Podcast
Questions and Answers
What is the primary function of the temporal lobe?
What is the primary function of the temporal lobe?
What is the prefrontal cortex responsible for?
What is the prefrontal cortex responsible for?
Which part of the brain is responsible for synthesizing all information received from other parts of the brain and decides how to respond?
Which part of the brain is responsible for synthesizing all information received from other parts of the brain and decides how to respond?
What is the primary function of the autonomic nervous system?
What is the primary function of the autonomic nervous system?
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Which part of the brain is associated with perceiving the world around us and creating images?
Which part of the brain is associated with perceiving the world around us and creating images?
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What is the function of the parietal lobe?
What is the function of the parietal lobe?
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What is the function of the somatic nervous system?
What is the function of the somatic nervous system?
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What is the function of the occipital lobe?
What is the function of the occipital lobe?
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What is the phenomenon known as when behavior changes as a result of a person's expectation of change?
What is the phenomenon known as when behavior changes as a result of a person's expectation of change?
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What is the purpose of comparative treatment research?
What is the purpose of comparative treatment research?
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What is the main strategy used in single-case experimental design?
What is the main strategy used in single-case experimental design?
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What are endophenotypes in the context of psychological disorders?
What are endophenotypes in the context of psychological disorders?
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What is the goal of researchers studying schizophrenia in the context of endophenotypes?
What is the goal of researchers studying schizophrenia in the context of endophenotypes?
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What is the principle of genetic linkage analysis?
What is the principle of genetic linkage analysis?
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What is the purpose of using genetic markers in genetic linkage analysis?
What is the purpose of using genetic markers in genetic linkage analysis?
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What is the outcome when a match is found between the inheritance of a disorder and a genetic marker?
What is the outcome when a match is found between the inheritance of a disorder and a genetic marker?
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What is a characteristic behavior of a child with disinhibited social engagement disorder?
What is a characteristic behavior of a child with disinhibited social engagement disorder?
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In Obsessive-Compulsive Disorder (OCD), what is the source of the danger?
In Obsessive-Compulsive Disorder (OCD), what is the source of the danger?
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What is the purpose of compulsions in Obsessive-Compulsive Disorder (OCD)?
What is the purpose of compulsions in Obsessive-Compulsive Disorder (OCD)?
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What is the most common type of obsession in Obsessive-Compulsive Disorder (OCD)?
What is the most common type of obsession in Obsessive-Compulsive Disorder (OCD)?
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What is a characteristic of symmetry obsessions in Obsessive-Compulsive Disorder (OCD)?
What is a characteristic of symmetry obsessions in Obsessive-Compulsive Disorder (OCD)?
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What is a common behavior of individuals with forbidden thoughts or actions obsessions in Obsessive-Compulsive Disorder (OCD)?
What is a common behavior of individuals with forbidden thoughts or actions obsessions in Obsessive-Compulsive Disorder (OCD)?
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What is the approximate percentage of symmetry obsessions in Obsessive-Compulsive Disorder (OCD)?
What is the approximate percentage of symmetry obsessions in Obsessive-Compulsive Disorder (OCD)?
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What is the purpose of checking rituals in Obsessive-Compulsive Disorder (OCD)?
What is the purpose of checking rituals in Obsessive-Compulsive Disorder (OCD)?
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In what century did asylums first appear?
In what century did asylums first appear?
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What was the main factor that contributed to the decline of moral therapy in asylums?
What was the main factor that contributed to the decline of moral therapy in asylums?
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Who is credited with introducing moral therapy in the United States?
Who is credited with introducing moral therapy in the United States?
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What was the primary goal of Dorothea Dix's mental hygiene movement?
What was the primary goal of Dorothea Dix's mental hygiene movement?
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What did Franz Mesmer attribute the problem of his patients to?
What did Franz Mesmer attribute the problem of his patients to?
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Who is widely regarded as the father of hypnosis?
Who is widely regarded as the father of hypnosis?
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What was the ideal institution size for moral therapy to be effective?
What was the ideal institution size for moral therapy to be effective?
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Who was interested in Franz Mesmer's methods of suggestion?
Who was interested in Franz Mesmer's methods of suggestion?
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What percentage of individuals with GAD are female in clinical samples?
