Hemostasis Mechanisms Quiz
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Questions and Answers

What is the main function of hemostasis?

  • Prevention of blood clotting
  • Formation of blood clot
  • Prevention of blood loss (correct)
  • Formation of platelet plug
  • Which is NOT a mechanism for achieving hemostasis?

  • Blood clot removal (correct)
  • Growth of fibrous tissue into the blood clot
  • Vascular constriction
  • Formation of a platelet plug
  • What is the normal concentration of platelets in the blood?

  • 50,000 - 100,000 per microliter
  • 500,000 - 700,000 per microliter
  • 150,000 - 300,000 per microliter (correct)
  • 300,000 - 500,000 per microliter
  • What happens to platelets when they come in contact with a damaged vascular surface?

    <p>They adhere to the vessel wall and each other, forming a plug</p> Signup and view all the answers

    What is the life span of platelets in the blood?

    <p>8 to 12 days</p> Signup and view all the answers

    What is the first mechanism for achieving hemostasis?

    <p>Vascular constriction</p> Signup and view all the answers

    What are platelets also called?

    <p>Thrombocytes</p> Signup and view all the answers

    What structures form on the surfaces of platelets when they come in contact with damaged vascular surfaces?

    <p>'Pseudopods' and 'sticky' surfaces</p> Signup and view all the answers

    What initiates the clotting process in the blood vessel?

    <p>Damaged tissue and platelets</p> Signup and view all the answers

    Which test is used to evaluate capillary resistance by counting the number of petechial hemorrhages?

    <p>Hess test</p> Signup and view all the answers

    What does the Duke's method of bleeding time test involve?

    <p>Puncturing the thumb and touching the bleeding site with a filter paper every 30 seconds</p> Signup and view all the answers

    What is the normal range for bleeding time as per Ivy's method?

    <p>2 - 8 minutes</p> Signup and view all the answers

    Which condition causes excessive bleeding in humans due to platelet deficiency?

    <p>Thrombocytopenia</p> Signup and view all the answers

    What is responsible for cleaning up extra and old clots by breaking them down?

    <p>Fibrinolysis</p> Signup and view all the answers

    What type of abnormal clot freely travels through the bloodstream?

    <p>Embolus</p> Signup and view all the answers

    "What is activated by tissue plasminogen activator (t-PA) to break down unnecessary blood clots?"

    <p>Plasminogen</p> Signup and view all the answers

    "What is the function of the cuff of the sphygmomanometer in Duke's method of Bleeding Time test?"

    <p>To maintain pressure at 40 mmHg</p> Signup and view all the answers

    "What does an abnormal clot that develops in a blood vessel occlude?"

    <p>Small blood vessels only</p> Signup and view all the answers

    "What does an emboli refer to?"

    <p>A clot that freely circulates through the bloodstream</p> Signup and view all the answers

    Platelets are formed in the liver from megakaryocytes.

    <p>False</p> Signup and view all the answers

    Vascular constriction is not a mechanism for achieving hemostasis.

    <p>False</p> Signup and view all the answers

    The normal concentration of platelets in the blood is less than 100,000 per microliter.

    <p>False</p> Signup and view all the answers

    Platelets have a life span of 12 to 16 days.

    <p>False</p> Signup and view all the answers

    Platelets have a nucleus.

    <p>False</p> Signup and view all the answers

    The formation of a platelet plug involves platelets adhering to smooth vessel walls.

    <p>False</p> Signup and view all the answers

    Vascular constriction results from factors released from undamaged tissue.

    <p>False</p> Signup and view all the answers

    Platelets undergo phagocytosis in the spleen after 12 to 15 days.

    <p>False</p> Signup and view all the answers

    The growth of fibrous tissue into the blood clot occurs to dissolve the clot and prevent further damage to the vessel.

    <p>False</p> Signup and view all the answers

    Platelets do not change their characteristics upon contact with a damaged vascular surface.

    <p>False</p> Signup and view all the answers

    The formation of a blood clot is not a mechanism for achieving hemostasis.

    <p>False</p> Signup and view all the answers

    Hemostasis does not involve the eventual growth of fibrous tissue into the blood clot.

