H. Pylori Eradication and Treatment Goals
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Questions and Answers

What is the primary goal for a patient with an NSAID-induced ulcer?

  • To prevent ulcer recurrence
  • To eradicate H. pylori
  • To heal the ulcer as rapidly as possible (correct)
  • To relieve ulcer pain

What lifestyle modification should be implemented to manage ulcer symptoms?

  • Start smoking
  • Consume more spicy foods
  • Increase caffeine intake
  • Reduce stress (correct)

When should H. pylori eradication be performed in relation to antibiotic treatment?

  • 2 weeks after completion of antibiotic treatment
  • At least 4 weeks after completion of antibiotic treatment (correct)
  • Immediately after antibiotic treatment
  • 6 weeks after completion of antibiotic treatment

What is the goal of treatment for H. pylori-positive patients with an ulcer?

<p>To eradicate H. pylori and heal the ulcer (A)</p> Signup and view all the answers

What is the recommendation for patients with ulcer-related complications?

<p>Emergent surgery may be required (B)</p> Signup and view all the answers

What is the characteristic of an effective drug regimen for H. pylori infection?

<p>Effective, well-tolerated, convenient, and cost-effective (C)</p> Signup and view all the answers

What is the primary indication for switching to a COX-2 inhibitor?

<p>High-risk patients with ulcer complications (A)</p> Signup and view all the answers

What is the recommended course of action for patients with ulcers refractory to treatment?

<p>Upper endoscopy to confirm a nonhealing ulcer (C)</p> Signup and view all the answers

What is the indication for retreating with a double-dose of PPI?

<p>Patients with refractory ulcers despite a complete standard PPI course (C)</p> Signup and view all the answers

What is the timeframe for ulcer pain resolution when NSAIDs are discontinued?

<p>A few days (C)</p> Signup and view all the answers

What is the primary goal of monitoring patients during antiulcer therapy?

<p>Evaluate therapeutic outcomes (D)</p> Signup and view all the answers

What is the significance of persistent or recurrent symptoms within 14 days after the end of treatment?

<p>Failure of ulcer healing or H.pylori eradication (B)</p> Signup and view all the answers

What is the recommended treatment duration for second-line therapy in H.pylori eradication?

<p>10-14 days (D)</p> Signup and view all the answers

What should be done for patients who are H.pylori negative with NSAID-induced ulcers?

<p>Discontinue the NSAID and treat with a PPI, H2RA, or sucralfate (C)</p> Signup and view all the answers

Why is penicillin allergy testing recommended?

<p>Because many patients are not truly allergic (D)</p> Signup and view all the answers

What is the recommended treatment for patients failing clarithromycin triple therapy?

<p>Either bismuth quadruple therapy or the levofloxacin triple regimen for 14 days (A)</p> Signup and view all the answers

What is the primary advantage of PPIs in ulcer treatment?

<p>They provide more rapid symptom relief and ulcer healing (D)</p> Signup and view all the answers

What is the criterion for recommending 2-Clarithromycin triple therapy?

<p>H.pylori resistance exceeds 15% (D)</p> Signup and view all the answers

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