25 Questions
What is the most common type of malignant tumor involving bone?
Metastatic tumors
Which of the following is not a common site of metastatic bone tumors in adults?
Brain
What is the typical radiographic appearance of a giant cell tumor (GCT)?
Purely lytic and eccentric, with destruction of the overlying cortex
Which of the following is the most common clinical presentation of a giant cell tumor (GCT)?
Pain and fractures
Which of the following is a characteristic of giant cell tumors (GCTs)?
They are considered benign, but have a high rate of local recurrence
What is the most frequent location for Osteoma in the body?
Proximal femur and tibia
Which tumor presents with localized pain that is severe at night and is typically responsive to aspirin?
Osteoid Osteoma
What distinguishes Osteoblastomas from Osteoid Osteomas in terms of size and clinical features?
Osteoblastomas are larger and may not be responsive to aspirin for pain relief.
Which bone tumor is characterized by interlacing trabeculae of woven bone surrounded by osteoblasts?
Osteoma
Where do most Osteosarcomas arise in the body?
Metaphyseal region of long bones
What is the most common type of osteosarcoma based on its site of involvement?
Primary, solitary, intramedullary
Which radiographic finding is characteristic of osteosarcomas?
Triangular shadow (Codman triangle)
What is essential for diagnosing osteosarcomas?
Production of mineralized or unmineralized bone (osteoid)
What is a common histological feature of osteosarcomas?
Bizarre tumor giant cells
Which subtype of osteosarcoma occurs most commonly in older adults with Paget disease or previous radiation exposure?
Secondary osteosarcoma
Which of the following statements about chondrosarcoma is NOT true?
Chondrosarcomas frequently involve the distal extremities, unlike enchondromas.
Which of the following statements regarding the grading and metastatic potential of chondrosarcoma is correct?
Grade 3 chondrosarcomas have a 70% chance of hematogenous dissemination.
Which of the following statements regarding the treatment of chondrosarcoma is correct?
Conventional chondrosarcomas are treated with wide surgical excision, while chemotherapy is added for the mesenchymal and dedifferentiated variants.
Which of the following statements about fibrous cortical defects and nonossifying fibromas is correct?
Fibrous cortical defects are probably developmental abnormalities and are eccentrically located in the metaphysis of the distal femur or proximal tibia.
Which of the following statements regarding the location of chondrosarcomas is correct?
Chondrosarcomas frequently involve the axial skeleton, pelvis, and shoulder.
What is a defining characteristic of osteochondromas?
Having a bony stalk and a cartilaginous cap
Which condition is associated with multiple hereditary osteochondromas?
Maffucci syndrome
What differentiates chondromas from chondrosarcomas?
Being composed of hyaline cartilage
What is a common age range for the development of chondromas?
20 - 50 years old
Which genetic mutation is associated with syndromic types of chondromas?
Isocitrate dehydrogenase I (IDH1)
Test your knowledge on the classification of bone tumors including bone-forming tumors, cartilage-forming tumors, fibrous/fibroosseous tumors, and miscellaneous bone tumors. Learn about specific types of bone tumors such as osteoma, osteoid osteoma, and osteoblastoma.
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