What percentage of individuals with GAD are female in clinical samples?
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What is the median age of onset of GAD based on interviews?
What is the median age of onset of GAD based on interviews?
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Which group has the highest prevalence of GAD according to the national comorbidity study?
Which group has the highest prevalence of GAD according to the national comorbidity study?
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What is a potential risk of benzodiazepines in older adults?
What is a potential risk of benzodiazepines in older adults?
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Which medication is associated with a stronger evidence base for the treatment of GAD?
Which medication is associated with a stronger evidence base for the treatment of GAD?
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What is the focus of cognitive-behavioral therapy (CBT) for GAD?
What is the focus of cognitive-behavioral therapy (CBT) for GAD?
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Which of the following is a potential consequence of taking benzodiazepines?
Which of the following is a potential consequence of taking benzodiazepines?
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What is the result of a comparison between CBT and the antidepressant drug sertraline (Zoloft) for children with GAD?
What is the result of a comparison between CBT and the antidepressant drug sertraline (Zoloft) for children with GAD?
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What is the minimum time that must pass after a trauma for a PTSD diagnosis to be made?
What is the minimum time that must pass after a trauma for a PTSD diagnosis to be made?
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What percentage of the population has experienced PTSD at some point in their life?
What percentage of the population has experienced PTSD at some point in their life?
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What is the primary focus of counseling psychologists?
What is the primary focus of counseling psychologists?
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What degree do psychiatrists typically earn?
What degree do psychiatrists typically earn?
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What is the key factor that contributes to the development of PTSD?
What is the key factor that contributes to the development of PTSD?
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What is a predictor of suicidal attempts, independent of other problems?
What is a predictor of suicidal attempts, independent of other problems?
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What type of training do Ph.D. programs in universities emphasize?
What type of training do Ph.D. programs in universities emphasize?
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What type of professionals work with patients with psychological disorders, often in hospitals as part of a treatment team?
What type of professionals work with patients with psychological disorders, often in hospitals as part of a treatment team?
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What contributes to the etiology of PTSD, but does not account for all of it?
What contributes to the etiology of PTSD, but does not account for all of it?
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What is the term for the number of people in the population as a whole who have a particular disorder?
What is the term for the number of people in the population as a whole who have a particular disorder?
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What is associated with a generalized biological vulnerability for PTSD?
What is associated with a generalized biological vulnerability for PTSD?
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What type of approach do many mental health professionals take in their clinical work?
What type of approach do many mental health professionals take in their clinical work?
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What specific characteristic of the serotonin transporter gene increases the probability of becoming depressed?
What specific characteristic of the serotonin transporter gene increases the probability of becoming depressed?
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What is the name of the disorder that is essentially PTSD, but occurs within the first month after a trauma?
What is the name of the disorder that is essentially PTSD, but occurs within the first month after a trauma?
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What type of degree do psychiatric social workers typically earn?
What type of degree do psychiatric social workers typically earn?
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What type of professionals provide clinical services, usually under the supervision of a doctoral-level clinician?
What type of professionals provide clinical services, usually under the supervision of a doctoral-level clinician?
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What is the prevalence of Social Anxiety Disorder (SAD) in a given 1-year period?
What is the prevalence of Social Anxiety Disorder (SAD) in a given 1-year period?
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What is the sex ratio for Social Anxiety Disorder (SAD)?
What is the sex ratio for Social Anxiety Disorder (SAD)?
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At what age do people with SAD usually begin to exhibit symptoms?
At what age do people with SAD usually begin to exhibit symptoms?
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What is a characteristic of people who are more likely to have SAD?
What is a characteristic of people who are more likely to have SAD?
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What did Mogg and colleagues find about socially anxious individuals?
What did Mogg and colleagues find about socially anxious individuals?
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Why might humans have inherited a tendency to fear angry faces?
Why might humans have inherited a tendency to fear angry faces?
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What is a characteristic of some infants born with a temperamental trait of inhibition or shyness?
What is a characteristic of some infants born with a temperamental trait of inhibition or shyness?
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What is the primary focus of Clark and colleagues' cognitive therapy program?
What is the primary focus of Clark and colleagues' cognitive therapy program?
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What is the effect of L-dopa on dopamine levels?
