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Questions and Answers
Microphotography was already well known before the mid-20th century.
Microphotography was already well known before the mid-20th century.
True (A)
Cells are naturally colorful and opaque, so they do not need to be stained for observation under a microscope.
Cells are naturally colorful and opaque, so they do not need to be stained for observation under a microscope.
False (B)
Camillo Golgi and Santiago Ramon y Cajal shared the Nobel Peace Prize in Physiology or Medicine in 1906 for their work in neuroscience and histology.
Camillo Golgi and Santiago Ramon y Cajal shared the Nobel Peace Prize in Physiology or Medicine in 1906 for their work in neuroscience and histology.
True (A)
The Antoni van Leeuwenhoek microscope was used to observe objects that are very large.
The Antoni van Leeuwenhoek microscope was used to observe objects that are very large.
The development of synthetic dyes for textile industry between 1600 and 1800 did not impact the staining techniques used in histology.
The development of synthetic dyes for textile industry between 1600 and 1800 did not impact the staining techniques used in histology.
The Antoni van Leeuwenhoek microscope was a crude but functional optical instrument used to observe objects that are very small.
The Antoni van Leeuwenhoek microscope was a crude but functional optical instrument used to observe objects that are very small.
Microphotography revolutionized microscopy science before the mid-20th century.
Microphotography revolutionized microscopy science before the mid-20th century.
The development of synthetic dyes between 1600 and 1800 did not impact tissue staining techniques in histology.
The development of synthetic dyes between 1600 and 1800 did not impact tissue staining techniques in histology.
Most cells are naturally colorful and opaque in their original state, making staining unnecessary for observation under a microscope.
Most cells are naturally colorful and opaque in their original state, making staining unnecessary for observation under a microscope.
Histology was first recognized as a medical specialty in 1906 by Camillo Golgi and Santiago Ramon y Cajal's pioneering work in neuroscience.
Histology was first recognized as a medical specialty in 1906 by Camillo Golgi and Santiago Ramon y Cajal's pioneering work in neuroscience.
Understanding the normal structure of tissues is crucial for interpreting changes that occur during exams.
Understanding the normal structure of tissues is crucial for interpreting changes that occur during exams.
Histological techniques allow for the understanding of cell and tissue structure.
Histological techniques allow for the understanding of cell and tissue structure.
Pathology focuses on recognizing the normal appearance of several pathological tissues.
Pathology focuses on recognizing the normal appearance of several pathological tissues.
The development of the cellular doctrine by Theodor Schwann was a key 19th-century histological discovery.
The development of the cellular doctrine by Theodor Schwann was a key 19th-century histological discovery.
Synthetic dyes developed between 1600 and 1800 had no impact on tissue staining techniques in histology.
Synthetic dyes developed between 1600 and 1800 had no impact on tissue staining techniques in histology.
What is the main focus of histopathology?
What is the main focus of histopathology?
Which histological technique is essential for understanding cell and tissue structure?
Which histological technique is essential for understanding cell and tissue structure?
What did Theodor Schwann propose in 1839 that is significant in histological discoveries?
What did Theodor Schwann propose in 1839 that is significant in histological discoveries?
Which type of tissue makes up the organs of the human body?
Which type of tissue makes up the organs of the human body?
In histopathology, what is the primary focus when evaluating cells and tissues?
In histopathology, what is the primary focus when evaluating cells and tissues?
Enzyme histochemistry is the best approach to identify and localize a specific protein within cells.
Enzyme histochemistry is the best approach to identify and localize a specific protein within cells.
In histologic technique, in situ hybridization is used to visualize nucleic acids.
In histologic technique, in situ hybridization is used to visualize nucleic acids.
Immunohistochemistry is a technique that uses antibodies to detect specific proteins in cells or tissues.
Immunohistochemistry is a technique that uses antibodies to detect specific proteins in cells or tissues.
FISH can be used to detect the t(9;22) translocation in leukemia patients.
FISH can be used to detect the t(9;22) translocation in leukemia patients.
Biopsy samples are often analyzed using histochemical techniques to study tissue structure.
Biopsy samples are often analyzed using histochemical techniques to study tissue structure.
Immunohistochemistry can be used to detect and localize specific proteins in cells or tissues.
Immunohistochemistry can be used to detect and localize specific proteins in cells or tissues.
Prussian blue stain is commonly used to detect iron in tissues during histological examinations.
Prussian blue stain is commonly used to detect iron in tissues during histological examinations.
Biopsy samples are not often analyzed using ancillary tests like molecular studies or flow cytometry.
Biopsy samples are not often analyzed using ancillary tests like molecular studies or flow cytometry.
The source of tissue for cytologic assessment during histological examinations is primarily bone marrow smear aspiration.
The source of tissue for cytologic assessment during histological examinations is primarily bone marrow smear aspiration.
In situ hybridization involves directly applying nucleic acid sequences to prepared cells and tissue sections.
