Gut Tube and Body Cavities Overview

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Questions and Answers

What structure do the pleuroperitoneal membranes form in the diaphragm?

  • Crura of the diaphragm
  • Muscular components
  • Central tendon (correct)
  • Phrenic nerves

From which cervical segments do the muscle cells of the diaphragm originate?

  • C4—C6
  • C1—C2
  • C5—C7
  • C3—C5 (correct)

Which spinal nerve structure is responsible for the innervation of the diaphragm?

  • Dorsal root ganglia
  • Cervical sympathetic trunk
  • Lateral horns
  • Ventral primary rami (correct)

What developmental process causes the diaphragm to move to its final location?

<p>Differential growth (C)</p> Signup and view all the answers

Which of the following is NOT involved in the formation of the diaphragm?

<p>Mesentery of the stomach (A)</p> Signup and view all the answers

What structure forms the gut tube during the early development of the embryo?

<p>Endoderm (C)</p> Signup and view all the answers

Which layer of the lateral plate mesoderm is adjacent to the surface ectoderm?

<p>Parietal layer (C)</p> Signup and view all the answers

What is the primitive body cavity composed of?

<p>Space between visceral and parietal layers (C)</p> Signup and view all the answers

Which of the following components plays a role in forming the skull and vertebrae?

<p>Paraxial mesoderm (B)</p> Signup and view all the answers

What are the two layers formed from the differentiation of lateral plate mesoderm?

<p>Somatic and visceral (D)</p> Signup and view all the answers

During the process of neurulation, which structure rolls up to form the brain and spinal cord?

<p>Neural plate (A)</p> Signup and view all the answers

What is the relationship between the visceral layer and the gut tube?

<p>It is adjacent and connected to the gut tube (B)</p> Signup and view all the answers

Which of the following regions is NOT subdivided at the early stage of embryo development?

<p>Primitive body cavity (B)</p> Signup and view all the answers

What is the primary function of the septum transversum during embryonic development?

<p>To support the development of the lungs (B)</p> Signup and view all the answers

How do the pleuropericardial membranes contribute to the thoracic cavity?

<p>They create the definitive pericardial cavity (D)</p> Signup and view all the answers

What separates the pleural cavities from the pericardial cavity in adults?

<p>The pleuropericardial membranes (C)</p> Signup and view all the answers

What happens to the pericardioperitoneal canals as lung buds expand?

<p>They become too small to contain the expanding lungs (C)</p> Signup and view all the answers

What initiates the formation of the definitive walls of the thorax?

<p>The expansion of the lung buds (C)</p> Signup and view all the answers

Which structure is responsible for the communication between the pleural and peritoneal cavities during development?

<p>The pleuroperitoneal folds (C)</p> Signup and view all the answers

What structural change occurs to the pleuropericardial membranes after forming?

<p>They fuse with the root of the lungs (D)</p> Signup and view all the answers

Which component of mesodermal tissue contributes to the formation of the diaphragm?

<p>Splanchnic mesoderm surrounding the heart (C)</p> Signup and view all the answers

What forms the lateral body wall folds during the fourth week of embryonic development?

<p>Parietal layer of lateral plate mesoderm, overlying ectoderm, and adjacent somite cells (D)</p> Signup and view all the answers

Which layer of mesoderm grows ventrally to assist in closing the gut tube?

<p>Endoderm layer (A)</p> Signup and view all the answers

What structure is formed from the connection between the midgut region and the yolk sac?

<p>Vitelline duct (A)</p> Signup and view all the answers

Which of the following best describes the continuous relationship between the parietal and visceral layers of mesoderm?

<p>They are continuous at the junction of the gut tube and posterior body wall (C)</p> Signup and view all the answers

Which cavity is lined by the parietal layer of the serous membranes?

<p>All of the above (D)</p> Signup and view all the answers

What type of mesentery exists only from the caudal foregut to the upper portion of the duodenum?

<p>Ventral mesentery (B)</p> Signup and view all the answers

What occurs with the Vitelline duct during the second to third months of gestation?

<p>It degenerates with the yolk sac (B)</p> Signup and view all the answers

Which layer forms the visceral layer of the serous membranes that cover the abdominal organs?