What is the effect of L-dopa on dopamine levels?
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What is the primary characteristic of learned helplessness?
What is the primary characteristic of learned helplessness?
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What is the primary function of dopamine in the locomotor system?
What is the primary function of dopamine in the locomotor system?
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What is the concept of prepared learning related to?
What is the concept of prepared learning related to?
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What is the effect of serotonin on the locomotor system?
What is the effect of serotonin on the locomotor system?
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What is the primary characteristic of observational learning?
What is the primary characteristic of observational learning?
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What is the association between dopamine and behavior?
What is the association between dopamine and behavior?
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What is the result of deficiencies in dopamine in the brain?
What is the result of deficiencies in dopamine in the brain?
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What is the primary symptom of panic disorder?
What is the primary symptom of panic disorder?
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What is the relationship between panic disorder and agoraphobia?
What is the relationship between panic disorder and agoraphobia?
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What is required to meet the criteria for panic disorder?
What is required to meet the criteria for panic disorder?
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What is the term 'agoraphobia' originally derived from?
What is the term 'agoraphobia' originally derived from?
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Why do individuals with agoraphobia often avoid certain situations?
Why do individuals with agoraphobia often avoid certain situations?
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What is the primary role of 'safe' locations or people in agoraphobia?
What is the primary role of 'safe' locations or people in agoraphobia?
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What is the relationship between panic disorder and agoraphobic avoidance behavior?
What is the relationship between panic disorder and agoraphobic avoidance behavior?
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What is a characteristic of some individuals with panic disorder who do not report concern about another attack?
What is a characteristic of some individuals with panic disorder who do not report concern about another attack?
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What is the role of GABA in the brain?
What is the role of GABA in the brain?
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What is the function of agonists in researching neurotransmitters?
What is the function of agonists in researching neurotransmitters?
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What is the result of blocking the reuptake process of neurotransmitters?
What is the result of blocking the reuptake process of neurotransmitters?
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What is the effect of benzodiazepines on GABA?
What is the effect of benzodiazepines on GABA?
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What is the role of glutamate in the brain?
What is the role of glutamate in the brain?
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What is the term for the process of drawing neurotransmitters back into the neuron after release?
What is the term for the process of drawing neurotransmitters back into the neuron after release?
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What is the system that produces the stress hormone cortisol?
What is the system that produces the stress hormone cortisol?
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What is the distribution of the GABA system in the brain?
What is the distribution of the GABA system in the brain?
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What is the function of dopamine agonist L-dopa in the context of Parkinson's disease?
What is the function of dopamine agonist L-dopa in the context of Parkinson's disease?
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What is the phenomenon described by Martin Seligman and Steven Maier?
What is the phenomenon described by Martin Seligman and Steven Maier?
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What is the primary function of dopamine in the context of behavior?
What is the primary function of dopamine in the context of behavior?
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What is the concept that describes how we learn about certain types of objects or situations over the course of evolution?
What is the concept that describes how we learn about certain types of objects or situations over the course of evolution?
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What is the function of serotonin in the context of locomotor activity?
What is the function of serotonin in the context of locomotor activity?
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What is the focus of the field of cognitive science?
What is the focus of the field of cognitive science?
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What is the result of deficiencies in dopamine?
What is the result of deficiencies in dopamine?
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What is the concept described by Albert Bandura?
What is the concept described by Albert Bandura?
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What is the primary limitation of cross-sectional design?
What is the primary limitation of cross-sectional design?
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What is the main advantage of longitudinal designs?
What is the main advantage of longitudinal designs?
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What is the primary difference between anxiety and fear?
What is the primary difference between anxiety and fear?
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What is the primary characteristic of a panic attack?
What is the primary characteristic of a panic attack?
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What is the primary difference between expected and unexpected panic attacks?
What is the primary difference between expected and unexpected panic attacks?
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What is the cross-generational effect?
What is the cross-generational effect?
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What is a limitation of longitudinal designs?
What is a limitation of longitudinal designs?
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What is the primary focus of researchers using longitudinal designs?
What is the primary focus of researchers using longitudinal designs?
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Which system is responsible for relaying potential danger signals from the brain stem to higher cortical processes?
