Hematologic Disorders in Pregnancy

A disorder with a genetic predisposition toward venous embolism that alters clotting factors.

A product of increased risk of a venous thromboembolism (VTE) in pregnancy.

<p>Pulmonary embolism (PE) (A)</p> Signup and view all the answers

<p>A disorder of platelet alteration, resulting in a low platelet count.</p> Signup and view all the answers

<p>Less than 150,000 per microliter of blood.</p> Signup and view all the answers

<p>Less than 50,000 per microliter of blood.</p> Signup and view all the answers

<p>A disorder of abnormal antibody production that leads to thrombotic events.</p> Signup and view all the answers

<p>Recurrent pregnancy loss (A), Severe or early-onset preeclampsia (B), Abnormal fetal growth without explanation (C), Unexplained clot formation (D)</p> Signup and view all the answers

<p>Monthly fetal growth ultrasounds (A), Twice-weekly testing at term (B), Low-molecular-weight heparin (LMWH), heparin, or low-dose aspirin (C)</p> Signup and view all the answers

<p>At 36 weeks gestation.</p> Signup and view all the answers

<p>Hemoglobin &gt; 15 g/dL (A), Hematocrit &gt; 45% (B)</p> Signup and view all the answers

<p>Intrauterine growth restriction (IUGR).</p> Signup and view all the answers

<p>Maternal death (A), Increased preterm birth (B), Pregnancy loss (C), Fetal growth restriction (D)</p> Signup and view all the answers

<p>Glucose-6-phosphate dehydrogenase (G6PD) deficiency.</p> Signup and view all the answers

<p>X-linked, meaning it is more common in males.</p> Signup and view all the answers

<p>Nitrofurantoins (A), Analgesics (pain relievers) (B), Antimalarial compounds (C), Antipyretics (fever reducers) (D), Sulfonamides (E)</p> Signup and view all the answers

<p>Hereditary spherocytosis.</p> Signup and view all the answers

<p>Autosomal dominant, with variable penetrance.</p> Signup and view all the answers

<p>Hereditary spherocytosis is not dependent on a provoking agent or exposure.</p> Signup and view all the answers

<p>Hereditary elliptocytosis.</p> Signup and view all the answers

<p>Autosomal dominant.</p> Signup and view all the answers

<p>Every trimester (A), Urinary tract infections (UTIs) (B)</p> Signup and view all the answers

<p>Physician consultation (A), Discontinuation of the suspected exposure (B), Avoid oxidant medications (sulfonamides, nitrofurantoin) (C)</p> Signup and view all the answers

<p>Acute hemolytic crisis that can be precipitated by infection, trauma, or pregnancy.</p> Signup and view all the answers

<p>Osmotic fragility test (A), Hyperproliferative anemia (changes in CBC, reticulocytes) (B)</p> Signup and view all the answers

<p>Folate supplementation (A), Hemolytic crisis monitoring (B)</p> Signup and view all the answers

<p>Mild hemolytic state, similar to spherocytosis.</p> Signup and view all the answers

<p>Hyperproliferative anemia (changes in CBC, blood smear) (A), Osmotic fragility test (B)</p> Signup and view all the answers

<p>Thalassemia syndromes (quantitative changes in hemoglobin production).</p> Signup and view all the answers

<p>Structural hemoglobinopathies (sickle cell, Hb C, Hb E - qualitative changes in hemoglobin structure).</p> Signup and view all the answers

<p>Hb Gower II (A), Hb Gower I (B)</p> Signup and view all the answers

<p>HbF (most abundant) (A), Hb Portland (B)</p> Signup and view all the answers

<p>Alpha or beta peptide chains.</p> Signup and view all the answers

<p>Alpha major thalassemia.</p> Signup and view all the answers

<p>Alpha minor thalassemia.</p> Signup and view all the answers

<p>Beta major thalassemia.</p> Signup and view all the answers

<p>Beta minor thalassemia.</p> Signup and view all the answers

<p>Homozygous beta thalassemia major (Cooley's Anemia).</p> Signup and view all the answers

<p>Heterozygous beta thalassemia minor.</p> Signup and view all the answers

<p>Hemoglobin 8-10 g/dL (A), Low MCV (&lt;80 fL) (B), Unresponsive to iron supplementation (C)</p> Signup and view all the answers

<p>Prophylactic iron and folate (A), Second and third trimester antenatal fetal assessment (B), IUGR and oligohydramnios monitoring (C)</p> Signup and view all the answers

<p>Low serum hemoglobin (A), Low MCV (B)</p> Signup and view all the answers

<p>Preterm labor (PTL) (A), Intrauterine growth restriction (IUGR) (B)</p> Signup and view all the answers

<p>Vascular occlusion (A), Hemolysis (red blood cell destruction) (B), Increased susceptibility to infection (C)</p> Signup and view all the answers

<p>Folic acid supplementation.</p> Signup and view all the answers

<p>Pyelonephritis (kidney infection) (A), Urinary tract infections (UTIs) (quarterly screening) (B), Asymptomatic bacteriuria (C)</p> Signup and view all the answers

<p>Hemoglobin electrophoresis.</p> Signup and view all the answers

<p>The fetus dies (hemolytic anemia).</p> Signup and view all the answers

<p>Hemolytic disease of the newborn (similar to Rh(D)?)</p> Signup and view all the answers

A genetic disorder increasing risk for venous embolism by altering clotting factors.

A condition causing increased risk of venous thromboembolism (VTE) during pregnancy.

Deep vein thrombosis, more common during pregnancy.

Pulmonary Embolism, more common in labor and postpartum patients.

A disorder characterized by low platelet count.

The platelet count threshold for diagnosing thrombocytopenia.

Platelet count where disordered bleeding becomes likely.

A disorder of abnormal antibody production that results in thrombotic events.

Clinical presentation for antiphospholipid syndrome involving multiple miscarriages.

When fetal surveillance should begin for inherited thrombophilias.

High hemoglobin levels that may indicate poor volume expansion in pregnancy.

Intrauterine growth restriction linked to high hemoglobin or hematocrit in fetuses.

Anemia caused by an enzyme defect in red blood cells, triggered by various factors.

Hereditary pattern for disorders like hereditary spherocytosis.

Anemia resulting from structural defects in erythrocyte membranes, causing spherical RBCs.

Clinical presentation in hereditary spherocytosis, triggered by infections or stress.

Hereditary blood disorders causing abnormal hemoglobin production, leading to various symptoms.

A form of thalassemia causing severe disease in neonates and infertility in females.

An inherited disorder leading to sickle-shaped red blood cells and various health complications.

Test to identify hemoglobin types and detect hemoglobinopathies.

Antibodies like Duffy and Kell can hemolyze red blood cells in newborns.

Necessary support for individuals with sickle cell disease during pregnancy.

More common in G6PD deficiency, with recommended trimester screenings.

Increased risk in pregnancy with conditions like anemia or sickle cell disease.

Anemia marked by changes in complete blood count and reticulocytes.

Recommended to prevent anemia in thalassemia during pregnancy.

Common presentation in thalassemia disorders indicating microcytic anemia.

A condition where antigens cause issues in newborns, often linked to maternal Rh incompatibilities.