30 Questions
What is the primary mechanism by which the hepatitis C virus causes cell necrosis?
Immune-mediated cytolysis
Which of the following groups is at increased risk of acquiring hepatitis C?
People with HIV
What is the correct sequence of tests for diagnosing hepatitis C?
EIA → RIBA → PCR
What is a common mode of transmission of hepatitis C?
Sharing of needles and syringes
What is a characteristic of the hepatitis C virus?
It is a non-cytopathic virus
Which of the following professions is at increased risk of acquiring hepatitis C?
Healthcare and emergency medical personnel
What is a rare case of Hepatitis D transmission?
Mother to child at birth
What is the purpose of using Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) in Hepatitis D diagnosis?
To monitor ongoing HDV infection
What is the primary method of preventing Hepatitis D virus?
Prevention of Hepatitis B virus
What is the most common outcome of acute HDV and HBV infection?
Chronic hepatitis in 80% of cases
Which of the following is a high-risk population for Hepatitis D superinfection?
Chronic HBV carriers
What is the treatment for Hepatitis D virus?
There is no specific treatment for HDV
What is the primary route of transmission for Hepatitis A?
Contaminated food and water
What is the characteristic shape of the Hepatitis A virus?
Cubic symmetry
Which of the following is a common symptom of Hepatitis A infection in adults?
Yellowing of the skin and sclera
What is the purpose of PCR and ELISA assays in laboratory diagnosis of Hepatitis A?
To detect the presence of antibodies in the bloodstream
Which population is at an increased risk of Hepatitis A infection due to occupational exposure?
Food handlers
What is the significance of detecting HAV in stool samples during laboratory diagnosis?
It is usually detected 1-2 weeks before the onset of jaundice
What is the primary reason for testing donated blood for HCV?
To prevent transmission of HCV through blood transfusions
What is the average period from exposure to symptom onset in people with newly acquired HCV infection?
2-12 weeks
Which of the following is a component of the treatment for chronic HCV infection?
PEGylated interferon combined with ribavirin
What is the purpose of the Recombinant Immunoblot Assay (RIBA) in the diagnosis of HCV?
To confirm the presence of HCV antibodies in the blood
What is a common extrahepatic manifestation of chronic HCV infection?
Diabetes
What is a recommended precaution for people living with Hepatitis C?
All of the above
What is the primary mode of prevention for Hepatitis B?
Getting vaccinated
Which of the following is a characteristic of the Hepatitis B virus?
Single-stranded RNA genome surrounded by an icosahedral capsid
What is the diagnostic significance of Hepatitis B envelope antigen (HBeAg) in the serum?
Indicates infectivity of the individual
Which of the following populations is at high risk for Hepatitis B infection?
All of the above
What is the laboratory diagnosis for chronic Hepatitis B infection?
HBsAg (+) and anti-HBc (+) with IgG only
What is the classification of the Hepatitis C virus?
Genus: Hepacivirus, Family: Flaviviridae
This quiz covers the characteristics of a non-cytopathic virus that affects the liver, its transmission routes, and diagnostic tests. Learn about the mechanisms of cell necrosis, natural hosts, and more.
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