Which system is responsible for relaying potential danger signals from the brain stem to higher cortical processes?
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What is the primary function of the behavioral inhibition system (BIS)?
What is the primary function of the behavioral inhibition system (BIS)?
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What is the difference between the behavioral inhibition system (BIS) and the fight/flight system (FFS)?
What is the difference between the behavioral inhibition system (BIS) and the fight/flight system (FFS)?
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What is the result of cigarette smoking as a teenager, according to one study?
What is the result of cigarette smoking as a teenager, according to one study?
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What structure receives a big boost from the amygdala when the BIS is activated?
What structure receives a big boost from the amygdala when the BIS is activated?
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What is the primary role of the brain stem in relation to anxiety?
What is the primary role of the brain stem in relation to anxiety?
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Which system is involved in the immediate alarm-and-escape response?
Which system is involved in the immediate alarm-and-escape response?
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What is the potential consequence of deficiencies in serotonin, according to Gray and McNaughton?
What is the potential consequence of deficiencies in serotonin, according to Gray and McNaughton?
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What is a characteristic of high-potency benzodiazepines such as alprazolam (Xanax)?
What is a characteristic of high-potency benzodiazepines such as alprazolam (Xanax)?
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What is the goal of exposure-based treatments for panic disorder?
What is the goal of exposure-based treatments for panic disorder?
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What is the focus of panic control treatment (PCT) developed at one of the clinics?
What is the focus of panic control treatment (PCT) developed at one of the clinics?
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What is the recommended treatment approach for patients with panic disorder and agoraphobia?
What is the recommended treatment approach for patients with panic disorder and agoraphobia?
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What is a characteristic of specific phobia?
What is a characteristic of specific phobia?
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What is the outcome of comparing the effectiveness of CBT and drug treatment for panic disorder and agoraphobia?
What is the outcome of comparing the effectiveness of CBT and drug treatment for panic disorder and agoraphobia?
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What is the purpose of gradual exposure exercises in the treatment of agoraphobic behavior?
What is the purpose of gradual exposure exercises in the treatment of agoraphobic behavior?
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What is the effect of combining drugs and CBT initially for panic disorder and agoraphobia?
What is the effect of combining drugs and CBT initially for panic disorder and agoraphobia?
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What is the function of the midbrain in the brain stem?
What is the function of the midbrain in the brain stem?
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Which system is involved in regulating our emotional experiences and expressions?
Which system is involved in regulating our emotional experiences and expressions?
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What is the function of the basal ganglia?
What is the function of the basal ganglia?
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What percentage of all neurons in the central nervous system are found in the cerebral cortex?
What percentage of all neurons in the central nervous system are found in the cerebral cortex?
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What was Charcot's contribution to the field of psychology?
What was Charcot's contribution to the field of psychology?
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What is the term for the release of emotional material that has been made unconscious?
What is the term for the release of emotional material that has been made unconscious?
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What is the function of the thalamus and hypothalamus?
What is the function of the thalamus and hypothalamus?
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What is the name of the genetic defect that causes Huntington's disease?
What is the name of the genetic defect that causes Huntington's disease?
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What is the cerebellum responsible for?
What is the cerebellum responsible for?
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What is the purpose of linkage studies in genetics?
What is the purpose of linkage studies in genetics?
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What is the location of the limbic system?
What is the location of the limbic system?
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What is the result of a genetic defect that causes Phenylketonuria (PKU)?
What is the result of a genetic defect that causes Phenylketonuria (PKU)?
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What is the function of the cerebral cortex?
What is the function of the cerebral cortex?
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What is the relationship between the different dimensions of psychopathology?
What is the relationship between the different dimensions of psychopathology?
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What is the age of onset of Huntington's disease?
What is the age of onset of Huntington's disease?
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What is the focus of an integrative approach to psychopathology?
What is the focus of an integrative approach to psychopathology?
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What is the class of neurotransmitters that dopamine belongs to?
What is the class of neurotransmitters that dopamine belongs to?
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What is the relationship between norepinephrine and states of panic?
What is the relationship between norepinephrine and states of panic?
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What is the effect of reserpine on dopamine activity?
What is the effect of reserpine on dopamine activity?
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What is the relationship between dopamine circuits and serotonin circuits?
