Hemostasis Mechanisms Quiz

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What is the primary mechanism through which hemostasis is achieved when a blood vessel is severed?

Formation of a blood clot from blood coagulation

Growth of fibrous tissue into the blood clot

Formation of a platelet plug

Vascular constriction (correct)

Which factors contribute to the vascular constriction after a blood vessel has been cut or ruptured?

Local myogenic spasm

Autacoid factors from traumatized tissues and blood platelets

Nervous reflexes

All of the above (correct)

What is responsible for much of the vasoconstriction in smaller vessels?

Nervous reflexes initiated by pain nerve impulses

Autacoid factors from traumatized tissues and blood platelets

Local myogenic contraction of the blood vessels (correct)

Formation of a platelet plug

What causes the smooth muscle in the blood vessel wall to contract immediately after a vessel has been cut or ruptured?

Direct damage to the vascular wall Signup and view all the answers

What are the main outcomes of hemostasis when a vessel is severed or ruptured?

Formation of a blood clot as a result of blood coagulation and growth of fibrous tissue into the blood clot Signup and view all the answers

What causes even more vasoconstriction in smaller vessels after they have been cut or ruptured?

Local myogenic contraction of the blood vessels Signup and view all the answers

Which factor is necessary for the liver formation of five important clotting factors?

Vitamin K Signup and view all the answers

What can lead to serious bleeding tendencies due to subsequent insufficiency of coagulation factors in the blood?

Vitamin K deficiency Signup and view all the answers

Which disease can often cause decreased production of prothrombin and some other clotting factors?

Liver disease Signup and view all the answers

What is the most prevalent cause of vitamin K deficiency?

Obstruction of the bile ducts Signup and view all the answers

What does classic hemophilia (hemophilia A) result from?

Abnormality or deficiency of Factor VIII Signup and view all the answers

How many males in the United States have classic hemophilia?

1 in 10,000 males Signup and view all the answers

What does thrombocytopenia mean?

Low numbers of platelets in the blood Signup and view all the answers

Where does the bleeding usually occur in thrombocytopenia?

From small venules or capillaries Signup and view all the answers

What is an abnormal clot that develops in a blood vessel called?

Thrombus Signup and view all the answers

What are freely flowing clots known as?

Embolus Signup and view all the answers

What can initiate the clotting process if present on a vessel's endothelial surface?

Infections Signup and view all the answers

What can cause disseminated intravascular coagulation?

Large amounts of traumatized or dying tissue releasing tissue factor into the blood Signup and view all the answers

What is the main function of platelets in the formation of a platelet plug?

Releasing granules that contain multiple active factors Signup and view all the answers

What causes platelets to adhere to collagen in the tissues and to von Willebrand factor?

Secretion of large quantities of adenosine diphosphate (ADP) Signup and view all the answers

What is the role of thromboxane A2 in the mechanism of platelet plug formation?

Activating nearby platelets and promoting their stickiness Signup and view all the answers

Which factor is considered to be formed in two ways, the extrinsic pathway, and the intrinsic pathway?

Prothrombin activator Signup and view all the answers

What is the most important factor for preventing clotting in the normal vascular system?

Smoothness of the endothelial cell surface Signup and view all the answers

What anticoagulant acts by inactivating activated Factors V and VIII?

Protein C Signup and view all the answers

What is trapped in a clot along with other plasma proteins that will not become plasmin or cause lysis of the clot until it is activated?

Plasminogen Signup and view all the answers

Which protein binds thrombin and activates a plasma protein acting as an anticoagulant?

Thrombomodulin Signup and view all the answers

What is an important function of the endoplasmic reticulum and the Golgi apparatus in platelets?

Synthesizing various enzymes and especially storing large quantities of calcium ions Signup and view all the answers

What is the main role of growth factor released by platelets during platelet plug formation?

Causing vascular endothelial cells, vascular smooth muscle cells, and fibroblasts to multiply and grow Signup and view all the answers

What causes successively increasing numbers of platelets to be activated at the site of any opening in a blood vessel wall?

The secretion of large quantities of ADP and thromboxane by platelets Signup and view all the answers

Hemostasis Mechanisms Quiz

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Questions and Answers

What is the primary mechanism through which hemostasis is achieved when a blood vessel is severed?

Which factors contribute to the vascular constriction after a blood vessel has been cut or ruptured?

What is responsible for much of the vasoconstriction in smaller vessels?

What causes the smooth muscle in the blood vessel wall to contract immediately after a vessel has been cut or ruptured?

What are the main outcomes of hemostasis when a vessel is severed or ruptured?

What causes even more vasoconstriction in smaller vessels after they have been cut or ruptured?

Which factor is necessary for the liver formation of five important clotting factors?

What can lead to serious bleeding tendencies due to subsequent insufficiency of coagulation factors in the blood?

Which disease can often cause decreased production of prothrombin and some other clotting factors?

What is the most prevalent cause of vitamin K deficiency?

What does classic hemophilia (hemophilia A) result from?

How many males in the United States have classic hemophilia?

What does thrombocytopenia mean?

Where does the bleeding usually occur in thrombocytopenia?

What is an abnormal clot that develops in a blood vessel called?

What are freely flowing clots known as?

What can initiate the clotting process if present on a vessel's endothelial surface?

What can cause disseminated intravascular coagulation?

What is the main function of platelets in the formation of a platelet plug?

What causes platelets to adhere to collagen in the tissues and to von Willebrand factor?

What is the role of thromboxane A2 in the mechanism of platelet plug formation?

Which factor is considered to be formed in two ways, the extrinsic pathway, and the intrinsic pathway?

What is the most important factor for preventing clotting in the normal vascular system?

What anticoagulant acts by inactivating activated Factors V and VIII?

What is trapped in a clot along with other plasma proteins that will not become plasmin or cause lysis of the clot until it is activated?

Which protein binds thrombin and activates a plasma protein acting as an anticoagulant?

What is an important function of the endoplasmic reticulum and the Golgi apparatus in platelets?

What is the main role of growth factor released by platelets during platelet plug formation?

What causes successively increasing numbers of platelets to be activated at the site of any opening in a blood vessel wall?

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