Helicobacter Pylori: Historical Background Lecture Notes

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Questions and Answers

What did Barry Marshall do to fulfill Koch's postulates regarding H. pylori?

  • Drank a H. pylori broth (correct)
  • Demonstrated H. pylori colonization in the human stomach mucus layer
  • Cultured H. pylori from gastric biopsies
  • Developed mild illness with gastritis

What was the morphological shape of H. pylori?

  • Stellate
  • Rod-shaped
  • Spherical
  • Spiral (correct)

What is the main characteristic of H. pylori with regard to its flagella?

  • Three tufts of unsheathed polar flagella
  • Four to seven tufts of sheathed polar flagella (correct)
  • Single polar flagellum
  • No flagella

What is the association of H. pylori infection according to the text?

<p>Associated with increased risk for peptic ulcer disease (D)</p> Signup and view all the answers

What was the recognition awarded to Robin Warren and Barry Marshall for their research on H. pylori?

<p>Nobel Prize for Physiology/Medicine (A)</p> Signup and view all the answers

What is the main pathogenetic factor in the development of gastric pathologies due to H. pylori infection?

<p>Production of urease to hydrolyze urea to ammonia (B)</p> Signup and view all the answers

How does H. pylori primarily avoid the acidity in the gastric lumen?

<p>It uses urease to hydrolyze urea to ammonia (D)</p> Signup and view all the answers

Which test is commonly used to detect H. pylori infection by looking for proteins associated with the bacteria in the stool?

<p>Stool antigen test (C)</p> Signup and view all the answers

What is the purpose of the urea breath test in detecting H. pylori infection?

<p>To measure the release of carbon molecules when you breathe out (C)</p> Signup and view all the answers

What is the role of H. pylori's flagella in its pathogenesis?

<p>Movement away from the acidic environment (D)</p> Signup and view all the answers

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