18 Questions
What type of discharge is typically produced in Trichomonas vaginalis infection?
Watery, copious gray-green discharge
Which age group is commonly affected by squamous cell carcinoma of the vagina?
Women older than 60 years
What is the precursor lesion nearly always associated with HPV infection?
Vaginal intraepithelial neoplasia (VAIN)
In which group of women was clear cell adenocarcinoma identified due to maternal exposure to diethylstilbestrol DES during pregnancy?
A cluster of young women whose mothers took DES during pregnancy
Which type of primary vaginal cancer is usually encountered in infants and children younger than 5 years of age?
Sarcoma botryoides
What benign lesions are seen in the vaginal mucosa of about one third of women exposed to diethylstilbestrol DES during pregnancy?
Red, granular-appearing foci lined by mucus-secreting or ciliated columnar cells
What is the most common cause of vulvitis?
Human papillomavirus (HPV)
Which condition is characterized by thinning of the epidermis and appearance of smooth, white plaques?
Lichen Sclerosus
What sexually transmitted infection can cause a suppurative infection of the vulvovaginal glands?
N.gonorrhoeae
Which pathogen is associated with the primary chancre at a vulvar site of inoculation?
Treponema pallidum
What is the characteristic feature of herpes simplex virus (HSV-1 or -2) infection in the vulva?
Vesicular eruption
Which infection is NOT sexually transmitted but can cause vulvitis?
Candida
What is the most common condition associated with the production of a vaginal discharge?
Vaginitis
What organisms are frequently associated with vaginitis?
Candida albicans and Trichomonas vaginalis
Which condition is characterized by a curdy white discharge?
Candidal vaginitis
What are some predisposing influences that can lead to symptomatic infection with Candida albicans?
Diabetes, systemic antibiotic therapy, immunodeficiency, pregnancy, or recent abortion
What are some examples of congenital anomalies of the vagina?
Total absence of the vagina, a septate or double vagina
What is the primary source of disease in the vagina?
Cancer or infections arising in adjacent organs (e.g., cervix, vulva, bladder, rectum)
Explore histologic examination findings of large cells with pale, granular cytoplasm infiltrating the epidermis in diseases affecting the vagina, either as a primary or secondary site. Learn about congenital anomalies and other conditions involving the vagina.
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