Connective Tissue Disease, Vasculitis and Related Disorders
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Questions and Answers

What is the first-line treatment for mild to moderate cutaneous involvement in vasculitis?

  • Systemic corticosteroids
  • Anticoagulation therapy
  • Underlying cause treatment
  • Potent topical steroids (correct)

Which of the following autoimmune diseases is Raynaud's phenomenon most commonly associated with?

  • Rheumatoid arthritis
  • Systemic sclerosis (correct)
  • Psoriasis
  • Osteoarthritis

What is the most common symptom of Raynaud's phenomenon immediately following exposure to cold?

  • Swelling
  • Numbness
  • Color change (correct)
  • Pain

In persistent cases of cutaneous vasculitis, what type of medication may be needed as an alternative to corticosteroids?

<p>Immunosuppressants (C)</p> Signup and view all the answers

What distinguishes primary Raynaud's phenomenon from secondary Raynaud's phenomenon?

<p>Symmetry of symptoms (C)</p> Signup and view all the answers

Which of the following is NOT a symptom of Raynaud's phenomenon?

<p>Itching (D)</p> Signup and view all the answers

What is the most common skin involvement seen in systemic lupus erythematosus (SLE) patients?

<p>Erythematous 'butterfly' distribution rash on the face (A)</p> Signup and view all the answers

Which of the following drugs has been known to trigger Systemic Lupus Erythematosus (SLE)?

<p>Chlorpromazine (A)</p> Signup and view all the answers

What is a diagnostic criterion for Systemic Lupus Erythematosus (SLE)?

<p>Malar rash (B)</p> Signup and view all the answers

What type of skin eruption is typically seen in Subacute Lupus Erythematosus?

<p>Erythematous annular and serpiginous eruption (A)</p> Signup and view all the answers

Which of the following is a common manifestation of neonatal lupus erythematosus?

<p>Skin rash (C)</p> Signup and view all the answers

What treatment is usually required for Systemic Lupus Erythematosus (SLE) with organ involvement?

<p>Prednisolone (A)</p> Signup and view all the answers

'Butterfly rash' is associated with which type of Lupus?

<p><em>Systemic Lupus erythematosus (SLE)</em> (C)</p> Signup and view all the answers

What is the main skin manifestation seen in dermatomyositis affecting the fingers?

<p>Purplish papules (A)</p> Signup and view all the answers

Which antibody may be detected in dermatomyositis?

<p>Anti-Jo-1 antibody (A)</p> Signup and view all the answers

What type of muscle involvement is typically seen in dermatomyositis?

<p>Proximal limb weakness (C)</p> Signup and view all the answers

Which treatment option can help achieve rapid control of symptoms in dermatomyositis?

<p>Pulsed cyclophosphamide (B)</p> Signup and view all the answers

What is the characteristic feature usually seen in mixed connective tissue disease (MCTD) involving the hands?

<p>Sclerodactyly/swollen hands (C)</p> Signup and view all the answers

Which condition is characterized by overlapping features of SLE, scleroderma, and myositis?

<p>Mixed connective tissue disease (MCTD) (C)</p> Signup and view all the answers

In systemic sclerosis (SSc), which diagnostic test is most commonly elevated in patients?

<p>ANA (C)</p> Signup and view all the answers

What is a characteristic symptom seen in CREST syndrome?

<p>Calcinosis Cutis (A)</p> Signup and view all the answers

Which investigation is specifically recommended for diagnosing CREST syndrome?

<p>Anticentromere antibodies (A)</p> Signup and view all the answers

What is the key feature of Morphaea, a benign form of localized systemic sclerosis?

<p>Localized sclerosis with slight inflammation (A)</p> Signup and view all the answers

Which condition mainly affects the genital and perineal regions in women and is described as an itchy eruption?

<p>Lichen Sclerosus (C)</p> Signup and view all the answers

Which treatment is specifically mentioned for managing sclerodactyly in systemic sclerosis (SSc)?

<p>Calcitriol (A)</p> Signup and view all the answers

What is the first symptom typically observed in CREST syndrome?

<p>Raynaud's phenomenon (C)</p> Signup and view all the answers

What is the distinctive color of the atrophic patches and plaques seen in Lichen Sclerosus?

<p>Ivory-white (B)</p> Signup and view all the answers

Which condition may rarely be associated with the development of squamous cell carcinoma in adults?

<p>Lichen Sclerosus (B)</p> Signup and view all the answers

In Lichen Planus, what is the term used to describe the shiny purple-colored flat-topped papules in the 6 Ps mnemonic?

<p>Polygonal (D)</p> Signup and view all the answers

Which skin condition is characterized by the presence of Wickham’s striae on the surface of lesions?

<p>Lichen Planus (C)</p> Signup and view all the answers

What is the main underlying cause of Lichen Planus?

<p>Unknown etiology (D)</p> Signup and view all the answers

In which type of skin, Lichen Planus may present as very hypertrophic and heal with marked hyperpigmentation?

<p>Black skin (A)</p> Signup and view all the answers

Which condition is characterized by fibrosis of the underlying tissues and loss of normal genital architecture?

<p>Lichen Sclerosus (A)</p> Signup and view all the answers

'Koebner phenomenon' is associated with which skin condition presenting as lesions in linear scratches or surgical scars?

<p>Lichen Planus (D)</p> Signup and view all the answers

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