Hemostasis in Medical Physiology

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Hemostasis means prevention of ______ loss

blood

Platelets are also called ______

thrombocytes

Platelets are formed in the bone marrow from ______

megakaryocytes

The normal concentration of platelets in the blood is between 150,000 and 300,000 per ______

microliter Signup and view all the answers

Platelets don’t have ______

nucleus Signup and view all the answers

Platelets have a life span of 8 to 12 days, then removed by the tissue ______ system in spleen

macrophage Signup and view all the answers

When platelets come in contact with a damaged vascular surface, especially with ______ fibers, they immediately change their own characteristics

collagen Signup and view all the answers

Platelets adhere to collagen in the vessel wall and to each other forming the ______

plug Signup and view all the answers

Hemostasis is achieved by several mechanisms: 1. Vascular ______

constriction Signup and view all the answers

Formation of a blood clot as a result of blood ______

coagulation Signup and view all the answers

Vascular constriction results from local ______ spasm

myogenic Signup and view all the answers

Factors released from damaged tissue & platelets contribute to vascular ______

constriction Signup and view all the answers

If the cut in the blood vessel is very small, the cut is often sealed by a platelet plug, rather than by a blood ______

clot Signup and view all the answers

Blood coagulation and formation of blood ______ Factors from damaged tissue, platelets & from blood proteins initiate clotting process.

clot Signup and view all the answers

This process catalyzed by clotting factors & results in the formation of fibrin fibers running in all direction producing a ______ that entrap platelets & blood cells to form the clot.

meshwork Signup and view all the answers

This followed by formation of more fibrous tissue into the blood ______ to close the hole in the vessel permanently.

clot Signup and view all the answers

Fibrinolysis Extra clot and old clot cleaned up by factors that breakdown ______.

clot Signup and view all the answers

Activation of Plasminogen to Form Plasmin, Then Lysis of ______

Clots Signup and view all the answers

The injured tissues and vascular endothelium very slowly release a powerful activator called tissue plasminogen activator(t-PA) that a few days later, after the has stopped the bleeding, eventually converts plasminogen to plasmin, which in turn removes the remaining unnecessary blood .

clot Signup and view all the answers

Patients with bleeding disorders and tendencies require the following investigations: 1. Hess test (capillary resistance test). 2. Platelet count. 3. Bleeding time. 4. ______ time (whole blood coagulation time).

Clotting Signup and view all the answers

Hess test: ∙ With a pencil, mark a circle of 6 cm diameter in the antecubital fossa. ∙ Apply the cuff of the sphygmomanometer 1-2 inches above the circle and raise the pressure of the cuff to 50 mmHg and maintain the pressure for five minutes. ∙ Release the cuff and count the number of petichial hemorrhages (blue dots) on the circle. Counts of 0 – 8 are regarded as normal. ∙ If the test is positive (above 8 dots), this means that the capillary wall is abnormal and weakened by a disease. Bleeding time: is the time required to arrest bleeding from a ruptured ______.

capillary Signup and view all the answers

After cleaning the finger, do a puncture of about 4 mm deep in the thumb. Touch the bleeding site with a filter paper every 30 seconds. ∙ When bleeding is stopped count the number of spots formed on the paper and then divide it by two. ∙ This will give the bleeding time in ______.

minutes Signup and view all the answers

This method gives information about the function of the platelets and the ______ wall.

capillary Signup and view all the answers

This is the time taken for the blood to ______ out side the vascular system.

clot Signup and view all the answers

Hemostasis in Medical Physiology

Choose a study mode

Podcast

Questions and Answers

Hemostasis means prevention of ______ loss

Platelets are also called ______

Platelets are formed in the bone marrow from ______

The normal concentration of platelets in the blood is between 150,000 and 300,000 per ______

Platelets don’t have ______

Platelets have a life span of 8 to 12 days, then removed by the tissue ______ system in spleen

When platelets come in contact with a damaged vascular surface, especially with ______ fibers, they immediately change their own characteristics

Platelets adhere to collagen in the vessel wall and to each other forming the ______

Hemostasis is achieved by several mechanisms: 1. Vascular ______

Formation of a blood clot as a result of blood ______

Vascular constriction results from local ______ spasm

Factors released from damaged tissue & platelets contribute to vascular ______

If the cut in the blood vessel is very small, the cut is often sealed by a platelet plug, rather than by a blood ______

Blood coagulation and formation of blood ______ Factors from damaged tissue, platelets & from blood proteins initiate clotting process.