In situ hybridization involves directly applying nucleic acid sequences to prepared cells and tissue sections.
What is the study of cells called?
What is the study of cells called?
Which component of a cell serves as the structural framework?
Which component of a cell serves as the structural framework?
What is the fluid component of the cell called?
What is the fluid component of the cell called?
Which type of tissue is responsible for covering body surfaces and lining body cavities?
Which type of tissue is responsible for covering body surfaces and lining body cavities?
Which tissue mainly consists of cells that perform the main function of an organ?
Which tissue mainly consists of cells that perform the main function of an organ?
Which immunocytochemistry method uses a labeled secondary antibody?
Which immunocytochemistry method uses a labeled secondary antibody?
What type of label is directly attached to the antibody in direct immunocytochemistry?
What type of label is directly attached to the antibody in direct immunocytochemistry?
How is the protein of interest on the tissue section visualized in direct immunocytochemistry?
How is the protein of interest on the tissue section visualized in direct immunocytochemistry?
What is the key feature of indirect immunocytochemistry that contributes to the amplification of protein labeling?
What is the key feature of indirect immunocytochemistry that contributes to the amplification of protein labeling?
What role does the secondary antibody play in indirect immunocytochemistry?
What role does the secondary antibody play in indirect immunocytochemistry?
Direct immunocytochemistry uses a labeled primary antibody to bind specifically to the tissue protein of interest.
Direct immunocytochemistry uses a labeled primary antibody to bind specifically to the tissue protein of interest.
Indirect immunocytochemistry amplifies the labeling of the protein of interest due to the ability of one labeled secondary antibody to bind multiple primary antibodies.
Indirect immunocytochemistry amplifies the labeling of the protein of interest due to the ability of one labeled secondary antibody to bind multiple primary antibodies.
Indirect immunocytochemistry uses a secondary antibody made in the same species as the primary antibody against the tissue protein.
Indirect immunocytochemistry uses a secondary antibody made in the same species as the primary antibody against the tissue protein.
Direct immunocytochemistry involves applying a secondary antibody labeled with a fluorescent compound or peroxidase to bind to the tissue protein of interest.
Direct immunocytochemistry involves applying a secondary antibody labeled with a fluorescent compound or peroxidase to bind to the tissue protein of interest.
In indirect immunocytochemistry, the primary antibody binds directly to the specific antigen of interest on the tissue section.
In indirect immunocytochemistry, the primary antibody binds directly to the specific antigen of interest on the tissue section.
Heat fixation is primarily used for preserving the internal structures of single-cell organisms like bacteria and archaea.
Heat fixation is primarily used for preserving the internal structures of single-cell organisms like bacteria and archaea.
Freezing samples for fixation allows for the formation of ice crystals, which helps in preserving the sample's morphology.
Freezing samples for fixation allows for the formation of ice crystals, which helps in preserving the sample's morphology.
Chemical fixation aims to preserve the tissues as close to living tissue as possible by making them soluble in the fixative.
Chemical fixation aims to preserve the tissues as close to living tissue as possible by making them soluble in the fixative.
Fixatives increase the mechanical strength of cells and tissues by altering them on a molecular level.
Fixatives increase the mechanical strength of cells and tissues by altering them on a molecular level.
Fixatives are primarily used to enhance the growth of microorganisms in tissue samples.
Fixatives are primarily used to enhance the growth of microorganisms in tissue samples.
What is the purpose of fixative in cell culture?
What is the purpose of fixative in cell culture?
Which technique is used for fixing single-cell organisms like bacteria and archaea?
Which technique is used for fixing single-cell organisms like bacteria and archaea?
What does freezing samples for fixation achieve in cell culture?
What does freezing samples for fixation achieve in cell culture?
How does chemical fixation differ from heat fixation in preserving samples?
How does chemical fixation differ from heat fixation in preserving samples?
Why is chemical fixation essential for preserving cell structures?
Why is chemical fixation essential for preserving cell structures?
Match the following factors with their influence on staining dye affinity to the target tissue specimen:
Match the following factors with their influence on staining dye affinity to the target tissue specimen:
Match the following statements about indirect immunocytochemistry:
Match the following statements about indirect immunocytochemistry:
Match the following techniques with their applications in histology:
Match the following techniques with their applications in histology:
Match the following terms with their relevance to cell culture:
Match the following terms with their relevance to cell culture:
Match the following features with their description in immunocytochemistry methods:
Match the following features with their description in immunocytochemistry methods:
Match the staining component with its function in Leishman stain:
Match the staining component with its function in Leishman stain:
Match the blood cell type with its characteristic stain color in Leishman stain:
Match the blood cell type with its characteristic stain color in Leishman stain:
Match the staining tip with its recommendation for making a blood smear:
Match the staining tip with its recommendation for making a blood smear:
Match the histological technique with its purpose:
Match the histological technique with its purpose:
Match the staining method with its target cellular component:
Match the staining method with its target cellular component: