Podcast
Questions and Answers
What enzyme converts phospholipids from the platelet membrane into arachidonic acid?
What enzyme converts phospholipids from the platelet membrane into arachidonic acid?
- Platelet aggregation enzyme
- Cyclooxygenase
- Phospholipase A2 (correct)
- Prostaglandin G2
- Thromboxane synthetase
Which enzyme converts prostaglandins into thromboxane A2?
Which enzyme converts prostaglandins into thromboxane A2?
- Prostaglandin G2
- Phospholipase A2
- Cyclooxygenase
- Arachidonic acid converter
- Thromboxane synthetase (correct)
What is the role of Ca21 in promoting platelet aggregation and vasoconstriction?
What is the role of Ca21 in promoting platelet aggregation and vasoconstriction?
- Inhibiting enzyme activity
- Converting arachidonic acid
- Released from the dense tubules (correct)
- Preventing platelet aggregation
- Activating phospholipase A2
How does aspirin function to decrease platelet activity?
How does aspirin function to decrease platelet activity?
Which factor initiates the intrinsic pathway of coagulation?
Which factor initiates the intrinsic pathway of coagulation?
Which negative-charged surface activates the contact factor group in the coagulation system?
Which negative-charged surface activates the contact factor group in the coagulation system?
What is the main role of ionized calcium in the coagulation process?
What is the main role of ionized calcium in the coagulation process?
Which of the following is NOT a synonym for factor VII?
Which of the following is NOT a synonym for factor VII?
What is the effect of vitamin K on the coagulation factors with glutamic acid in their N-terminal?
What is the effect of vitamin K on the coagulation factors with glutamic acid in their N-terminal?
What is the main function of the vitamin K-dependent coagulation factors?
What is the main function of the vitamin K-dependent coagulation factors?
Which coagulation factor is also known as the 'Christmas factor'?
Which coagulation factor is also known as the 'Christmas factor'?
How does the increase in levels of fibrinogen, prothrombin, and factor VIII relate to the coagulation process?
How does the increase in levels of fibrinogen, prothrombin, and factor VIII relate to the coagulation process?
Which serpin family member is a vitamin K-dependent plasma glycoprotein that increases the ability of ZPI to inhibit factor Xa 2000-fold?
Which serpin family member is a vitamin K-dependent plasma glycoprotein that increases the ability of ZPI to inhibit factor Xa 2000-fold?
Which inhibitor is a nonspecific, heparin-binding serpin that can act as both an anticoagulant and a procoagulant depending on its target?
Which inhibitor is a nonspecific, heparin-binding serpin that can act as both an anticoagulant and a procoagulant depending on its target?
Which member of the serpin family can inhibit factor XIa in a separate reaction that does not require protein Z, phospholipid, and Ca21?
Which member of the serpin family can inhibit factor XIa in a separate reaction that does not require protein Z, phospholipid, and Ca21?
What accelerates the inhibition of factor XIa by ZPI?
What accelerates the inhibition of factor XIa by ZPI?
Which serpin family member is a potent inhibitor of factor Xa when in a complex with Ca21 and phospholipid?
Which serpin family member is a potent inhibitor of factor Xa when in a complex with Ca21 and phospholipid?
Which serpin family member is capable of digesting plasma fibrinogen, factor V, factor VIII, and fibronectin when free in circulation?
Which serpin family member is capable of digesting plasma fibrinogen, factor V, factor VIII, and fibronectin when free in circulation?
What is the primary function of heparan sulfate in the text?
What is the primary function of heparan sulfate in the text?
How does the pharmaceutical anticoagulant heparin resemble endothelial cell (EC) heparan sulfate?
How does the pharmaceutical anticoagulant heparin resemble endothelial cell (EC) heparan sulfate?
What is the initial response of the vascular system to injury according to the text?
What is the initial response of the vascular system to injury according to the text?
What is the function of ADAMTS13 secreted from endothelial cells (ECs)?
What is the function of ADAMTS13 secreted from endothelial cells (ECs)?
What is the role of von Willebrand factor (VWF) when the vascular system is damaged?
What is the role of von Willebrand factor (VWF) when the vascular system is damaged?
What is the purpose of the exposed collagen-rich basement membrane/subendothelial connective tissue when the vascular system is damaged?
What is the purpose of the exposed collagen-rich basement membrane/subendothelial connective tissue when the vascular system is damaged?
What is the primary role of the activated protein C-protein S complex?
What is the primary role of the activated protein C-protein S complex?
What is the approximate percentage of protein S that is free in the plasma?
What is the approximate percentage of protein S that is free in the plasma?
What is the significance of protein S-C4bBP binding in inflammatory conditions?
What is the significance of protein S-C4bBP binding in inflammatory conditions?
What is the condition called when neonates completely lack protein C?
What is the condition called when neonates completely lack protein C?
What is the primary function of the protein C regulatory system?
What is the primary function of the protein C regulatory system?
What is the primary consequence of chronic acquired or inherited deficiency or mutations in the protein C or protein S pathways?
What is the primary consequence of chronic acquired or inherited deficiency or mutations in the protein C or protein S pathways?
