Harmless Antigens and Immune Response Disorders
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Questions and Answers

What is the most severe type of hypersensitivity reaction?

  • Type II
  • Type IV
  • Type I (correct)
  • Type III

Which effector cells are involved in Type I hypersensitivity reactions?

  • Natural killer cells
  • T lymphocytes
  • Tissue mast cells and circulating basophils (correct)
  • Neutrophils and macrophages

In Type II hypersensitivity, the reactions involve antibodies directed to antigens on the surface of specific cells or tissues, resulting in what process?

  • Inflammation
  • Cytolysis (correct)
  • Phagocytosis
  • Tissue fibrosis

Which of the following is NOT a mediator involved in Type I hypersensitivity reactions?

<p>Complement proteins (B)</p> Signup and view all the answers

Which condition is associated with recurrent pyogenic infections and urticaria?

<p>Systemic lupus erythematosus (SLE) (C)</p> Signup and view all the answers

What is the time frame for manifesting signs and symptoms in Type II hypersensitivity reactions?

<p>5-8 hours (B)</p> Signup and view all the answers

Which hypersensitivity reaction is characterized by the induction of cross-linking of IgE bound to mast cells?

<p>Type I (D)</p> Signup and view all the answers

Which hypersensitivity reaction type involves cell-mediated antibody-dependent lysis by IgG and IgM?

<p>Type II (B)</p> Signup and view all the answers

What type of hypersensitivity reaction is associated with blood transfusion reactions and autoimmune hemolytic anemia?

<p>Type II (D)</p> Signup and view all the answers

Which of the following clinical states is NOT associated with anaphylaxis?

<p>Goodpasture syndrome (B)</p> Signup and view all the answers

Which condition has an onset of signs and symptoms within 2-8 hours after exposure?

<p>Serum sickness (D)</p> Signup and view all the answers

Which hypersensitivity reaction involves the deposition of immune complexes at various sites?

<p>Type III (A)</p> Signup and view all the answers

What is the main mechanism behind the Arthus reaction?

<p>Memory TH1 cells release cytokines (A)</p> Signup and view all the answers

Which type of hypersensitivity reaction involves soluble antigens?

<p>Type III (B)</p> Signup and view all the answers

In which associated disease does pre-sensitized lymphocytes lead to an inflammatory reaction a couple of days after contact with the offending plant material?

<p>Contact dermatitis (B)</p> Signup and view all the answers

Which disease is NOT associated with Type IV hypersensitivity reactions?

<p>Systemic lupus (C)</p> Signup and view all the answers

What mechanism characterizes Type II hypersensitivity reactions leading to cell destruction?

<p>Antibodies directed against cell surface antigens (D)</p> Signup and view all the answers

Which disease involves complement lysis as a mechanism of destruction?

<p>Glomerulonephritis (D)</p> Signup and view all the answers

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