What is the relationship between dopamine circuits and serotonin circuits?
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What is the function of norepinephrine in the central nervous system?
What is the function of norepinephrine in the central nervous system?
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What is the relationship between norepinephrine and alpha-adrenergic and beta-adrenergic receptors?
What is the relationship between norepinephrine and alpha-adrenergic and beta-adrenergic receptors?
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What is the implication of dopamine in the pathophysiology of schizophrenia?
What is the implication of dopamine in the pathophysiology of schizophrenia?
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What is the relationship between dopamine and attention deficit hyperactivity disorder (ADHD)?
What is the relationship between dopamine and attention deficit hyperactivity disorder (ADHD)?
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What is the primary characteristic of blood-injection-injury phobias?
What is the primary characteristic of blood-injection-injury phobias?
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What is the approximate age of onset for blood-injection-injury phobias?
What is the approximate age of onset for blood-injection-injury phobias?
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What is the term for phobias that do not fit any of the four major subtypes?
What is the term for phobias that do not fit any of the four major subtypes?
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What is the key difference between situational phobia and panic disorder?
What is the key difference between situational phobia and panic disorder?
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What is the term for fears of situations or events occurring in nature?
What is the term for fears of situations or events occurring in nature?
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What is the peak age of onset for natural environment phobias?
What is the peak age of onset for natural environment phobias?
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What is the requirement for a fear to be considered a phobia?
What is the requirement for a fear to be considered a phobia?
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What is the term for fears of animals or insects?
What is the term for fears of animals or insects?
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What has been approved by the Food and Drug Administration for the treatment of SAD since 1999?
What has been approved by the Food and Drug Administration for the treatment of SAD since 1999?
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What is the characteristic of selective mutism?
What is the characteristic of selective mutism?
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What is the primary advantage of cognitive-behavioral treatment for SAD compared to SSRIs?
What is the primary advantage of cognitive-behavioral treatment for SAD compared to SSRIs?
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What is the effect of adding D-cycloserine (DCS) to cognitive-behavioral treatments for SAD?
What is the effect of adding D-cycloserine (DCS) to cognitive-behavioral treatments for SAD?
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What is the primary focus of DSM-5's consolidation of a group of formerly disparate disorders?
What is the primary focus of DSM-5's consolidation of a group of formerly disparate disorders?
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What is the duration of time required for a diagnosis of selective mutism?
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What is the term for the group of disorders that develop after a relatively stressful or traumatic life event?
What is the term for the group of disorders that develop after a relatively stressful or traumatic life event?
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What is the result of a comparison between Clark's cognitive therapy and the SSRI drug Prozac for the treatment of SAD?
What is the result of a comparison between Clark's cognitive therapy and the SSRI drug Prozac for the treatment of SAD?
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Study Notes
History of Psychiatry
- Asylums originated in the 16th century, but they were more like prisons than hospitals.
- Moral therapy, introduced by Benjamin Rush, made asylums habitable and even therapeutic in Europe and the United States.
- However, humane treatment declined in the mid-19th century due to factors such as overcrowding, making it difficult to provide individual attention.
Dorothea Dix and the Mental Hygiene Movement
- Dorothea Dix, a schoolteacher, campaigned for reform in the treatment of insanity, improving the standards of care and making sure everyone who needed care received it, including the homeless.
- Her efforts led to humane treatment becoming more widely available in U.S. institutions.
Franz Mesmer and Hypnosis
- Franz Mesmer suggested that an undetectable fluid called "animal magnetism" caused problems, which could be blocked.
- Mesmer is widely regarded as the father of hypnosis, a state in which extremely suggestible subjects appear to be in a trance.
The Brain and its Functions
- The left hemisphere is responsible for verbal and cognitive processes, while the right hemisphere is better at perceiving the world and creating images.
- The brain has four lobes: temporal, parietal, occipital, and frontal.
- The temporal lobe is associated with recognizing sights and sounds, and long-term memory storage.
- The parietal lobe is associated with recognizing sensations of touch and monitoring body positioning.
- The occipital lobe is associated with integrating and making sense of visual inputs.
- The frontal lobe is responsible for higher cognitive functions such as thinking, planning, and long-term memory.