This process catalyzed by clotting factors & results in the formation of fibrin fibers running in all direction producing a ______ that entrap platelets & blood cells to form the clot.

This followed by formation of more fibrous tissue into the blood ______ to close the hole in the vessel permanently.

Fibrinolysis Extra clot and old clot cleaned up by factors that breakdown ______.

Activation of Plasminogen to Form Plasmin, Then Lysis of ______

The injured tissues and vascular endothelium very slowly release a powerful activator called tissue plasminogen activator(t-PA) that a few days later, after the has stopped the bleeding, eventually converts plasminogen to plasmin, which in turn removes the remaining unnecessary blood .

Patients with bleeding disorders and tendencies require the following investigations: 1. Hess test (capillary resistance test). 2. Platelet count. 3. Bleeding time. 4. ______ time (whole blood coagulation time).

After cleaning the finger, do a puncture of about 4 mm deep in the thumb. Touch the bleeding site with a filter paper every 30 seconds. ∙ When bleeding is stopped count the number of spots formed on the paper and then divide it by two. ∙ This will give the bleeding time in ______.

This method gives information about the function of the platelets and the ______ wall.

This is the time taken for the blood to ______ out side the vascular system.

More Like This

Hemostasis and Blood Clotting Mechanisms

Hemostasis Mechanisms Quiz

Module 1 - Blood Clotting

Coagulation Process in Hemostasis

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Hemostasis in Medical Physiology

Choose a study mode

Podcast

Questions and Answers

Hemostasis means prevention of ______ loss

Platelets are also called ______

Platelets are formed in the bone marrow from ______

The normal concentration of platelets in the blood is between 150,000 and 300,000 per ______

Platelets don’t have ______

Platelets have a life span of 8 to 12 days, then removed by the tissue ______ system in spleen

When platelets come in contact with a damaged vascular surface, especially with ______ fibers, they immediately change their own characteristics

Platelets adhere to collagen in the vessel wall and to each other forming the ______

Hemostasis is achieved by several mechanisms: 1. Vascular ______

Formation of a blood clot as a result of blood ______

Vascular constriction results from local ______ spasm

Factors released from damaged tissue & platelets contribute to vascular ______

If the cut in the blood vessel is very small, the cut is often sealed by a platelet plug, rather than by a blood ______

Blood coagulation and formation of blood ______ Factors from damaged tissue, platelets & from blood proteins initiate clotting process.

This process catalyzed by clotting factors & results in the formation of fibrin fibers running in all direction producing a ______ that entrap platelets & blood cells to form the clot.

This followed by formation of more fibrous tissue into the blood ______ to close the hole in the vessel permanently.

Fibrinolysis Extra clot and old clot cleaned up by factors that breakdown ______.

Activation of Plasminogen to Form Plasmin, Then Lysis of ______

The injured tissues and vascular endothelium very slowly release a powerful activator called tissue plasminogen activator(t-PA) that a few days later, after the ______ has stopped the bleeding, eventually converts plasminogen to plasmin, which in turn removes the remaining unnecessary blood ______.

Patients with bleeding disorders and tendencies require the following investigations: 1. Hess test (capillary resistance test). 2. Platelet count. 3. Bleeding time. 4. ______ time (whole blood coagulation time).

After cleaning the finger, do a puncture of about 4 mm deep in the thumb. Touch the bleeding site with a filter paper every 30 seconds. ∙ When bleeding is stopped count the number of spots formed on the paper and then divide it by two. ∙ This will give the bleeding time in ______.

This method gives information about the function of the platelets and the ______ wall.

This is the time taken for the blood to ______ out side the vascular system.

More Like This

Hemostasis and Blood Clotting Mechanisms

Hemostasis Mechanisms Quiz

Module 1 - Blood Clotting

Coagulation Process in Hemostasis

The injured tissues and vascular endothelium very slowly release a powerful activator called tissue plasminogen activator(t-PA) that a few days later, after the has stopped the bleeding, eventually converts plasminogen to plasmin, which in turn removes the remaining unnecessary blood .