Hemoglobinopathies and Thalassemias Quiz

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Questions and Answers

What is the cause of thalassemias and related disorders?

  • Defects in the regulatory portion of the globin genes (correct)
  • Abnormal globin polypeptide chains
  • Mutant genes that cause the production of normal hemoglobins
  • Normal globin polypeptide chains

What happens to red blood cells in sickle cell anemia?

  • They lose their deformability and hemolize easily (correct)
  • They become larger and more flexible
  • They become more resistant to sickling
  • They become smaller and more rigid

What happens when an individual inherits identical abnormal genes from both parents?

  • They become homozygous (correct)
  • They become heterozygous
  • They develop major thalassemia
  • They develop minor thalassemia

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