Hereditary Spherocytosis and Elliptocytosis Quiz
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Questions and Answers

What is the primary defect that causes hereditary spherocytosis?

  • A deficiency in erythrocytes' ability to adapt to changes in their environment
  • A deficiency in band 4.1 proteins
  • A deficiency in hemoglobin production
  • A deficiency in spectrin gene expression (correct)

    • What is the primary defect that causes hereditary elliptocytosis?

  • A deficiency in erythrocytes' ability to adapt to changes in their environment
  • A deficiency in spectrin gene expression
  • A deficiency in hemoglobin production
  • A deficiency in band 4.1 proteins (correct)

    • What is the result of erythrocytes' inability to adapt to changes in their environment in both hereditary spherocytosis and hereditary elliptocytosis?

  • Increased hemoglobin production
  • Premature destruction of the cell (correct)
  • Mechanical deformation of erythrocytes
  • Decreased osmotic pressure

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