The Peripheral Nervous System
- The peripheral nervous system coordinates with the brain stem to ensure the body is working properly.
- Its two major components are the somatic nervous system and the autonomic nervous system.
- The somatic nervous system controls the muscles, while the autonomic nervous system regulates the cardiovascular and endocrine systems, among other functions.
Research Methods
- The placebo effect occurs when behavior changes due to a person's expectation of change, rather than an actual manipulation by an experimenter.
- Comparative treatment research involves comparing different treatments to assess their effectiveness.
- Single-case experimental design involves repeated measurement of a behavior to assess the effect of an independent variable.
- Genetic linkage analysis is used to identify genes responsible for specific disorders by studying the inheritance of genetic markers.
Generalized Anxiety Disorder (GAD)
- About two-thirds of individuals with GAD are female, but this sex ratio may be specific to developed countries.
- Some people with GAD report onset in early adulthood, usually in response to a life stressor.
- The median age of onset is 31.
- GAD is prevalent among older adults, with the highest prevalence in the group over 45 years of age.
Treatment of GAD
- Benzodiazepines are commonly prescribed for GAD, but they can impair cognitive and motor functioning, and lead to physical and psychological dependence.
- Antidepressants such as paroxetine and venlafaxine have stronger evidence for their effectiveness in treating GAD.
- Cognitive-behavioral treatment (CBT) involves confronting anxiety-provoking images and thoughts head-on, and has been shown to be effective in treating GAD.
Obsessive-Compulsive Disorder (OCD)
- In OCD, the dangerous event is a thought, image, or impulse that the client attempts to avoid.
- Obsessions are intrusive and nonsensical thoughts, images, or urges that the individual tries to resist or eliminate.
- Compulsions are the thoughts or actions used to suppress the obsessions and provide relief.
- There are four major types of obsessions, each associated with a pattern of compulsive behavior: symmetry, forbidden thoughts or actions, cleaning and contamination, and hoarding.
Types of Mental Health Professionals
- Counseling psychologists study and treat adjustment and vocational issues in relatively healthy individuals.
- Clinical psychologists focus on more severe psychological disorders.
- Psychiatrists earn an M.D. degree, specialize in psychiatry, and investigate psychological disorders from a biological perspective.
- Psychiatric social workers earn a master's degree in social work, collect information on social and family situations, and treat disorders.
- Psychiatric nurses have advanced degrees, specialize in patient care, and work in hospitals as part of a treatment team.
- Marriage and family therapists and mental health counselors earn a master's degree, provide clinical services, and work under the supervision of a doctoral-level clinician.
Mental Health Professionals' Approach
- Many mental health professionals take a scientific approach to their clinical work, known as scientist-practitioners.
Prevalence of Disorders
- The prevalence of a disorder is the percentage of people in the population who have the disorder.
Dopamine and Serotonin
- Dopamine is associated with exploratory, outgoing, and pleasure-seeking behaviors.
- Serotonin is associated with inhibition and constraint.
- L-dopa is a dopamine agonist that increases dopamine levels.
- Dopamine deficiencies are associated with disorders like Parkinson's disease.
Cognitive Science
- Cognitive science is concerned with how we acquire and process information, store, and retrieve it.
Learned Helplessness
- Learned helplessness occurs when individuals encounter conditions over which they have no control.
- Martin Seligman and Steven Maier described learned helplessness in rats.
Modeling or Observational Learning
- Albert Bandura observed that organisms can learn by observing what happens to someone else in a given situation.
Panic Disorder and Agoraphobia
- Panic disorder is characterized by severe, unexpected panic attacks.
- Agoraphobia is fear and avoidance of situations in which a person feels unsafe or unable to escape.
- Panic disorder and agoraphobia are often integrated into one disorder, but can occur separately.
- Many people who experience panic attacks do not develop panic disorder.
Statistics
- The prevalence of panic disorder is 6.8% in a given 1-year period.
- Panic disorder is more prevalent in adolescents, with a peak age of onset around 13 years.
Social Anxiety Disorder (SAD)
- SAD is the second most prevalent anxiety disorder, affecting over 35 million people in the United States.
- The sex ratio for SAD is nearly 50:50.
- SAD usually begins during adolescence, with a peak age of onset around 13 years.
