Harmless Antigens and Immune Response Disorders

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What is the most severe type of hypersensitivity reaction?

Type II

Type IV

Type I (correct)

Type III

Which effector cells are involved in Type I hypersensitivity reactions?

Natural killer cells

T lymphocytes

Tissue mast cells and circulating basophils (correct)

Neutrophils and macrophages

In Type II hypersensitivity, the reactions involve antibodies directed to antigens on the surface of specific cells or tissues, resulting in what process?

Inflammation

Cytolysis (correct)

Phagocytosis

Tissue fibrosis

Which of the following is NOT a mediator involved in Type I hypersensitivity reactions?

Complement proteins Signup and view all the answers

Which condition is associated with recurrent pyogenic infections and urticaria?

Systemic lupus erythematosus (SLE) Signup and view all the answers

What is the time frame for manifesting signs and symptoms in Type II hypersensitivity reactions?

5-8 hours Signup and view all the answers

Which hypersensitivity reaction is characterized by the induction of cross-linking of IgE bound to mast cells?

Type I Signup and view all the answers

Which hypersensitivity reaction type involves cell-mediated antibody-dependent lysis by IgG and IgM?

Type II Signup and view all the answers

What type of hypersensitivity reaction is associated with blood transfusion reactions and autoimmune hemolytic anemia?

Type II Signup and view all the answers

Which of the following clinical states is NOT associated with anaphylaxis?

Goodpasture syndrome Signup and view all the answers

Which condition has an onset of signs and symptoms within 2-8 hours after exposure?

Serum sickness Signup and view all the answers

Which hypersensitivity reaction involves the deposition of immune complexes at various sites?

Type III Signup and view all the answers

What is the main mechanism behind the Arthus reaction?

Memory TH1 cells release cytokines Signup and view all the answers

Which type of hypersensitivity reaction involves soluble antigens?

Type III Signup and view all the answers

In which associated disease does pre-sensitized lymphocytes lead to an inflammatory reaction a couple of days after contact with the offending plant material?

Contact dermatitis Signup and view all the answers

Which disease is NOT associated with Type IV hypersensitivity reactions?

Systemic lupus Signup and view all the answers

What mechanism characterizes Type II hypersensitivity reactions leading to cell destruction?

Antibodies directed against cell surface antigens Signup and view all the answers

Which disease involves complement lysis as a mechanism of destruction?

Glomerulonephritis Signup and view all the answers