Podcast
Questions and Answers
What is the most common cause of chronic anemia?
What is the most common cause of chronic anemia?
- Vitamin B12 deficiency
- Folate deficiency
- Iron deficiency (correct)
- Copper deficiency
Which of the following hematopoietic growth factors stimulates the production of granulocytes?
Which of the following hematopoietic growth factors stimulates the production of granulocytes?
- Cyanocobalamin
- Filgrastim (correct)
- Thrombopoietin
- Erythropoietin
What is the primary action of iron in the treatment of iron deficiency anemia?
What is the primary action of iron in the treatment of iron deficiency anemia?
- Synthesis of tetrahydrofolate
- Stimulation of erythropoietin production
- Increased hemoglobin production (correct)
- Increased absorption of folic acid
Which of the following is NOT a type of anemia?
Which of the following is NOT a type of anemia?
What is the primary action of Vitamin B12 in the synthesis of succinyl CoA?
What is the primary action of Vitamin B12 in the synthesis of succinyl CoA?
What is the primary indication for the use of Deferoxamine?
What is the primary indication for the use of Deferoxamine?
What determines the rate of iron transport into blood?
What determines the rate of iron transport into blood?
How does the transferrin-iron complex enter maturing erythroid cells?
How does the transferrin-iron complex enter maturing erythroid cells?
What is the primary function of ferritin in iron storage?
What is the primary function of ferritin in iron storage?
What is the primary route of iron elimination from the body?
What is the primary route of iron elimination from the body?
What is a common adverse effect of oral iron administration?
What is a common adverse effect of oral iron administration?
What is a common symptom of chronic anemia?
What is a common symptom of chronic anemia?
What is a rare but potential adverse effect of parenteral iron administration?
What is a rare but potential adverse effect of parenteral iron administration?
What is the primary role of hepcidin in the body?
What is the primary role of hepcidin in the body?
What is the effect of increased erythropoiesis on hepcidin production?
What is the effect of increased erythropoiesis on hepcidin production?
What is the role of HIF-2α in the adaptation to anemia?
What is the role of HIF-2α in the adaptation to anemia?
Why is free inorganic iron toxic to the body?
Why is free inorganic iron toxic to the body?
Why are dietary requirements for iron relatively low?
Why are dietary requirements for iron relatively low?
What is the risk of deep vein thrombosis in peri-surgery patients without prophylactic anticoagulation?
What is the risk of deep vein thrombosis in peri-surgery patients without prophylactic anticoagulation?
What is the primary function of Filgrastim?
What is the primary function of Filgrastim?
What is the effect of Sargramostim on hematopoietic stem cells?
What is the effect of Sargramostim on hematopoietic stem cells?
Which of the following is a multilineage growth factor?
Which of the following is a multilineage growth factor?
What is the effect of Filgrastim on phagocytic activity of neutrophils?
What is the effect of Filgrastim on phagocytic activity of neutrophils?
What is the primary goal of iron therapy in iron deficiency anemia?
What is the primary goal of iron therapy in iron deficiency anemia?
What is the consequence of acute iron toxicity?
What is the consequence of acute iron toxicity?
Which of the following is a contraindication for iron supplementation?
Which of the following is a contraindication for iron supplementation?
What is the therapy of choice for chronic iron toxicity?
What is the therapy of choice for chronic iron toxicity?
Why is ferrous iron preferred in oral iron therapy?
Why is ferrous iron preferred in oral iron therapy?
What is the precaution associated with iron supplements in Parkinson disease?
What is the precaution associated with iron supplements in Parkinson disease?
What is the primary function of transferrin in iron transport?
What is the primary function of transferrin in iron transport?
Where is iron stored in the liver?
Where is iron stored in the liver?
What is the daily amount of iron lost through elimination?
What is the daily amount of iron lost through elimination?
What is the mechanism of transferrin-iron complex entry into maturing erythroid cells?
What is the mechanism of transferrin-iron complex entry into maturing erythroid cells?
What is the effect of high iron stores on iron transport into blood?
What is the effect of high iron stores on iron transport into blood?
What is the significance of serum ferritin levels?
What is the significance of serum ferritin levels?
What is the primary treatment for chronic iron toxicity?
What is the primary treatment for chronic iron toxicity?
What is the main reason why ferrous iron is preferred in oral iron therapy?
What is the main reason why ferrous iron is preferred in oral iron therapy?
What is the consequence of severe acute iron toxicity?
What is the consequence of severe acute iron toxicity?
What is the precaution associated with iron supplements in patients with Parkinson disease?
What is the precaution associated with iron supplements in patients with Parkinson disease?
What is the primary goal of iron therapy in iron deficiency anemia?
What is the primary goal of iron therapy in iron deficiency anemia?
What is the primary indication for the use of parenteral iron therapy?
What is the primary indication for the use of parenteral iron therapy?
Which of the following patient groups may benefit from parenteral iron therapy?
Which of the following patient groups may benefit from parenteral iron therapy?
What is a common side effect of parenteral iron therapy?
What is a common side effect of parenteral iron therapy?
Which of the following is a disadvantage of parenteral iron therapy?
Which of the following is a disadvantage of parenteral iron therapy?
Which of the following medications may be used to prevent a flare of arthritis during IV iron infusion?
Which of the following medications may be used to prevent a flare of arthritis during IV iron infusion?
What is an advantage of parenteral iron therapy?
What is an advantage of parenteral iron therapy?
Which of the following is a contraindication for parenteral iron therapy?
Which of the following is a contraindication for parenteral iron therapy?
What is the effect of Filgrastim on hematopoietic stem cells?
What is the effect of Filgrastim on hematopoietic stem cells?
What is the difference between Filgrastim and Sargramostim?
What is the difference between Filgrastim and Sargramostim?
What is the risk of deep vein thrombosis in peri-surgery patients without prophylactic anticoagulation?
What is the risk of deep vein thrombosis in peri-surgery patients without prophylactic anticoagulation?
What is the effect of Sargramostim on T cells?
What is the effect of Sargramostim on T cells?
What type of growth factor is Filgrastim?
What type of growth factor is Filgrastim?
What is the enzyme responsible for catalyzing the reaction needed for purine and DNA synthesis?
What is the enzyme responsible for catalyzing the reaction needed for purine and DNA synthesis?
What is the primary function of dihydrofolate reductase in the body?
What is the primary function of dihydrofolate reductase in the body?
What is the recommended daily intake of folic acid in normal individuals?
What is the recommended daily intake of folic acid in normal individuals?
What is the consequence of giving folic acid supplements alone in patients with pernicious anemia without knowing whether they also have vitamin B12 deficiency?
What is the consequence of giving folic acid supplements alone in patients with pernicious anemia without knowing whether they also have vitamin B12 deficiency?
What is the therapeutic use of folic acid in pregnant women?
What is the therapeutic use of folic acid in pregnant women?
What is the primary storage site of folic acid in the body?
What is the primary storage site of folic acid in the body?
