Hallmark 1: Replicative Immortality in Cancer Cells
12 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the hallmark associated with cancer cells converting glucose to lactate irrespective of oxygen?

  • Hallmark 6 - Altered Metabolism (correct)
  • Hallmark 7 - Avoiding Immune Destruction
  • Hallmark 5 - Sustained Proliferation
  • Hallmark 8 - Tumor Promoting Inflammation
  • Which immune cell type do cancer cells inhibit to avoid immune destruction?

  • B cells
  • Macrophages
  • Natural killer cells
  • T lymphocytes (correct)
  • What process do tumor cells induce to survive by creating new blood vessels from pre-existing ones?

  • Metastasis
  • Angiogenesis (correct)
  • Apoptosis
  • Glycolysis
  • How do normal cells react to abundant DNA damage and stress compared to cancer cells?

    <p>Normal cells initiate apoptosis</p> Signup and view all the answers

    Which hallmark describes the ability of cancer cells to divert metabolites for useful processes such as mitosis?

    <p>Hallmark 6 - Altered Metabolism</p> Signup and view all the answers

    What factor allows tumor cells to break through the extracellular matrix during invasion?

    <p>Over-active oncogenes</p> Signup and view all the answers

    What characteristic allows cancer cells to greatly exceed the Hayflick's limit and continue to undergo mitosis?

    <p>Elongation of telomeres using telomerase</p> Signup and view all the answers

    What is a key characteristic of cancer cells related to Genome Instability?

    <p>Possessing an abnormal number of chromosomes per cell</p> Signup and view all the answers

    Which gene functions as a central regulator of cell death by stopping the cell cycle upon detection of DNA damage?

    <p>p53 Tumor Suppressor Gene</p> Signup and view all the answers

    Why do most cancer cells avoid normal growth suppressor signals in the G1 checkpoint?

    <p>To continue proliferating</p> Signup and view all the answers

    What mechanism allows cancer cells to resist cell death?

    <p>Being able to evade apoptosis</p> Signup and view all the answers

    What is the enzyme that cancer cells use to elongate their telomeres?

    <p>Telomerase</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser