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Questions and Answers
Which virus is associated with mononucleosis?
Which virus is associated with mononucleosis?
- Epstein-Barr virus (correct)
- Herpes simplex type two
- Varicella zoster virus
- Cytomegalovirus
Which herpes virus is linked to a condition called hairy leukoplakia?
Which herpes virus is linked to a condition called hairy leukoplakia?
- HHV-8
- Herpes simplex type one
- HHV-6 (correct)
- Varicella zoster virus
Which virus tends to come out in immune-compromised patients?
Which virus tends to come out in immune-compromised patients?
- Cytomegalovirus (correct)
- Herpes simplex type two
- HHV-8
- Varicella zoster virus
Which herpes virus is associated with a malignant tumor in HIV-positive patients?
Which herpes virus is associated with a malignant tumor in HIV-positive patients?
Which virus is often asymptomatic in over half of the population it has been exposed to?
Which virus is often asymptomatic in over half of the population it has been exposed to?
Which herpes virus is responsible for chickenpox?
Which herpes virus is responsible for chickenpox?
What is the primary mode of transmission for herpes lesions?
What is the primary mode of transmission for herpes lesions?
Before the practice of wearing gloves, which group was at risk of herpetic whitlow?
Before the practice of wearing gloves, which group was at risk of herpetic whitlow?
What is 'scrum pox' and how can it be acquired?
What is 'scrum pox' and how can it be acquired?
What is the key spot for diagnosis if a biopsy is indicated for classic herpes lesions?
What is the key spot for diagnosis if a biopsy is indicated for classic herpes lesions?
What is the characteristic feature observed within a couple of days of ulcer onset in virally modified cells?
What is the characteristic feature observed within a couple of days of ulcer onset in virally modified cells?
In which individuals can secondary manifestation of herpes occur?
In which individuals can secondary manifestation of herpes occur?
What is the recommended treatment for primary infection with herpes simplex virus?
What is the recommended treatment for primary infection with herpes simplex virus?
How does recurrent herpes labialis typically present?
How does recurrent herpes labialis typically present?
What can recurrent herpes lead to through autoinoculation?
What can recurrent herpes lead to through autoinoculation?
How can primary herpes infection be differentiated from other ulcers?
How can primary herpes infection be differentiated from other ulcers?
How are recurrent herpes lesions typically presented in immunocompetent patients?
How are recurrent herpes lesions typically presented in immunocompetent patients?
What is the significance of good hygiene practices in managing recurrent herpes?
What is the significance of good hygiene practices in managing recurrent herpes?
What are the symptoms of chickenpox?
What are the symptoms of chickenpox?
How is the chickenpox virus, varicella, primarily spread?
How is the chickenpox virus, varicella, primarily spread?
What can varicella, the chickenpox virus, cause in patients, in addition to skin involvement?
What can varicella, the chickenpox virus, cause in patients, in addition to skin involvement?
What is a characteristic of shingles, or herpes zoster?
What is a characteristic of shingles, or herpes zoster?
Who is at a higher risk of developing shingles?
Who is at a higher risk of developing shingles?
What conditions can Epstein-Barr virus (EBV) lead to?
What conditions can Epstein-Barr virus (EBV) lead to?
What triggers reactivation of the herpes simplex virus?
What triggers reactivation of the herpes simplex virus?
Which type of herpes simplex virus tends to infect below the waist?
Which type of herpes simplex virus tends to infect below the waist?
What are the symptoms of initial exposure to the herpes simplex virus?
What are the symptoms of initial exposure to the herpes simplex virus?
What is responsible for oral and labial disease?
What is responsible for oral and labial disease?
Where can primary exposure to the virus result in ulcers in the mouth?
Where can primary exposure to the virus result in ulcers in the mouth?
What is distinct from recurrent herpes and requires different intervention?
What is distinct from recurrent herpes and requires different intervention?
Study Notes
Overview of Herpes Simplex Virus
- Herpes simplex virus is a DNA virus that thrives in epithelial cells and nerve ganglia.
- Initial exposure to the virus can cause symptoms such as malaise, anorexia, low-grade fever, and oral ulcerative lesions.
- The virus remains in the body and can reactivate, often presenting as recurrent herpes labialis on the lips or intraoral forms.
- HSV-1 tends to infect above the waist, while HSV-2 infects below the waist, but their clinical and histopathological characteristics are similar.
- HSV-1 is commonly contracted through routine household contact and is responsible for oral and labial disease.
- Subclinical infections can occur, leading to transmission of the virus without obvious lesions.
- Reactivation triggers for the virus can include hormonal changes, illness, emotional factors, oral pathology, immune senescence, trauma, and UV exposure.
- Half of those infected experience reactivation, often referred to as fever blisters, and UV exposure is an unequivocal trigger for reactivation.
- Primary herpetic gingivostomatitis is distinct from recurrent herpes and requires different intervention.
- Primary exposure to the virus can result in ulcers anywhere in the mouth, including keratinized and non-keratinized mucosa.
- Keratinized mucosa includes the top of the tongue, dorsal tongue, and attached gingiva, while non-keratinized mucosa is found in most other areas of the mouth.
- Distinguishing between primary and recurrent herpes is important for appropriate intervention.
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Test your knowledge of Herpes Simplex Virus (HSV) with this quiz. Explore the characteristics, symptoms, transmission, and reactivation triggers of HSV-1 and HSV-
