Hemostasis: Blood Coagulation and Vascular Spasms

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16 Questions

What is the first step in the process of hemostasis?

Vascular spasms (vasoconstriction at injured site)

What do activated platelets release to activate surrounding platelets and cause platelet plug formation?

ADP

What mediates vasoconstriction as the first reaction to vascular damage?

Released chemicals by traumatized tissues and blood platelets

What glycoprotein functions as a bridge between platelet and collagen fibrils of damaged tissue?

Von Willebrand factor

What is the function of vascular spasms in the process of hemostasis?

To prevent blood loss by reducing blood flow from the site of injury

What is the role of fibrous tissue in the process of hemostasis?

To close the hole in the vessel permanently

Which substance converts prothrombin to thrombin in the extrinsic pathway?

Factor VII

What is the main function of Factor VIII in blood coagulation?

Prevention of further blood loss

What is the role of Factor XII in blood coagulation?

Activation of factors XII and XI

What is the function of Ionized Calcium (Ca++) in the formation of a blood clot?

Conversion of Fibrinogen To Fibrin

Which factor is also known as Plasma Thromboplastin Antecedent?

Factor XI

What is the composition of a blood clot?

Blood cells, platelets, and plasma

Which factor is responsible for the activation of factor VII in the extrinsic pathway?

Factor III

What is the role of Factor IX in blood coagulation?

Conversion of Fibrinogen To Fibrin

What activates factor XII in the intrinsic pathway?

Injured endothelial cells

What converts prothrombin to thrombin in the presence of enough ionic Ca++ from platelets?

Conversion of Prothrombin To Thrombin

Learn about the process of hemostasis, which involves forming clots in injured blood vessels to prevent blood loss. This quiz covers the steps of hemostasis, including vascular spasms, platelet plug formation, blood clot formation, and the growth of fibrous tissue to close the vessel hole.

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