Hematologic Agents and Blood Clotting
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Questions and Answers

Which drug is specifically used for treating Aplastic Anemia?

  • hydroxyurea
  • luspatercept-aamt
  • eltrombopag (correct)
  • crizanlizumab
  • Which of the following is a Bile Acid Sequestrant used for lowering lipids?

  • fenofibrate
  • atorvastatin
  • ezetimibe
  • cholestyramine (correct)
  • Which drug is classified as a Class III Antiarrhythmic?

  • digoxin
  • lidocaine
  • verapamil
  • amiodarone (correct)
  • Which of the following is an example of a Calcium Channel Blocker used in treating hypertension?

    <p>amlodipine (D)</p> Signup and view all the answers

    Which of the following agents is used as an antihemophilic factor?

    <p>antihemophilic factor Fc fusion protein (B)</p> Signup and view all the answers

    Which drug is a phosphodiesterase inhibitor used in treating heart failure?

    <p>milrinone (A)</p> Signup and view all the answers

    Which of the following is a loop diuretic?

    <p>furosemide (D)</p> Signup and view all the answers

    Which of the following is NOT a beta blocker?

    <p>doxazosin (D)</p> Signup and view all the answers

    Which of the following drugs is used to treat Benign Prostatic Hyperplasia?

    <p>tamsulosin (A)</p> Signup and view all the answers

    Which drug is a direct renin inhibitor used for hypertension?

    <p>aliskiren (B)</p> Signup and view all the answers

    Which of the following is an example of a HMG-CoA reductase inhibitor (statin)?

    <p>atorvastatin (B)</p> Signup and view all the answers

    Which of the following drugs is used for the treatment of Sickle Cell Anemia?

    <p>crizanlizumab (D)</p> Signup and view all the answers

    Which drug is a thrombin inhibitor?

    <p>bivalirudin (B)</p> Signup and view all the answers

    Which of the following is a potassium-sparing diuretic?

    <p>spironolactone (A)</p> Signup and view all the answers

    Which of the following is a direct-acting oral anticoagulant?

    <p>apixaban (B)</p> Signup and view all the answers

    Flashcards

    Erythropoiesis-Stimulating Agents

    Medications that promote red blood cell production.

    Iron Deficiency Anemia Treatment

    Medications like ferrous sulfate used to replenish iron.

    Folic Acid Derivatives

    Vitamins like folic acid that help treat megaloblastic anemia.

    Antiplatelet Agents

    Drugs that prevent blood clots by inhibiting platelets.

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    Anticoagulants

    Medications that prevent blood clotting.

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    Thrombolytic Agents

    Drugs used to dissolve blood clots.

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    Cardiac Glycoside

    A medication like digoxin used for heart failure.

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    Calcium Channel Blockers

    Medications that relax and widen blood vessels by preventing calcium entry.

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    Angiotensin-Converting Enzyme Inhibitors

    Drugs that lower blood pressure by relaxing blood vessels.

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    Thiazide Diuretics

    Drugs that help lower blood pressure by promoting urine output.

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    Antihemophilic Agents

    Medications that help to correct bleeding in hemophilia.

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    Urinary Tract Anti-infectives

    Medications that treat infections in the urinary tract.

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    Alpha-Adrenergic Blockers

    Drugs that treat BPH by relaxing muscles in the prostate.

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    Diuretics

    Medications that promote urination to remove excess fluid.

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    Beta-Blockers

    Drugs that manage heart conditions by reducing heart rate.

