H. Pylori Eradication and Treatment Goals

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What is the primary goal for a patient with an NSAID-induced ulcer?

To prevent ulcer recurrence

To eradicate H. pylori

To heal the ulcer as rapidly as possible (correct)

To relieve ulcer pain

What lifestyle modification should be implemented to manage ulcer symptoms?

Start smoking

Consume more spicy foods

Increase caffeine intake

Reduce stress (correct)

When should H. pylori eradication be performed in relation to antibiotic treatment?

2 weeks after completion of antibiotic treatment

At least 4 weeks after completion of antibiotic treatment (correct)

Immediately after antibiotic treatment

6 weeks after completion of antibiotic treatment

What is the goal of treatment for H. pylori-positive patients with an ulcer?

To eradicate H. pylori and heal the ulcer Signup and view all the answers

What is the recommendation for patients with ulcer-related complications?

Emergent surgery may be required Signup and view all the answers

What is the characteristic of an effective drug regimen for H. pylori infection?

Effective, well-tolerated, convenient, and cost-effective Signup and view all the answers

What is the primary indication for switching to a COX-2 inhibitor?

High-risk patients with ulcer complications Signup and view all the answers

What is the recommended course of action for patients with ulcers refractory to treatment?

Upper endoscopy to confirm a nonhealing ulcer Signup and view all the answers

What is the indication for retreating with a double-dose of PPI?

Patients with refractory ulcers despite a complete standard PPI course Signup and view all the answers

What is the timeframe for ulcer pain resolution when NSAIDs are discontinued?

A few days Signup and view all the answers

What is the primary goal of monitoring patients during antiulcer therapy?

Evaluate therapeutic outcomes Signup and view all the answers

What is the significance of persistent or recurrent symptoms within 14 days after the end of treatment?

Failure of ulcer healing or H.pylori eradication Signup and view all the answers

What is the recommended treatment duration for second-line therapy in H.pylori eradication?

10-14 days Signup and view all the answers

What should be done for patients who are H.pylori negative with NSAID-induced ulcers?

Discontinue the NSAID and treat with a PPI, H2RA, or sucralfate Signup and view all the answers

Why is penicillin allergy testing recommended?

Because many patients are not truly allergic Signup and view all the answers

What is the recommended treatment for patients failing clarithromycin triple therapy?

Either bismuth quadruple therapy or the levofloxacin triple regimen for 14 days Signup and view all the answers

What is the primary advantage of PPIs in ulcer treatment?

They provide more rapid symptom relief and ulcer healing Signup and view all the answers

What is the criterion for recommending 2-Clarithromycin triple therapy?

H.pylori resistance exceeds 15% Signup and view all the answers