are involved in controlling which process?

    <p>Infection</p> Signup and view all the answers

    Study Notes

    HIV Proteins and Structure

    • Spikes Composition: HIV spikes are comprised of gp120 and gp41 proteins, crucial for virus attachment and entry into host cells.
    • Core Formation: The matrix and core of HIV are formed by proteins P17 and P24, essential for structural integrity and protection of viral RNA.
    • Virus Classification: HIV is classified as a retrovirus, specifically within the subclass lentivirus, indicating its capacity to integrate into the host genome.

    Gene Functionality

    • Key Genes: The three main HIV genes—gag, pol, and env—are responsible for synthesizing new HIV particles, enabling replication and expression of the virus.
    • Regulatory Genes: Additional genes tat, rev, nef, vif, vpr, and vpu play a vital role in controlling infection and regulating viral life cycle processes, including gene expression and immune evasion.

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    Description

    Test your knowledge on the structure of HIV and its classification as a retrovirus. This quiz covers key protein components and their roles within the virus. Perfect for students studying virology and microbiology.

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