Podcast
Questions and Answers
Which type of viruses are generally more genetically stable than RNA viruses?
Which type of viruses are generally more genetically stable than RNA viruses?
- Paramyxoviruses
- Retroviruses
- DNA viruses (correct)
- RNA viruses
What is the term used to describe the presence of genetically different viral variants in the same infected individual?
What is the term used to describe the presence of genetically different viral variants in the same infected individual?
- Quasi-species (correct)
- Re-assortment
- Selective advantage
- Genetic drift
Which viral replicative enzyme is the most error-prone?
Which viral replicative enzyme is the most error-prone?
- DNA polymerase of DNA viruses
- DNA polymerase of retroviruses
- RNA polymerase of paramyxoviruses
- Reverse transcriptase of HBV and retroviruses (correct)
Which enzyme in HCV replication contributes to the high degree of variability in the virus?
Which enzyme in HCV replication contributes to the high degree of variability in the virus?
Which HCV genotype is the most prevalent worldwide and in Europe?
Which HCV genotype is the most prevalent worldwide and in Europe?
What is the most important baseline predictor for response to Peg-IFN + Ribavirin Combination Therapy for HCV?
What is the most important baseline predictor for response to Peg-IFN + Ribavirin Combination Therapy for HCV?
What is the most prone to variation among HIV genome regions?
What is the most prone to variation among HIV genome regions?
Which virus has the smallest genome of known animal DNA viruses?
Which virus has the smallest genome of known animal DNA viruses?
What is the mutation rate of Reverse Transcriptase in HBV genome?
What is the mutation rate of Reverse Transcriptase in HBV genome?
Which type of inhibitors target the fusion process of the virus?
Which type of inhibitors target the fusion process of the virus?
What is the pattern of lamivudine resistance mutations that strongly reduces the binding affinity with neutralizing antibodies?
What is the pattern of lamivudine resistance mutations that strongly reduces the binding affinity with neutralizing antibodies?
Which viruses are subject to antigenic drift?
Which viruses are subject to antigenic drift?
What is antigenic shift?
What is antigenic shift?
Which virus is prone to antigenic shift and why?
Which virus is prone to antigenic shift and why?
What is viral recombination?
What is viral recombination?
Which virus is known for having a highly error-prone replicative enzyme?
Which virus is known for having a highly error-prone replicative enzyme?
What is the term used to describe the presence of a swarm of genetically different viral variants in the same infected individual?
What is the term used to describe the presence of a swarm of genetically different viral variants in the same infected individual?
Which type of viruses are generally more genetically stable than RNA viruses?
Which type of viruses are generally more genetically stable than RNA viruses?
Which enzyme in HIV replication is responsible for the high mutation rate of the virus?
Which enzyme in HIV replication is responsible for the high mutation rate of the virus?
Which HCV genotype is significantly more prevalent among patients with liver cirrhosis and those with decompensated liver disease requiring liver transplantation?
Which HCV genotype is significantly more prevalent among patients with liver cirrhosis and those with decompensated liver disease requiring liver transplantation?
What is the Immediate Precursor of HIV-1?
What is the Immediate Precursor of HIV-1?
What is the estimated percentage of HIV isolates that represent recombinants between different subtypes?
What is the estimated percentage of HIV isolates that represent recombinants between different subtypes?
Which type of inhibitors target the attachment process of the virus?
Which type of inhibitors target the attachment process of the virus?
What is the most common mutation pattern associated with lamivudine resistance in HBV?
What is the most common mutation pattern associated with lamivudine resistance in HBV?
Which virus has a replication strategy that is unique among all DNA viruses?
Which virus has a replication strategy that is unique among all DNA viruses?
What is the term used to describe the ability of viruses to change their genetic makeup over time?
What is the term used to describe the ability of viruses to change their genetic makeup over time?
Which viruses are subject to antigenic drift?
Which viruses are subject to antigenic drift?
Which virus is prone to antigenic shift due to the segmented nature of its genome?
Which virus is prone to antigenic shift due to the segmented nature of its genome?
What is the phenomenon that occurs during replication of RNA viruses, when the viral enzyme can jump from one template strand to another, dragging the chain of newly synthesized one and with the generation of a hybrid polynucleotide strand?
What is the phenomenon that occurs during replication of RNA viruses, when the viral enzyme can jump from one template strand to another, dragging the chain of newly synthesized one and with the generation of a hybrid polynucleotide strand?
What is the term used to describe the exchange of homologous stretches of genetic material between two virus strains co-infecting the same cell, with the generation of a viral progeny presenting stable phenotypic characteristics of both parent viruses?
What is the term used to describe the exchange of homologous stretches of genetic material between two virus strains co-infecting the same cell, with the generation of a viral progeny presenting stable phenotypic characteristics of both parent viruses?