- SAD is more prevalent in people who are young, undereducated, single, and of low socioeconomic class.
Causes of SAD
- Mogg and colleagues showed that socially anxious individuals more quickly recognize angry faces than "normals".
- Inheritance of a tendency to fear angry faces may have evolved to avoid hostile, angry, or domineering people.
- Jerome Kagan and colleagues demonstrated that some infants are born with a temperamental profile of inhibition or shyness.
Treatment of SAD
- Clark and colleagues evaluated a cognitive therapy program that emphasized real-life experiences during therapy to disprove automatic perceptions of danger.
- This treatment was superior to interpersonal psychotherapy (IPT) both immediately after treatment and at a 1-year follow-up.
Post-Traumatic Stress Disorder (PTSD)
- PTSD cannot be diagnosed until a month after the trauma.
- In PTSD with delayed onset, individuals show few or no symptoms immediately or for months after a trauma, but develop full-blown PTSD at least 6 months later.
Statistics
- The prevalence of PTSD is 6.8% in the population as a whole.
- The highest rates of PTSD are associated with experiences of rape, being held captive, tortured, or kidnapped, or being badly assaulted.
Causes of PTSD
- Intensity of exposure to assaultive violence contributes to the etiology of PTSD, but does not account for all of it.
- A family history of anxiety suggests a generalized biological vulnerability for PTSD.
- Specific characteristics of the serotonin transporter gene may increase the probability of becoming depressed.
Neurotransmitters and Hormones
- The adrenal glands produce the stress hormone cortisol, which is part of the hypothalamic-pituitary-adrenocortical (HPA) axis.
- Neurotransmitters can be studied by introducing agonists, antagonists, or inverse agonists to increase, decrease, or block their activity.
- Reuptake is the process of a neurotransmitter being drawn back into the neuron after release, and some drugs work by blocking this process.
Amino-Acid Neurotransmitters
- Glutamate is an excitatory neurotransmitter that stimulates action.
- Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that regulates the transmission of information and action potentials.
- GABA and glutamate work together to balance brain function, and are referred to as the "chemical brothers".
- GABA has a calming effect and is associated with reducing anxiety.
- Benzodiazepines, such as minor tranquilizers, make it easier for GABA molecules to attach to neuron receptors.
Dopamine and Serotonin
- Dopamine is associated with exploratory, outgoing, and pleasure-seeking behaviors.
- Serotonin is associated with inhibition and constraint, and balances dopamine activity.
- L-dopa is a dopamine agonist that can increase dopamine levels and is used to treat motor disabilities in Parkinson's disease.
- Dopamine and serotonin interact to regulate motor behavior, with dopamine switching on the locomotor system.
Cognitive Science and Learning
- Cognitive science studies how we acquire, process, and store information, and how we retrieve it from memory.
- Learned helplessness occurs when animals or humans encounter conditions they have no control over.
- Observational learning, also known as modeling, occurs when we learn by observing what happens to someone else.
- Prepared learning is the idea that we have evolved to learn about certain types of objects or situations due to their importance for survival.
Anxiety and Related Disorders
- Anxiety is a negative mood state characterized by physical tension and apprehension about the future.
- Fear is an immediate emotional reaction to current danger, characterized by strong escapist action tendencies.
- Panic attacks are abrupt experiences of intense fear or discomfort, accompanied by physical symptoms.
- The limbic system, particularly the behavioral inhibition system (BIS), is involved in anxiety.
- The BIS is activated by signals from the brain stem and cortex, and causes freezing, anxiety, and apprehensive evaluation.
Treatment of Anxiety Disorders
- Exposure-based treatments involve gradually exposing patients to feared situations to learn there is nothing to fear.
- Panic control treatment (PCT) involves exposing patients to physical sensations that remind them of their panic attacks.
- Gradual exposure exercises can be effective in helping patients overcome agoraphobic behavior.
- Psychological treatments, such as CBT, may be more effective in the long run than drug treatment for panic disorder and agoraphobia.
Hypnosis and Catharsis
- Charcot, a distinguished neurologist, demonstrated the effectiveness of mesmerism techniques in treating psychological disorders and legitimized the practice of hypnosis.
