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Questions and Answers
What is the main function of hemostasis?
What is the main function of hemostasis?
- Prevention of blood clotting
- Formation of blood clot
- Prevention of blood loss (correct)
- Formation of platelet plug
Which is NOT a mechanism for achieving hemostasis?
Which is NOT a mechanism for achieving hemostasis?
- Blood clot removal (correct)
- Growth of fibrous tissue into the blood clot
- Vascular constriction
- Formation of a platelet plug
What is the normal concentration of platelets in the blood?
What is the normal concentration of platelets in the blood?
- 50,000 - 100,000 per microliter
- 500,000 - 700,000 per microliter
- 150,000 - 300,000 per microliter (correct)
- 300,000 - 500,000 per microliter
What happens to platelets when they come in contact with a damaged vascular surface?
What happens to platelets when they come in contact with a damaged vascular surface?
What is the life span of platelets in the blood?
What is the life span of platelets in the blood?
What is the first mechanism for achieving hemostasis?
What is the first mechanism for achieving hemostasis?
What are platelets also called?
What are platelets also called?
What structures form on the surfaces of platelets when they come in contact with damaged vascular surfaces?
What structures form on the surfaces of platelets when they come in contact with damaged vascular surfaces?
What initiates the clotting process in the blood vessel?
What initiates the clotting process in the blood vessel?
Which test is used to evaluate capillary resistance by counting the number of petechial hemorrhages?
Which test is used to evaluate capillary resistance by counting the number of petechial hemorrhages?
What does the Duke's method of bleeding time test involve?
What does the Duke's method of bleeding time test involve?
What is the normal range for bleeding time as per Ivy's method?
What is the normal range for bleeding time as per Ivy's method?
Which condition causes excessive bleeding in humans due to platelet deficiency?
Which condition causes excessive bleeding in humans due to platelet deficiency?
What is responsible for cleaning up extra and old clots by breaking them down?
What is responsible for cleaning up extra and old clots by breaking them down?
What type of abnormal clot freely travels through the bloodstream?
What type of abnormal clot freely travels through the bloodstream?
"What is activated by tissue plasminogen activator (t-PA) to break down unnecessary blood clots?"
"What is activated by tissue plasminogen activator (t-PA) to break down unnecessary blood clots?"
"What is the function of the cuff of the sphygmomanometer in Duke's method of Bleeding Time test?"
"What is the function of the cuff of the sphygmomanometer in Duke's method of Bleeding Time test?"
"What does an abnormal clot that develops in a blood vessel occlude?"
"What does an abnormal clot that develops in a blood vessel occlude?"
"What does an emboli refer to?"
"What does an emboli refer to?"
Platelets are formed in the liver from megakaryocytes.
Platelets are formed in the liver from megakaryocytes.
Vascular constriction is not a mechanism for achieving hemostasis.
Vascular constriction is not a mechanism for achieving hemostasis.
The normal concentration of platelets in the blood is less than 100,000 per microliter.
The normal concentration of platelets in the blood is less than 100,000 per microliter.
Platelets have a life span of 12 to 16 days.
Platelets have a life span of 12 to 16 days.
Platelets have a nucleus.
Platelets have a nucleus.
The formation of a platelet plug involves platelets adhering to smooth vessel walls.
The formation of a platelet plug involves platelets adhering to smooth vessel walls.
Vascular constriction results from factors released from undamaged tissue.
Vascular constriction results from factors released from undamaged tissue.
Platelets undergo phagocytosis in the spleen after 12 to 15 days.
Platelets undergo phagocytosis in the spleen after 12 to 15 days.
The growth of fibrous tissue into the blood clot occurs to dissolve the clot and prevent further damage to the vessel.
The growth of fibrous tissue into the blood clot occurs to dissolve the clot and prevent further damage to the vessel.
Platelets do not change their characteristics upon contact with a damaged vascular surface.
Platelets do not change their characteristics upon contact with a damaged vascular surface.
The formation of a blood clot is not a mechanism for achieving hemostasis.
The formation of a blood clot is not a mechanism for achieving hemostasis.
Hemostasis does not involve the eventual growth of fibrous tissue into the blood clot.
Hemostasis does not involve the eventual growth of fibrous tissue into the blood clot.
The injured tissues and vascular endothelium release tissue plasminogen activator (t-PA) immediately after the clot has stopped the bleeding.
