Hemostasis Mechanisms Quiz
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Questions and Answers

What is the primary mechanism through which hemostasis is achieved when a blood vessel is severed?

  • Formation of a blood clot from blood coagulation
  • Growth of fibrous tissue into the blood clot
  • Formation of a platelet plug
  • Vascular constriction (correct)
  • Which factors contribute to the vascular constriction after a blood vessel has been cut or ruptured?

  • Local myogenic spasm
  • Autacoid factors from traumatized tissues and blood platelets
  • Nervous reflexes
  • All of the above (correct)
  • What is responsible for much of the vasoconstriction in smaller vessels?

  • Nervous reflexes initiated by pain nerve impulses
  • Autacoid factors from traumatized tissues and blood platelets
  • Local myogenic contraction of the blood vessels (correct)
  • Formation of a platelet plug
  • What causes the smooth muscle in the blood vessel wall to contract immediately after a vessel has been cut or ruptured?

    <p>Direct damage to the vascular wall</p> Signup and view all the answers

    What are the main outcomes of hemostasis when a vessel is severed or ruptured?

    <p>Formation of a blood clot as a result of blood coagulation and growth of fibrous tissue into the blood clot</p> Signup and view all the answers

    What causes even more vasoconstriction in smaller vessels after they have been cut or ruptured?

    <p>Local myogenic contraction of the blood vessels</p> Signup and view all the answers

    Which factor is necessary for the liver formation of five important clotting factors?

    <p>Vitamin K</p> Signup and view all the answers

    What can lead to serious bleeding tendencies due to subsequent insufficiency of coagulation factors in the blood?

    <p>Vitamin K deficiency</p> Signup and view all the answers

    Which disease can often cause decreased production of prothrombin and some other clotting factors?

    <p>Liver disease</p> Signup and view all the answers

    What is the most prevalent cause of vitamin K deficiency?

    <p>Obstruction of the bile ducts</p> Signup and view all the answers

    What does classic hemophilia (hemophilia A) result from?

    <p>Abnormality or deficiency of Factor VIII</p> Signup and view all the answers

    How many males in the United States have classic hemophilia?

    <p>1 in 10,000 males</p> Signup and view all the answers

    What does thrombocytopenia mean?

    <p>Low numbers of platelets in the blood</p> Signup and view all the answers

    Where does the bleeding usually occur in thrombocytopenia?

    <p>From small venules or capillaries</p> Signup and view all the answers

    What is an abnormal clot that develops in a blood vessel called?

    <p>Thrombus</p> Signup and view all the answers

    What are freely flowing clots known as?

    <p>Embolus</p> Signup and view all the answers

    What can initiate the clotting process if present on a vessel's endothelial surface?

    <p>Infections</p> Signup and view all the answers

    What can cause disseminated intravascular coagulation?

    <p>Large amounts of traumatized or dying tissue releasing tissue factor into the blood</p> Signup and view all the answers

    What is the main function of platelets in the formation of a platelet plug?

    <p>Releasing granules that contain multiple active factors</p> Signup and view all the answers

    What causes platelets to adhere to collagen in the tissues and to von Willebrand factor?

    <p>Secretion of large quantities of adenosine diphosphate (ADP)</p> Signup and view all the answers

    What is the role of thromboxane A2 in the mechanism of platelet plug formation?

    <p>Activating nearby platelets and promoting their stickiness</p> Signup and view all the answers

    Which factor is considered to be formed in two ways, the extrinsic pathway, and the intrinsic pathway?

    <p>Prothrombin activator</p> Signup and view all the answers

    What is the most important factor for preventing clotting in the normal vascular system?

    <p>Smoothness of the endothelial cell surface</p> Signup and view all the answers

    What anticoagulant acts by inactivating activated Factors V and VIII?

    <p>Protein C</p> Signup and view all the answers

    What is trapped in a clot along with other plasma proteins that will not become plasmin or cause lysis of the clot until it is activated?

    <p>Plasminogen</p> Signup and view all the answers

    Which protein binds thrombin and activates a plasma protein acting as an anticoagulant?

    <p>Thrombomodulin</p> Signup and view all the answers

    What is an important function of the endoplasmic reticulum and the Golgi apparatus in platelets?

    <p>Synthesizing various enzymes and especially storing large quantities of calcium ions</p> Signup and view all the answers

    What is the main role of growth factor released by platelets during platelet plug formation?

    <p>Causing vascular endothelial cells, vascular smooth muscle cells, and fibroblasts to multiply and grow</p> Signup and view all the answers

    What causes successively increasing numbers of platelets to be activated at the site of any opening in a blood vessel wall?

    <p>The secretion of large quantities of ADP and thromboxane by platelets</p> Signup and view all the answers

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