Histology of the Intestinal Tract

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Questions and Answers

Which type of epithelial cells primarily covers the intestinal villi?

  • Stratified squamous cells
  • Simple cuboidal cells
  • Simple columnar absorptive cells (correct)
  • Transitional epithelium

What is a prominent type of gland found in the duodenum that secretes alkaline mucus?

  • Parotid gland
  • Brunner's gland (correct)
  • Submandibular gland
  • Sublingual gland

Which part of the large intestine is characterized by the absence of Peyer's patches?

  • Ascending colon (correct)
  • Cecum
  • Transverse colon
  • Ileum

What differentiates the muscularis mucosa of the large intestine from that of the small intestine?

<p>Presence of three bundles known as taeniae coli (B)</p> Signup and view all the answers

How does the lamina propria of the large intestine differ from that of the small intestine?

<p>It is less dense in lymphatic nodules (C)</p> Signup and view all the answers

What type of glands is characterized by having both fundic and pyloric regions?

<p>Gastric glands (D)</p> Signup and view all the answers

Which structure is associated with the absorptive surface of the duodenum?

<p>Leaf shaped villi (B)</p> Signup and view all the answers

What is a significant feature of the villi in the large intestine?

<p>Crypts filled with goblet cells (C)</p> Signup and view all the answers

What type of villi is found in the ileum that is associated with Payer's patches?

<p>Finger like villi with many goblet cells (D)</p> Signup and view all the answers

Which gland primarily does not have any villi in its structural design?

<p>Pancreas (D)</p> Signup and view all the answers

Which type of goblet cell distribution is least prominent in the duodenum?

<p>Few goblet cells (D)</p> Signup and view all the answers

How do the villi in the small intestine differ from those in the large intestine?

<p>Small intestine has villi that enhance absorption, large intestine lacks villi (C)</p> Signup and view all the answers

What structural feature is primarily lacking in the large intestine compared to the small intestine?

<p>Villi (B)</p> Signup and view all the answers

Which type of salivary gland is located beneath the mandible?

<p>Submandibular (B)</p> Signup and view all the answers

What percentage of pancreatic cells are beta cells, which are responsible for insulin production?

<p>70% (D)</p> Signup and view all the answers

What type of blood supply delivers oxygen-rich blood to the liver?

<p>Hepatic artery (B)</p> Signup and view all the answers

Which cells in the liver are specialized macrophages involved in immune response?

<p>Kupffer cells (D)</p> Signup and view all the answers

Which of the following is NOT a function associated with hepatocytes?

<p>Insulin secretion (B)</p> Signup and view all the answers

What structural feature do hepatocytes have that projects into the space of Disse?

<p>Long microvilli (B)</p> Signup and view all the answers

Which cellular organelle is abundant in hepatocytes for the purpose of detoxification?

<p>Smooth endoplasmic reticulum (D)</p> Signup and view all the answers

Which type of blood is primarily rich in nutrients but low in oxygen as it enters the liver?

<p>Portal vein blood (B)</p> Signup and view all the answers

What is the primary function of the muscularis mucosa in the digestive tract?

<p>Propels contents through the digestive tract (B)</p> Signup and view all the answers

Which cells in the stomach are responsible for secreting hydrochloric acid?

<p>Parietal cells (D)</p> Signup and view all the answers

What type of epithelial cells primarily make up the mucosa of the stomach?

<p>Simple columnar (A)</p> Signup and view all the answers

In which region of the stomach would you find pyloric glands?

<p>Pyloric region (C)</p> Signup and view all the answers

Which layer of the digestive tract wall contains loose connective tissue and mucous glands in the duodenum and esophagus?

<p>Submucosa (C)</p> Signup and view all the answers

What are the three layers composing the musculosa of the stomach?

<p>Inner oblique, middle circular, outer longitudinal (D)</p> Signup and view all the answers

Which part of the small intestine is primarily responsible for the complete digestion of food?

<p>Jejunum (D)</p> Signup and view all the answers

Which of the following correctly describes the serosa of the digestive tract?

<p>It is covered by a layer of mesothelium (C)</p> Signup and view all the answers

Flashcards

Oral cavity

The initial part of the digestive tract, responsible for chewing and mechanical breakdown of food.

Mucosa

A layer of the digestive tract wall that contains epithelial lining, lamina propria, and muscularis mucosa.

Submucosa

A layer of the digestive tract wall consisting of loose connective tissue that contains blood vessels and nerves.

Musculosa

A layer of the digestive tract wall composed of smooth muscle tissue, responsible for peristaltic movement.

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Serosa

A layer of the digestive tract wall that covers the external surface and consists of loose connective tissue and mesothelium.

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Cardiac region of the stomach

The region of the stomach surrounding the esophageal orifice.

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Fundus and body of the stomach

The main part of the stomach, responsible for storing and mixing food with gastric juices.

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Pylorus of the stomach

The termination of the stomach, connecting to the small intestine.

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Enterocytes

Tall, cylindrical cells lining the intestinal villi, responsible for absorbing nutrients.

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Goblet cells

Specialized cells within the intestinal epithelium that secrete mucus, lubricating the gut and protecting it from damage.

