Herpesviridae

• Herpesviridae are large double-stranded DNA viruses that replicate in the host cell nucleus.
• They have a linear genome coding for approximately 100 genes and can cause latent and lytic infections.
• There are three subfamilies of herpesviruses: alpha, beta, and gamma.
• Gamma herpesviruses establish latent infection in lymphocytes.
• There are six types of human herpesviruses: HHV-1, HHV-2, HHV-3, HHV-4, HHV-5, and HHV-8.
• HSV-1 and HSV-2 are alphaherpesviruses that cause oral and/or genital herpes.
• VZV is an alphaherpesvirus that causes chickenpox and shingles.
• EBV is a gammaherpesvirus that causes infectious mononucleosis and other diseases.
• HSV subverts host immune responses, including blocking IFN-induced inhibition of viral protein synthesis and reducing humoral immune response.
• Man is the only natural host for HSV.

Test your knowledge of Herpesviridae with our quiz! From the different subfamilies to the types of human herpesviruses, this quiz will challenge your understanding of these double-stranded DNA viruses. See if you can identify which herpesviruses cause specific diseases, and learn more about how these viruses interact with host immune responses. Don't miss out on the chance to expand your knowledge of Herpesviridae!