Histology of Lymphoid Organs

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60 Questions

Which lymphoid organ is responsible for inducing central tolerance and preventing autoimmunity?

Thymus

What is the main function of the spleen?

Blood filtration

Which lymphoid organ has lymphoid nodules with germinal centers in both the cortex and medulla?

MALT

Which lymphoid organ has a cortex rich in B cells organized around follicular dendritic cells?

Lymph Nodes

Which lymphoid organ has a periarteriolar lymphoid sheath (PALS) surrounding a central arteriole?

Thymus

Which lymphoid organ has a red pulp and a white pulp?

Spleen

Which lymphoid organ has a subcapsular sinus that receives lymph from afferent lymphatics?

Lymph Nodes

Which lymphoid organ has reticular fiber stroma to support lymphocytes, plasma cells, dendritic cells, macrophages, and other APCs?

Lymph Nodes

Which lymphoid organ has a medulla that contains medullary cords and medullary sinuses?

Lymph Nodes

Which lymphoid organ has a blood-thymus barrier and a corticomedullary barrier to prevent exposure of thymocytes to antigens?

Thymus

Which of the following is NOT a key component of the immune system?

Tonsils

Which lymphoid organ is responsible for the production and maturation of T cells?

Thymus

What is the function of lymph nodes?

Filtration of lymph

Which lymphoid organ is the largest in the human body?

Spleen

Which non-encapsulated collection of lymphoid tissue is located in the appendix?

Peyer's patches

What is the function of the thymus?

Maturation of T cells

Which lymphoid organ is NOT encapsulated?

Tonsils

Which lymphoid organ is responsible for the filtration of blood?

Spleen

Which non-encapsulated collection of lymphoid tissue is located in the lining of the small intestine?

Peyer's patches

Which lymphoid organ is responsible for the production of antibodies?

Spleen

Which type of immunity develops slowly and is based on antigens being presented to lymphocytes in blood, lymph, epithelia, and connective tissues?

Adaptive immunity

Which lymphoid organ is responsible for the development of T lymphocytes?

Thymus

Which type of immunity involves physical barriers such as skin and mucous membranes to prevent infections or penetration of the host body?

Innate immunity

Which type of cells destroy unhealthy host cells in innate immunity?

Natural killer cells

Which type of immunity produces memory cells that allow a rapid response upon re-exposure to the same specific microbe?

Adaptive immunity

Which type of cells are responsible for eliminating antigens in the cellular response of adaptive immunity?

T lymphocytes

Which type of cells are responsible for producing antibodies in the humoral response of adaptive immunity?

B lymphocytes

Which protein complex on the surface of antigen-presenting cells is responsible for presenting antigens to T cells?

MHC Class II

Which type of lymphocytes assist with immune responses by producing cytokines to promote B cell differentiation, activate macrophages, and cytotoxic T lymphocytes?

Helper T cells (CD4)

Where do we find lymphocytes?

All of the above

Which lymphoid organ has a blood-thymus barrier and a corticomedullary barrier to prevent exposure of thymocytes to antigens?

Thymus

Which lymphoid organ is responsible for the filtration of blood?

Spleen

Which lymphoid organ has a cortex rich in B cells organized around follicular dendritic cells?

Lymph Nodes

Which non-encapsulated collection of lymphoid tissue is located in the lining of the small intestine?

Peyer's Patches

Which lymphoid organ has a medulla that contains medullary cords and medullary sinuses?

Lymph Nodes

Which lymphoid organ is responsible for the production and maturation of T cells?

Thymus

Which lymphoid organ has a periarteriolar lymphoid sheath (PALS) surrounding a central arteriole?

Thymus

Which lymphoid organ is responsible for the development of T lymphocytes?

Thymus

Which lymphoid organ is responsible for the production of antibodies?

Spleen

Which lymphoid organ is NOT encapsulated?

Tonsils

Which lymphoid organ develops from endoderm?

Thymus

Which lymphoid organ induces central tolerance and prevents autoimmunity?

Thymus

Which lymphoid organ is responsible for the production and maturation of T cells?

Thymus

Which lymphoid organ has a cortex rich in B cells organized around follicular dendritic cells?

Lymph Nodes

Which lymphoid organ is NOT encapsulated?

MALT

Which lymphoid organ has a blood-thymus barrier and a corticomedullary barrier to prevent exposure of thymocytes to antigens?

Thymus

Which lymphoid organ has a medulla that contains medullary cords and medullary sinuses?

Lymph Nodes

Which lymphoid organ has a subcapsular sinus that receives lymph from afferent lymphatics?

Lymph Nodes

Which lymphoid organ has reticular fiber stroma to support lymphocytes, plasma cells, dendritic cells, macrophages, and other APCs?

Spleen

Which lymphoid organ has a periarteriolar lymphoid sheath (PALS) surrounding a central arteriole?

Spleen

Which type of lymphocytes are responsible for eliminating antigens in the cellular response of adaptive immunity?

T lymphocytes

What is the function of the thymus?

Development and maturation of T cells

Which lymphoid organ has a red pulp and a white pulp?

Spleen

What is the function of lymph nodes?

Filtration of lymph

Which type of immunity produces memory cells that allow a rapid response upon re-exposure to the same specific microbe?

Adaptive immunity

Which lymphoid organ has reticular fiber stroma to support lymphocytes, plasma cells, dendritic cells, macrophages, and other antigen-presenting cells (APCs)?

Lymph nodes

Which lymphoid organ has a subcapsular sinus that receives lymph from afferent lymphatics?

Lymph nodes

Which protein complex on the surface of antigen-presenting cells is responsible for presenting antigens to T cells?

Major Histocompatibility Complex (MHC)

Which type of immunity develops slowly and is based on antigens being presented to lymphocytes in blood, lymph, epithelia, and connective tissues?

Adaptive immunity

Which type of immunity involves physical barriers such as skin and mucous membranes to prevent infections or penetration of the host body?

Innate immunity

Test your knowledge of the histology of lymphoid organs with this quiz! Explore the cellular organization and functions of the thymus, as well as the structural architecture and cellular composition of lymph nodes. Gain a deeper understanding of the immune system and lymph and blood circulation. Created by experts in the field, this quiz is perfect for students and professionals in the medical and biological sciences.

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