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Questions and Answers
Which proteins in HIV make the spikes?
Which proteins in HIV make the spikes?
- gp121 and gp41
- gp121 and gp41
- gp120 and gp41 (correct)
- gp120 and gp40
What proteins in HIV form the Matrix and contribute to the core?
What proteins in HIV form the Matrix and contribute to the core?
- P24 and p14
- P24 and p17
- P17 and pp27
- P17 and p24 (correct)
Under which subclass does HIV fall within the Retrovirus class?
Under which subclass does HIV fall within the Retrovirus class?
- Superclass Psu virus
- None of these
- Subclass lentivirus (correct)
- Superclass lentivirus
The genes gag, pol, and env in HIV are responsible for synthesizing which type of particles?
The genes gag, pol, and env in HIV are responsible for synthesizing which type of particles?
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The HIV genes tat, rev, nef, vif, vpr, and vpu are involved in controlling which process?
The HIV genes tat, rev, nef, vif, vpr, and vpu are involved in controlling which process?
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Study Notes
HIV Proteins and Structure
- Spikes Composition: HIV spikes are comprised of gp120 and gp41 proteins, crucial for virus attachment and entry into host cells.
- Core Formation: The matrix and core of HIV are formed by proteins P17 and P24, essential for structural integrity and protection of viral RNA.
- Virus Classification: HIV is classified as a retrovirus, specifically within the subclass lentivirus, indicating its capacity to integrate into the host genome.
Gene Functionality
- Key Genes: The three main HIV genes—gag, pol, and env—are responsible for synthesizing new HIV particles, enabling replication and expression of the virus.
- Regulatory Genes: Additional genes tat, rev, nef, vif, vpr, and vpu play a vital role in controlling infection and regulating viral life cycle processes, including gene expression and immune evasion.
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