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    Study Notes

    Hematologic Agents

    • Erythropoiesis-Stimulating Agents: Darbepoetin alfa, Epoetin alfa, Methoxy polyethylene glycol-epoetin beta
    • Iron Deficiency Anemia Agents: Ferrous fumarate, Ferrous gluconate, Ferrous sulfate, Ferrous sulfate exsiccated, Ferumoxytol, Iron dextran, Iron sucrose, Sodium ferric gluconate complex
    • Agents for Other Anemias:
      • Megaloblastic Anemias: Folic Acid Derivatives (folic acid, leucovorin, levoleucovorin), Vitamin B12 (cyanocobalamin, hydroxocobalamin)
      • Sickle Cell Anemia: Crizanlizumab, Hydroxyurea, Voxelotor
      • Beta Thalassemia: Luspatercept-aamt
      • Aplastic Anemia: Eltrombopag

    Agents Affecting Blood Clotting

    • Antiplatelet Agents: Abciximab, Anagrelide, Aspirin, Cilostazol, Clopidogrel, Dipyridamole, Eptifibatide, Prasugrel, Ticagrelor, Ticlopidine, Tirofiban, Vorapaxar
    • Anticoagulants: Antithrombin, Apixaban, Argatroban, Betrixaban, Bivalirudin, Dabigatran, Dalteparin, Desirudin, Edoxaban, Enoxaparin, Fondaparinux, Heparin, Protein C concentrate, Rivaroxaban, Warfarin
    • Thrombolytic Agents: Alteplase, Reteplase, Tenecteplase
    • Anticoagulant Adjunctive Therapy: Coagulation factor Xa (recombinant), Idarucizumab, Protamine sulfate, Prothrombin complex concentrate, Vitamin K
    • Hemorrheologic Agent: Pentoxifylline

    Drugs Used to Control Bleeding

    • Antihemophilic Agents: Antihemophilic factor, Antihemophilic factor Fc fusion protein, Antihemophilic factor porcine sequence, Antiinhibitor coagulant complex, Coagulation factor VIIa, Factor IX, Factor IX complex, Factor XIII concentrate
    • Hemostatic Agents: Systemic aminocaproic acid, Topical absorbable gelatin, Human fibrin sealant, Microfibrillar collagen, Thrombin, Thrombin, recombinant

    Lipid-Lowering Agents

    • Bile Acid Sequestrants: Cholestyramine, Colesevelam, Colestipol
    • HMG–CoA Reductase Inhibitors (Statins): Atorvastatin, Fluvastatin, Lovastatin, Pitavastatin, Pravastatin, Rosuvastatin, Simvastatin
    • Cholesterol Absorption Inhibitor: Ezetimibe
    • PCSK9 Inhibitors: Alirocumab, Evolocumab
    • Other Lipid-Lowering Agents:
      • Fibrates: Fenofibrate, Fenofibric acid, Gemfibrozil
      • Vitamin B3 (Niacin): Niacin
      • Omega-3 Fatty Acids: Icosapent ethyl, Omega-3-acid ethyl esters, Omega-3-carboxylic acids
      • Other: Bempedoic acid, Lomitapide

    Antianginal Agents

    • Nitrates: Isosorbide dinitrate, Isosorbide mononitrate, Nitroglycerin
    • Beta-Blockers: Atenolol, Metoprolol, Nadolol, Propranolol
    • Calcium Channel Blockers: Amlodipine, Diltiazem, Nicardipine, Nifedipine, Verapamil
    • Piperazine Acetamide: Ranolazine

    Antiarrhythmic Agents

    • Class I Antiarrhythmics:
      • Class Ia: Disopyramide, Procainamide, Quinidine
      • Class Ib: Lidocaine, Mexiletine
      • Class Ic: Flecainide, Propafenone
    • Class II Antiarrhythmics: Acebutolol, Adenosine, Digoxin, Esmolol, Propranolol
    • Class III Antiarrhythmics: Amiodarone, Dofetilide, Dronedarone, Ibutilide, Sotalol
    • Class IV Antiarrhythmics: Diltiazem, Verapamil

    Agents for Heart Failure

    • Cardiac Glycoside: Digoxin
    • Phosphodiesterase Inhibitor: Milrinone
    • Hyperpolarization-Activated Cyclic Nucleotide–Gated Channel Blocker: Ivabradine
    • Angiotensin Receptor Neprilysin Inhibitor: Sacubitril/valsartan