- He discovered that recalling and reliving emotional trauma can be therapeutic and lead to emotional release, known as catharsis.
Integrative Approach to Psychopathology
- No influence operates in isolation, and biological, psychological, and developmental factors interact to create a psychological disorder.
- Each dimension is influenced by the others, and they weave together in complex ways to create a psychological disorder.
Biological Factors
- Huntington's disease is a degenerative brain disease that appears in early to middle age, caused by a genetic defect that affects the basal ganglia.
- It causes broad changes in personality, cognitive functioning, and motor behavior, including involuntary shaking or jerkiness.
- Phenylketonuria (PKU) is a disorder that can result in intellectual disability, caused by the inability to metabolize phenylalanine.
- PKU is caused by a single gene defect, with little contribution from other genes or environmental background.
Genetic Factors
- Linkage studies involve studying individuals with the same disorder and shared features to identify the location of a gene contributing to the disorder.
- Recent research suggests that abnormalities in the cerebellum may be associated with autism, although the connection with motor coordination is not clear.
Brain Structure and Function
- The brain stem controls motor coordination, and the midbrain coordinates movement with sensory input and contains parts of the reticular activating system.
- The thalamus and hypothalamus are involved in regulating behavior and emotion, and function primarily as a relay between the forebrain and lower areas of the brain stem.
- The limbic system is located at the base of the forebrain and helps regulate emotional experiences and expressions, learning, and impulse control.
- The limbic system includes structures such as the hippocampus, cingulate gyrus, septum, and amygdala, which are involved in emotional experiences and expressions.
- The basal ganglia are involved in controlling motor activity, and damage to these structures can cause changes in posture or twitching.
Forebrain and Cerebral Cortex
- The cerebral cortex is the largest part of the forebrain and provides distinctly human qualities, allowing us to plan, reason, and create.
- The cerebral cortex contains more than 80% of all neurons in the central nervous system.
Neurotransmitters
- Norepinephrine is a neurotransmitter that stimulates alpha-adrenergic and beta-adrenergic receptors and is involved in regulating behavioral tendencies.
- Dopamine is a major neurotransmitter involved in the pathophysiology of schizophrenia, disorders of addiction, depression, and attention deficit hyperactivity disorder.
- Dopamine circuits merge and cross with serotonin circuits at many points, influencing many of the same behaviors.
Specific Phobias
- Four major subtypes of specific phobias have been identified: blood-injection-injury, situational, natural environment, and animal type.
- A fifth category, "other," includes phobias that do not fit any of the four major subtypes.
- Those with blood-injection-injury phobias have a distinct physiological reaction compared to people with other types of phobia.
Situational Phobias
- Phobias characterized by fear of public transportation or enclosed places are called situational phobias.
- Claustrophobia, a fear of small enclosed places, is a situational phobia.
- The main difference between situational phobia and panic disorder is that people with situational phobia never experience panic attacks outside the context of their phobic object or situation.
Natural Environment Phobias
- Natural environment phobias are characterized by fear of situations or events occurring in nature, such as heights, storms, and water.
- These phobias have a peak age of onset of about 7 years and are not considered phobias if they are only passing fears.
Animal Phobias
- Fears of animals and insects are called animal phobias.
- These fears are common but become phobic only if severe interference with functioning occurs.
Treatment of Social Anxiety Disorder
- Cognitive-behavioral treatment has been shown to be effective in reducing social anxiety in adolescents.
- SSRIs such as Paxil, Zoloft, and Effexor have been approved for the treatment of social anxiety disorder.
- One study found that cognitive therapy was more effective than the SSRI drug Prozac in treating social anxiety disorder.
- Adding the drug D-cycloserine to cognitive-behavioral treatments has been shown to enhance the effects of treatment.
Selective Mutism
- Selective mutism is a rare childhood disorder characterized by a lack of speech in one or more settings in which speaking is socially expected.
- Speech in selective mutism commonly occurs in some settings, such as home, but not others, such as school.
- The lack of speech must occur for more than one month and cannot be limited to the first month of school to meet diagnostic criteria.
Trauma-and Stressor-Related Disorders
- DSM-5 consolidates a group of formerly disparate disorders that all develop after a relatively stressful or traumatic life event.
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