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Enteroendocrine cells

Cells scattered throughout the intestinal epithelium, responsible for producing hormones that regulate digestion.

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Serosa of the large intestine

The outermost layer of the large intestine wall, composed of connective tissue covered by a single layer of epithelial cells.

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Taeniae coli

Three bands of longitudinal smooth muscle that run along the length of the large intestine, responsible for its characteristic segmentation and contractions.

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Gastric glands

Tiny, tube-shaped structures in the stomach lining responsible for secreting gastric juices, including hydrochloric acid and pepsinogen.

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Fundic glands

A type of gastric gland found in the fundus and body of the stomach, primarily responsible for secreting pepsinogen, a precursor to the enzyme pepsin.

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Pyloric glands

A type of gastric gland located in the pyloric region of the stomach, mainly responsible for secreting gastrin, a hormone that stimulates gastric acid production.

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Duodenal villi

Small, finger-like projections that increase the surface area for absorption in the duodenum, a part of the small intestine.

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Finger-like villi

Finger-like projections in the small intestine, particularly numerous in the jejunum and ileum, increasing surface area for absorption.

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Payer's patches

Specialized structures found in the small intestine, specifically Peyer's patches, composed of lymphatic tissue that helps in immune function.

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Crypts of Lieberkuhn

Small pits or indentations in the lining of the large intestine, containing mostly goblet cells that produce mucus for lubrication and waste transport.

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What is the Parotid gland?

The largest salivary gland, located in the cheek near the ear.

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What do Beta cells produce?

The pancreatic cells that produce insulin, making up around 70% of the islet cells.

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What are hepatocytes?

The main functional cells of the liver, responsible for essential tasks including protein synthesis, bile production, and detoxification.

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What are microvilli on hepatocytes?

Finger-like projections on hepatocytes that increase surface area for exchange with the blood.

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What are Kupffer cells?

Specialized macrophages found in the liver, responsible for clearing debris and pathogens from the blood.

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What is the space of Disse?

The space between hepatocytes and blood sinusoids, containing reticular fibers and microvilli.

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What is the primary function of the liver?

The primary function of the liver is to detoxify the blood.

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How is the liver supplied with blood?

Blood from the digestive tract flows through the portal vein, delivering nutrients to the liver, while oxygen-rich blood comes from the hepatic artery.

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Study Notes

Digestive System Overview

  • The digestive system is a complex process with multiple organs working together to break down food and absorb nutrients.
  • It involves two main parts: the digestive tract and accessory organs.

Digestive Tract

  • The digestive tract is a long muscular tube beginning at the mouth and ending at the anus.
  • It includes the oral cavity, oropharynx, esophagus, stomach, small intestine, large intestine, rectum, and anal canal.
  • The structure of the digestive tract wall has four layers: mucosa, submucosa, muscularis, and serosa (or adventitia).

Accessory Organs

  • Salivary glands, pancreas, liver, and gall bladder are accessory organs supporting digestion.
  • They produce secretions (like enzymes) that aid in the breakdown, neutralization, and absorption of food.

Oesophagus

  • A long, muscular tube extending from the pharynx to the stomach.
  • Its primary function is to transport food from the mouth to the stomach.
  • The wall of the esophagus is composed of stratified non-keratinized squamous epithelium.

Stomach

  • Divided into cardiac, fundus/body, and pyloric regions.
  • Histologically, the stomach has three layers of muscle: inner oblique, middle circular, and outer longitudinal.
  • The mucosa contains rugae and pits with specialized cells secreting mucus to protect the stomach from its own acidity.

Small Intestine

  • Responsible for the completion of digestion and absorption of nutrients.
  • Composed of three segments: duodenum, jejunum, and ileum.
  • The mucosal lining of the small intestine has villi and crypts for efficient absorption.

Large Intestine

  • Concentrates leftover material from digestion, primarily absorbs water and salts.
  • Segments include cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and rectum.

Salivary Glands

  • Produce saliva in the oral cavity.
  • Saliva aids in lubrication, digestion, and immunity.
  • Divided into major (parotid, submandibular, sublingual) and minor salivary glands.

Pancreas

  • A mixed exocrine and endocrine gland.
  • Exocrine function: produces pancreatic juice (enzymes) for digestion.
  • Endocrine function: produces hormones (such as insulin and glucagon) regulating blood sugar.
  • Contains acini (exocrine) and islets of Langerhans cells (endocrine)

Liver

  • The body's largest metabolic organ.
  • Involved in a wide range of metabolic activities, including bile production and the detoxification of substances.
  • Blood supply to the liver comes primarily from the portal vein and hepatic artery.
  • Hepatocytes are the major functional cells in the liver, responsible for many metabolic functions.

Hepatic Lobules

  • The liver is organized into lobules, each containing a central vein, surrounded by radiating hepatocyte cords, and thin connective tissue.
  • Portal tracts contain the branches of the hepatic portal vein, hepatic artery, and bile ducts.
  • The space of Disse (perisinusoidal space) is a space between the hepatocytes and the blood sinusoids containing blood plasma and lipocytes.

Von Kupffer Cells

  • Phagocytic cells lining the liver sinusoids, removing microbes and cellular debris.

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