Harmless Antigens and Immune Response Disorders
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Questions and Answers

What is the most severe type of hypersensitivity reaction?

  • Type II
  • Type IV
  • Type I (correct)
  • Type III
  • Which effector cells are involved in Type I hypersensitivity reactions?

  • Natural killer cells
  • T lymphocytes
  • Tissue mast cells and circulating basophils (correct)
  • Neutrophils and macrophages
  • In Type II hypersensitivity, the reactions involve antibodies directed to antigens on the surface of specific cells or tissues, resulting in what process?

  • Inflammation
  • Cytolysis (correct)
  • Phagocytosis
  • Tissue fibrosis
  • Which of the following is NOT a mediator involved in Type I hypersensitivity reactions?

    <p>Complement proteins</p> Signup and view all the answers

    Which condition is associated with recurrent pyogenic infections and urticaria?

    <p>Systemic lupus erythematosus (SLE)</p> Signup and view all the answers

    What is the time frame for manifesting signs and symptoms in Type II hypersensitivity reactions?

    <p>5-8 hours</p> Signup and view all the answers

    Which hypersensitivity reaction is characterized by the induction of cross-linking of IgE bound to mast cells?

    <p>Type I</p> Signup and view all the answers

    Which hypersensitivity reaction type involves cell-mediated antibody-dependent lysis by IgG and IgM?

    <p>Type II</p> Signup and view all the answers

    What type of hypersensitivity reaction is associated with blood transfusion reactions and autoimmune hemolytic anemia?

    <p>Type II</p> Signup and view all the answers

    Which of the following clinical states is NOT associated with anaphylaxis?

    <p>Goodpasture syndrome</p> Signup and view all the answers

    Which condition has an onset of signs and symptoms within 2-8 hours after exposure?

    <p>Serum sickness</p> Signup and view all the answers

    Which hypersensitivity reaction involves the deposition of immune complexes at various sites?

    <p>Type III</p> Signup and view all the answers

    What is the main mechanism behind the Arthus reaction?

    <p>Memory TH1 cells release cytokines</p> Signup and view all the answers

    Which type of hypersensitivity reaction involves soluble antigens?

    <p>Type III</p> Signup and view all the answers

    In which associated disease does pre-sensitized lymphocytes lead to an inflammatory reaction a couple of days after contact with the offending plant material?

    <p>Contact dermatitis</p> Signup and view all the answers

    Which disease is NOT associated with Type IV hypersensitivity reactions?

    <p>Systemic lupus</p> Signup and view all the answers

    What mechanism characterizes Type II hypersensitivity reactions leading to cell destruction?

    <p>Antibodies directed against cell surface antigens</p> Signup and view all the answers

    Which disease involves complement lysis as a mechanism of destruction?

    <p>Glomerulonephritis</p> Signup and view all the answers

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