    Antihypertensive Agents

    • Drugs Affecting the Renin–Angiotensin–Aldosterone System:
      • Angiotensin-Converting Enzyme Inhibitors: Benazepril, Captopril, Enalapril, Enalaprilat, Fosinopril, Lisinopril, Moexipril, Perindopril, Quinapril, Ramipril, Trandolapril
      • Angiotensin II Receptor Blockers: Azilsartan, Candesartan, Irbesartan, Losartan, Olmesartan, Telmisartan, Valsartan
      • Direct Renin Inhibitor: Aliskiren
    • Calcium-Channel Blockers: Amlodipine, Clevidipine, Diltiazem, Felodipine, Isradipine, Levamlodipine, Nicardipine, Nifedipine, Nisoldipine, Verapamil
    • Vasodilators: Hydralazine, Minoxidil, Nitroglycerin, Nitroprusside
    • Vasodilators for Pulmonary Artery Hypertension: Ambrisentan, Bosentan, Epoprostenol, Iloprost, Sildenafil, Tadalafil, Treprostinil
    • Other Antihypertensive Agents:
      • Diuretic Agents:
        • Thiazide and Thiazidelike Diuretics: Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone
        • Potassium-Sparing Diuretics: Amiloride, Eplerenone, Spironolactone, Triamterene
      • Sympathetic Nervous System Drugs:
        • Beta-Blockers: Acebutolol, Atenolol, Betaxolol, Bisoprolol, Esmolol, Metoprolol, Nadolol, Nebivolol, Pindolol, Propranolol, Timolol
        • Alpha- and Beta-Blockers: Carvedilol, Labetalol
        • Alpha-Adrenergic Blockers: Phenoxybenzamine, Phentolamine
        • Alpha1-Blockers: Doxazosin, Prazosin, Terazosin
        • Alpha2-Agonists: Clonidine, Guanfacine, Methyldopa
    • Other:

    Diuretics

    • Thiazide Diuretics and Thiazide-Like Diuretics:
      • Thiazide Diuretics: Chlorothiazide, Hydrochlorothiazide
      • Thiazide-Like Diuretics: Chlorthalidone, Indapamide, Metolazone
    • LOOP DIURETICS: Bumetanide, Ethacrynic acid, Furosemide, Torsemide
    • CARBONIC ANHYDRASE INHIBITORS: Acetazolamide, Dichlorphenamide, Methazolamide
    • POTASSIUM-SPARING DIURETICS: Amiloride, Eplerenone, Spironolactone, Triamterene
    • OSMOTIC DIURETICS: Mannitol

    Urinary Tract Drugs

    • Urinary Tract Antiinfectives: Fosfomycin, Methenamine, Nitrofurantoin, Trimethoprim, Trimethoprim–sulfamethoxazole
    • Urinary Tract Antispasmodics:
      • Anticholinergics: Darifenacin, Fesoterodine, Flavoxate, Oxybutynin, Solifenacin, Tolterodine, Trospium
      • Beta-Agonists: Mirabegron, Vibegro
    • Other Drugs Affecting Urinary Tract and Bladder:
      • Urinary Tract Analgesic: Phenazopyridine
      • Bladder Protectant: Pentosan polysulfate sodium
    • Drugs for Treating Benign Prostatic Hyperplasia:
      • Alpha-Adrenergic Blockers: Alfuzosin, Doxazosin, Silodosin, Tamsulosin, Terazosin
    • Drugs That Block Testosterone Production: Dutasteride, Finasteride

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    Description

    This quiz covers various hematologic agents, including erythropoiesis-stimulating agents and treatments for different types of anemia. Additionally, it explores agents affecting blood clotting, such as antiplatelet and anticoagulant medications. Test your knowledge on these crucial pharmacological substances and their applications in medicine.

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