The injured tissues and vascular endothelium release tissue plasminogen activator (t-PA) immediately after the clot has stopped the bleeding.
The Hess test involves applying the cuff of the sphygmomanometer above a marked circle and maintaining pressure for five minutes.
The Hess test involves applying the cuff of the sphygmomanometer above a marked circle and maintaining pressure for five minutes.
The Duke's method of bleeding time test involves wrapping the cuff of the sphygmomanometer around the upper arm and inflating it to a pressure of 50 mmHg.
The Duke's method of bleeding time test involves wrapping the cuff of the sphygmomanometer around the upper arm and inflating it to a pressure of 50 mmHg.
The normal range for bleeding time as per Ivy's method is 2 – 6 minutes.
The normal range for bleeding time as per Ivy's method is 2 – 6 minutes.
The Clotting time (CT) is the time taken for the blood to clot inside the vascular system.
The Clotting time (CT) is the time taken for the blood to clot inside the vascular system.
Vitamin K deficiency, hemophilia, and thrombocytopenia are conditions that cause excessive bleeding in humans due to platelet deficiency.
Vitamin K deficiency, hemophilia, and thrombocytopenia are conditions that cause excessive bleeding in humans due to platelet deficiency.
An abnormal clot that develops in a blood vessel is called an emboli.
An abnormal clot that develops in a blood vessel is called an emboli.
The Hess test determines capillary resistance by counting the number of spots formed on a filter paper after puncturing the thumb.
The Hess test determines capillary resistance by counting the number of spots formed on a filter paper after puncturing the thumb.
Platelets are also called thrombocytes.
Platelets are also called thrombocytes.
Thromboembolic conditions involve a freely circulating clot called a thrombus.
Thromboembolic conditions involve a freely circulating clot called a thrombus.
The Duke's method of bleeding time test provides information about the function of platelets and the capillary wall.
The Duke's method of bleeding time test provides information about the function of platelets and the capillary wall.
Thromboembolic conditions prevent blood from flowing normally by occluding small blood vessels.
Thromboembolic conditions prevent blood from flowing normally by occluding small blood vessels.
Study Notes
Hemostasis
- The main function of hemostasis is to prevent excessive bleeding when a blood vessel is injured.
- Hemostasis involves three main mechanisms: vascular constriction, platelet plug formation, and blood coagulation.
Platelet Function
- Platelets, also called thrombocytes, are formed in the bone marrow from megakaryocytes.
- The normal concentration of platelets in the blood is 150,000-450,000 per microliter.
- Platelets have a life span of 12 to 16 days.
- When platelets come into contact with a damaged vascular surface, they undergo a change in their characteristics, leading to the formation of pseudopodia and release of granules.
Platelet Plug Formation
- Platelet plug formation is the first mechanism for achieving hemostasis.
- When platelets come into contact with a damaged vascular surface, they adhere to the surface, forming a platelet plug.
- On the surface of platelets, pseudopodia form and granules are released, leading to platelet activation.
Blood Clotting
- The formation of a blood clot is the second mechanism for achieving hemostasis.
- The clotting process is initiated by the release of tissue plasminogen activator (t-PA) from injured tissues and vascular endothelium.
- t-PA activates plasminogen, which breaks down fibrin clots.
Bleeding Time Test
- The bleeding time test is used to evaluate platelet function and capillary resistance.
- Duke's method of bleeding time test involves inflating a cuff on the upper arm to a pressure of 40 mmHg and making a small puncture wound to measure the time it takes for bleeding to stop.
- The normal range for bleeding time as per Ivy's method is 2-6 minutes.
Clotting Disorders
- Thrombocytopenia is a condition that causes excessive bleeding due to platelet deficiency.
- Thromboembolic conditions involve the formation of abnormal clots that can occlude small blood vessels.
- Plasmin activators, such as t-PA, break down unnecessary blood clots.
Other
- The Hess test, also known as the tourniquet test, is used to evaluate capillary resistance.
- An emboli refers to an abnormal clot that breaks loose and travels through the bloodstream.
- Fibrous tissue growth into the blood clot helps to dissolve the clot and prevent further damage to the vessel.
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Description
Test your knowledge of the mechanisms involved in hemostasis, the process of preventing blood loss when a blood vessel is damaged. This quiz covers topics such as vascular constriction, platelet plug formation, blood clotting, and fibrous tissue growth.
