History of Blood Transfusions and Discoveries
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Questions and Answers

Who performed the first recorded successful blood transfusion?

  • Karl Landsteiner
  • Philip Syng Physick
  • William Harvey
  • Richard Lower (correct)
  • Which physician discovered the first three human blood groups?

  • Braxton Hicks
  • Alexis Carrel
  • Reuben Ottenberg
  • Karl Landsteiner (correct)
  • What significant procedure did Alexis Carrel develop?

  • Vein-to-vein anastomosis (correct)
  • Use of anticoagulants
  • Blood typing
  • Universal donor recognition
  • What was a major advancement in blood transfusion made by Reuben Ottenberg?

    <p>Use of crossmatching (C)</p> Signup and view all the answers

    What method did Braxton Hicks introduce to blood transfusion practices?

    <p>Sodium phosphate as anticoagulant (A)</p> Signup and view all the answers

    The first successful blood transfusion was recorded by ______.

    <p>Richard Lower</p> Signup and view all the answers

    Karl Landsteiner discovered the first three human blood groups: A, B, and ______.

    <p>C</p> Signup and view all the answers

    Pope Innocent VII was treated with blood from ______ young men in hopes of curing his ailment.

    <p>three</p> Signup and view all the answers

    Philip Syng Physick performed the first human blood transfusion in ______.

    <p>Philadelphia</p> Signup and view all the answers

    Alexis Carrel devised a method known as ______ to prevent clotting during blood transfusions.

    <p>anastomosis</p> Signup and view all the answers

    Flashcards

    William Harvey

    English physician who discovered the circulation of blood in 1628, paving the way for the understanding of blood transfusions.

    First Successful Blood Transfusion

    The first recorded successful blood transfusion in 1665, performed by Richard Lower in England, who successfully kept dogs alive by transfusions from other dogs.

    Karl Landsteiner

    An Austrian physician who discovered the first three blood groups (A, B, and C, later renamed O) in 1900, revolutionizing blood transfusions and earning him the Nobel Prize in Medicine in 1930.

    First Blood Transfusion with Typing and Crossmatching

    The first blood transfusion using blood typing and crossmatching, performed in New York by Reuben Ottenberg, ensuring compatibility and preventing dangerous reactions.

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    Anastomosis (Direct Vein-to-Artery Connection)

    A method devised by Alexis Carrel in 1908 to prevent blood clotting by directly connecting the recipient's vein to the donor's artery, known as anastomosis.

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    Anastomosis

    This term refers to the direct connection between the recipient's vein and the donor's artery, discovered by Alexis Carrel in 1908 to prevent blood clotting during transfusions.

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    First Transfusion with Typing and Crossmatching

    Dr. Reuben Ottenberg performed the first blood transfusion using blood typing and crossmatching in New York. This ensures compatibility and prevents dangerous reactions.

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    Discovery of Blood Groups

    In 1900, Dr. Karl Landsteiner discovered the three main human blood groups, A, B, and C (later renamed O), which revolutionized blood transfusions and earned him the Nobel Prize in Medicine in 1930.

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    First Human Blood Transfusion

    In 1795, American physician Philip Syng Physick performed the first human blood transfusion in Philadephia.

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    Study Notes

    Early Blood Transfusions and Discoveries

    • 1492: An unsuccessful blood transfusion attempt was made on Pope Innocent VII. Blood from three young men was given to the Pope, resulting in the death of all four.

    • 1628: William Harvey, an English physician, discovered blood circulation. Soon after, the first known blood transfusion attempt occurred.

    • 1665: Richard Lower performed the first recorded successful blood transfusion in England. He kept dogs alive by transfusing blood between dogs.

    • 1795: Philip Syng Physick, an American physician in Philadelphia, performed the first human blood transfusion, but did not publish the details.

    Further Developments in Blood Transfusion and Blood Groups

    • 1869: Braxton Hicks used sodium phosphate as an anticoagulant.

    • 1900: Karl Landsteiner, an Austrian physician, discovered the first three human blood groups (A, B, and C). Blood type C was later reclassified as O. He received the Nobel Prize in Medicine for this discovery in 1930.

    • Circa 1900s: Reuben Ottenberg performed the first blood transfusion using blood typing and crossmatching in New York. He observed Mendelian inheritance of blood groups and recognized group O donors as universal.

    • 1908: Alexis Carrel developed a method to prevent clotting in blood transfusions by directly connecting the recipient's vein to the donor's artery (anastomosis).

    Additional Notes (Genetic Markers)

    • The provided text lists genetic markers for blood group genes (e.g., P003, P1, RH004, RH, etc). These markers indicate the chromosomal location of various blood group genes, but the specific details beyond the chromosomal location are not provided.

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    Description

    Explore the fascinating timeline of blood transfusions, including early attempts, significant discoveries, and groundbreaking advancements in medical science. Learn about key figures like William Harvey and Karl Landsteiner and their contributions to understanding blood circulation and types.

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