Anemia and Hemoglobinopathies Quiz

Globin chain deletion leads to Sickle Cell Anemia

Differentiated by migration pattern in electrophoresis

Globin chain deletion is the root cause of Thalassemia.

Dithionite solubility test indicates intravascular hemolysis.

Increased Haptoglobin levels signify extravascular hemolysis.

High reticulocyte counts distinguish it from other hemolytic anemias.

Iron deficiency, folic acid deficiency, and vitamin B12 deficiency cause megaloblastic anemia.

Iron deficiency is the most common cause of non-megaloblastic anemia.

A condition characterized by low red blood cell count, causing symptoms like weakness and fatigue.

Iron deficiency anemia has low iron, sideroblastic anemia has normal iron, and anemia of chronic disease has high iron levels.

Differentiating them is vital for correct treatment and prevents worsening.

Folic acid deficiency shows hypersegmented neutrophils, while B12 deficiency shows oval macrocytes.

Hypersegmented Neutrophils are seen.

Oval macrocytes are seen.

A microscopic examination of blood cells to detect abnormalities.

An abnormality of iron metabolism characterized by ringed sideroblasts in the bone marrow.

Anemia that develops during or as a result of an ongoing illness.