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Helicobacter Pylori: Historical Background Lecture Notes

10 Questions

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Helicobacter Pylori: Historical Background Lecture Notes

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Questions and Answers

What did Barry Marshall do to fulfill Koch's postulates regarding H. pylori?

Drank a H. pylori broth (correct)

Demonstrated H. pylori colonization in the human stomach mucus layer

Cultured H. pylori from gastric biopsies

Developed mild illness with gastritis

What was the morphological shape of H. pylori?

Stellate

Rod-shaped

Spherical

Spiral (correct)

What is the main characteristic of H. pylori with regard to its flagella?

Three tufts of unsheathed polar flagella

Four to seven tufts of sheathed polar flagella (correct)

Single polar flagellum

No flagella

What is the association of H. pylori infection according to the text?

Associated with increased risk for peptic ulcer disease Signup and view all the answers

What was the recognition awarded to Robin Warren and Barry Marshall for their research on H. pylori?

Nobel Prize for Physiology/Medicine Signup and view all the answers

What is the main pathogenetic factor in the development of gastric pathologies due to H. pylori infection?

Production of urease to hydrolyze urea to ammonia Signup and view all the answers

How does H. pylori primarily avoid the acidity in the gastric lumen?

It uses urease to hydrolyze urea to ammonia Signup and view all the answers

Which test is commonly used to detect H. pylori infection by looking for proteins associated with the bacteria in the stool?

Stool antigen test Signup and view all the answers

What is the purpose of the urea breath test in detecting H. pylori infection?

To measure the release of carbon molecules when you breathe out Signup and view all the answers

What is the role of H. pylori's flagella in its pathogenesis?

Movement away from the acidic environment Signup and view all the answers