    <p>False</p> Signup and view all the answers

    The injured tissues and vascular endothelium release tissue plasminogen activator (t-PA) immediately after the clot has stopped the bleeding.

    <p>False</p> Signup and view all the answers

    The Hess test involves applying the cuff of the sphygmomanometer above a marked circle and maintaining pressure for five minutes.

    <p>True</p> Signup and view all the answers

    The Duke's method of bleeding time test involves wrapping the cuff of the sphygmomanometer around the upper arm and inflating it to a pressure of 50 mmHg.

    <p>False</p> Signup and view all the answers

    The normal range for bleeding time as per Ivy's method is 2 – 6 minutes.

    <p>False</p> Signup and view all the answers

    The Clotting time (CT) is the time taken for the blood to clot inside the vascular system.

    <p>False</p> Signup and view all the answers

    Vitamin K deficiency, hemophilia, and thrombocytopenia are conditions that cause excessive bleeding in humans due to platelet deficiency.

    <p>False</p> Signup and view all the answers

    An abnormal clot that develops in a blood vessel is called an emboli.

    <p>False</p> Signup and view all the answers

    The Hess test determines capillary resistance by counting the number of spots formed on a filter paper after puncturing the thumb.

    <p>True</p> Signup and view all the answers

    Platelets are also called thrombocytes.

    <p>True</p> Signup and view all the answers

    Thromboembolic conditions involve a freely circulating clot called a thrombus.

    <p>False</p> Signup and view all the answers

    The Duke's method of bleeding time test provides information about the function of platelets and the capillary wall.

    <p>True</p> Signup and view all the answers

    Thromboembolic conditions prevent blood from flowing normally by occluding small blood vessels.

    <p>True</p> Signup and view all the answers

    Study Notes

    Hemostasis

    • The main function of hemostasis is to prevent excessive bleeding when a blood vessel is injured.
    • Hemostasis involves three main mechanisms: vascular constriction, platelet plug formation, and blood coagulation.

    Platelet Function

    • Platelets, also called thrombocytes, are formed in the bone marrow from megakaryocytes.
    • The normal concentration of platelets in the blood is 150,000-450,000 per microliter.
    • Platelets have a life span of 12 to 16 days.
    • When platelets come into contact with a damaged vascular surface, they undergo a change in their characteristics, leading to the formation of pseudopodia and release of granules.

    Platelet Plug Formation

    • Platelet plug formation is the first mechanism for achieving hemostasis.
    • When platelets come into contact with a damaged vascular surface, they adhere to the surface, forming a platelet plug.
    • On the surface of platelets, pseudopodia form and granules are released, leading to platelet activation.

    Blood Clotting

    • The formation of a blood clot is the second mechanism for achieving hemostasis.
    • The clotting process is initiated by the release of tissue plasminogen activator (t-PA) from injured tissues and vascular endothelium.
    • t-PA activates plasminogen, which breaks down fibrin clots.

    Bleeding Time Test

    • The bleeding time test is used to evaluate platelet function and capillary resistance.
    • Duke's method of bleeding time test involves inflating a cuff on the upper arm to a pressure of 40 mmHg and making a small puncture wound to measure the time it takes for bleeding to stop.
    • The normal range for bleeding time as per Ivy's method is 2-6 minutes.

    Clotting Disorders

    • Thrombocytopenia is a condition that causes excessive bleeding due to platelet deficiency.
    • Thromboembolic conditions involve the formation of abnormal clots that can occlude small blood vessels.
    • Plasmin activators, such as t-PA, break down unnecessary blood clots.

    Other

    • The Hess test, also known as the tourniquet test, is used to evaluate capillary resistance.
    • An emboli refers to an abnormal clot that breaks loose and travels through the bloodstream.
    • Fibrous tissue growth into the blood clot helps to dissolve the clot and prevent further damage to the vessel.

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    Description

    Test your knowledge of the mechanisms involved in hemostasis, the process of preventing blood loss when a blood vessel is damaged. This quiz covers topics such as vascular constriction, platelet plug formation, blood clotting, and fibrous tissue growth.

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