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Questions and Answers
Which of the following is NOT a subfamily of herpesviruses?
Which of the following is NOT a subfamily of herpesviruses?
- Delta (correct)
- Gamma
- Beta
- Alpha
Which herpesvirus causes chickenpox and shingles?
Which herpesvirus causes chickenpox and shingles?
- HHV-2
- HHV-4
- HHV-3 (correct)
- HHV-1
Which herpesvirus causes infectious mononucleosis?
Which herpesvirus causes infectious mononucleosis?
- HHV-2
- HHV-4 (correct)
- HHV-1
- HHV-3
Which herpesvirus subverts host immune responses?
Which herpesvirus subverts host immune responses?
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Which statement about herpesviruses is true?
Which statement about herpesviruses is true?
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Study Notes
- Herpesviridae are large double-stranded DNA viruses that replicate in the host cell nucleus.
- They have a linear genome coding for approximately 100 genes and can cause latent and lytic infections.
- There are three subfamilies of herpesviruses: alpha, beta, and gamma.
- Gamma herpesviruses establish latent infection in lymphocytes.
- There are six types of human herpesviruses: HHV-1, HHV-2, HHV-3, HHV-4, HHV-5, and HHV-8.
- HSV-1 and HSV-2 are alphaherpesviruses that cause oral and/or genital herpes.
- VZV is an alphaherpesvirus that causes chickenpox and shingles.
- EBV is a gammaherpesvirus that causes infectious mononucleosis and other diseases.
- HSV subverts host immune responses, including blocking IFN-induced inhibition of viral protein synthesis and reducing humoral immune response.
- Man is the only natural host for HSV.
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