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Questions and Answers
What is the role of ALIX in HIV-1 subtype C p6-Gag?
What is the role of ALIX in HIV-1 subtype C p6-Gag?
- It links HIV-1 Gag to the components of ESCRT-III (correct)
- It inhibits the release defect of PTAP deleted HIV-1
- It enhances the nucleocapsid of HIV-1 subtype C
- It is responsible for PTAP deletion in HIV-1 subtype C
What is the function of PYRE insertion in HIV-1 subtype C p6?
What is the function of PYRE insertion in HIV-1 subtype C p6?
- To inhibit the release defect of PTAP deleted HIV-1
- To facilitate PTAP deletion in HIV-1 subtype C
- To restore the ALIX binding site (correct)
- To enhance the nucleocapsid of HIV-1 subtype C
What does the study show about the response of HIV-1 construct with subtype C p6 having PTAP deletion and PYRE insertion to ALIX overexpression?
What does the study show about the response of HIV-1 construct with subtype C p6 having PTAP deletion and PYRE insertion to ALIX overexpression?
- It showed increased release defect
- It failed to respond to ALIX overexpression
- It could respond to ALIX overexpression (correct)
- It resulted in PTAP restoration
What is the impact of the lack of LYPXnL motif in HIV-1 subtype C?
What is the impact of the lack of LYPXnL motif in HIV-1 subtype C?
What is critical for the response of HIV-1 construct with subtype C p6 having PTAP deletion and PYRE insertion to ALIX overexpression?
What is critical for the response of HIV-1 construct with subtype C p6 having PTAP deletion and PYRE insertion to ALIX overexpression?
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