Connective Tissue Disease, Vasculitis and Related Disorders
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Questions and Answers

What is the first-line treatment for mild to moderate cutaneous involvement in vasculitis?

  • Systemic corticosteroids
  • Anticoagulation therapy
  • Underlying cause treatment
  • Potent topical steroids (correct)
  • Which of the following autoimmune diseases is Raynaud's phenomenon most commonly associated with?

  • Rheumatoid arthritis
  • Systemic sclerosis (correct)
  • Psoriasis
  • Osteoarthritis
  • What is the most common symptom of Raynaud's phenomenon immediately following exposure to cold?

  • Swelling
  • Numbness
  • Color change (correct)
  • Pain
  • In persistent cases of cutaneous vasculitis, what type of medication may be needed as an alternative to corticosteroids?

    <p>Immunosuppressants</p> Signup and view all the answers

    What distinguishes primary Raynaud's phenomenon from secondary Raynaud's phenomenon?

    <p>Symmetry of symptoms</p> Signup and view all the answers

    Which of the following is NOT a symptom of Raynaud's phenomenon?

    <p>Itching</p> Signup and view all the answers

    What is the most common skin involvement seen in systemic lupus erythematosus (SLE) patients?

    <p>Erythematous 'butterfly' distribution rash on the face</p> Signup and view all the answers

    Which of the following drugs has been known to trigger Systemic Lupus Erythematosus (SLE)?

    <p>Chlorpromazine</p> Signup and view all the answers

    What is a diagnostic criterion for Systemic Lupus Erythematosus (SLE)?

    <p>Malar rash</p> Signup and view all the answers

    What type of skin eruption is typically seen in Subacute Lupus Erythematosus?

    <p>Erythematous annular and serpiginous eruption</p> Signup and view all the answers

    Which of the following is a common manifestation of neonatal lupus erythematosus?

    <p>Skin rash</p> Signup and view all the answers

    What treatment is usually required for Systemic Lupus Erythematosus (SLE) with organ involvement?

    <p>Prednisolone</p> Signup and view all the answers

    'Butterfly rash' is associated with which type of Lupus?

    <p><em>Systemic Lupus erythematosus (SLE)</em></p> Signup and view all the answers

    What is the main skin manifestation seen in dermatomyositis affecting the fingers?

    <p>Purplish papules</p> Signup and view all the answers

    Which antibody may be detected in dermatomyositis?

    <p>Anti-Jo-1 antibody</p> Signup and view all the answers

    What type of muscle involvement is typically seen in dermatomyositis?

    <p>Proximal limb weakness</p> Signup and view all the answers

    Which treatment option can help achieve rapid control of symptoms in dermatomyositis?

    <p>Pulsed cyclophosphamide</p> Signup and view all the answers

    What is the characteristic feature usually seen in mixed connective tissue disease (MCTD) involving the hands?

    <p>Sclerodactyly/swollen hands</p> Signup and view all the answers

    Which condition is characterized by overlapping features of SLE, scleroderma, and myositis?

    <p>Mixed connective tissue disease (MCTD)</p> Signup and view all the answers

    In systemic sclerosis (SSc), which diagnostic test is most commonly elevated in patients?

    <p>ANA</p> Signup and view all the answers

    What is a characteristic symptom seen in CREST syndrome?

    <p>Calcinosis Cutis</p> Signup and view all the answers

    Which investigation is specifically recommended for diagnosing CREST syndrome?

    <p>Anticentromere antibodies</p> Signup and view all the answers

    What is the key feature of Morphaea, a benign form of localized systemic sclerosis?

    <p>Localized sclerosis with slight inflammation</p> Signup and view all the answers

    Which condition mainly affects the genital and perineal regions in women and is described as an itchy eruption?

    <p>Lichen Sclerosus</p> Signup and view all the answers

    Which treatment is specifically mentioned for managing sclerodactyly in systemic sclerosis (SSc)?

    <p>Calcitriol</p> Signup and view all the answers

    What is the first symptom typically observed in CREST syndrome?

    <p>Raynaud's phenomenon</p> Signup and view all the answers

    What is the distinctive color of the atrophic patches and plaques seen in Lichen Sclerosus?

    <p>Ivory-white</p> Signup and view all the answers

    Which condition may rarely be associated with the development of squamous cell carcinoma in adults?

    <p>Lichen Sclerosus</p> Signup and view all the answers

    In Lichen Planus, what is the term used to describe the shiny purple-colored flat-topped papules in the 6 Ps mnemonic?

    <p>Polygonal</p> Signup and view all the answers

    Which skin condition is characterized by the presence of Wickham’s striae on the surface of lesions?

    <p>Lichen Planus</p> Signup and view all the answers

    What is the main underlying cause of Lichen Planus?

    <p>Unknown etiology</p> Signup and view all the answers

    In which type of skin, Lichen Planus may present as very hypertrophic and heal with marked hyperpigmentation?

    <p>Black skin</p> Signup and view all the answers

    Which condition is characterized by fibrosis of the underlying tissues and loss of normal genital architecture?

    <p>Lichen Sclerosus</p> Signup and view all the answers

    'Koebner phenomenon' is associated with which skin condition presenting as lesions in linear scratches or surgical scars?

    <p>Lichen Planus</p> Signup and view all the answers

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