<p>Visceral layer of the lateral plate mesoderm (D)</p> Signup and view all the answers

Flashcards

Neurulation

The process of the neural plate rolling up to form the brain and spinal cord.

Gut Tube Formation

The formation of the gut tube, occurring simultaneously with neurulation.

Mesoderm

The middle layer of the trilaminar embryonic disc, responsible for forming key structures like the body cavity.

Lateral Plate Mesoderm

The part of the mesoderm that splits into visceral and parietal layers, forming the body cavity.

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Parietal (Somatic) Layer

The layer of the lateral plate mesoderm that forms the body wall.

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Visceral (Splanchnic) Layer

The layer of the lateral plate mesoderm that forms the internal linings of the organs.

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Primitive Body Cavity

The space between the parietal and visceral layers of the lateral plate mesoderm, forming the initial body cavity.

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Body Cavity Subdivision

The process of the primitive body cavity being divided into the pericardial, pleural, and abdomino-pelvic cavities.

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Pleuroperitoneal membrane

A thin membrane that forms during development and contributes to the formation of the diaphragm, separating the chest and abdominal cavities.

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Central tendon of diaphragm origin

The central tendon of the diaphragm is developed from the fusion of the two pleuroperitoneal membranes.

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Crura of the diaphragm origin

The crura of the diaphragm, which are muscle attachments, are formed from the mesentery of the esophagus.

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Diaphragm muscle origin

Muscle fibers that make up the diaphragm originate from cervical spinal segments C3-C5. These segments were responsible for diaphragm development in the fourth week.

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Phrenic nerve origin

The phrenic nerve, which controls the diaphragm, originates from the ventral rami of spinal nerves C3-C5.

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Septum transversum

A thick mesodermal tissue dividing the thoracic cavity from the yolk sac.

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Pericardioperitoneal canals

Openings on either side of the foregut, connecting the thoracic and abdominal cavities.

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Lung buds

Outgrowths of the respiratory system that expand into the pericardioperitoneal canals.

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Pleuropericardial folds

Folds of mesoderm that form the definitive thoracic wall and the pleuropericardial membranes.

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Pleuropericardial membranes

Membranes extending from the pleuropericardial folds, containing the common cardinal veins and phrenic nerves.

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Pleuroperitoneal folds

Crescent-shaped folds that partially close the opening between the pleural and peritoneal cavities.

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Diaphragm

The muscle that separates the chest and abdominal cavities, formed from multiple structures during development.

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Development of the thoracic cavity

The process of separating the thoracic and abdominal cavities by forming the diaphragm and pleural membranes.

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Body Cavity Formation

The development of the body cavity in the early embryo, involving the infolding of the lateral body wall folds to create the peritoneal, pleural, and pericardial cavities.

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Parietal and Visceral Layers

The two layers of mesoderm: the parietal layer lining the body wall and the visceral layer covering organs.

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Serous Membranes

Thin sheets of mesoderm that line body cavities and cover organs.

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Dorsal Mesentery

The structure that suspends the gut tube from the posterior body wall into the peritoneal cavity, formed from the fusion of the parietal and visceral layers of mesoderm.

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Ventral Mesentery

The structure that exists only in the caudal foregut and upper duodenum, resulting from the thinning of mesoderm in the septum transversum.

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Vitelline (Yolk Sac) Duct

The connection between the midgut region and the yolk sac, incorporated into the umbilical cord and eventually degenerating.

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Gut Tube Junction with Posterior Body Wall

The connection between the gut and the posterior body wall, formed by the fusion of the parietal and visceral layers of the lateral plate mesoderm.

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Study Notes

Gut Tube and Body Cavities

  • The gut tube forms from the endoderm layer, rolling down
  • The neural tube forms from the ectoderm layer, rolling up
  • Mesoderm holds the two tubes together
  • Mesoderm splits into visceral and parietal layers
  • Visceral layer connects to the gut tube
  • Parietal layer forms the lateral body wall folds
  • The space between visceral and parietal layers is the primitive body cavity
  • The primitive body cavity is initially continuous
  • The primitive cavity later divides into pericardial, pleural, and abdomino-pelvic regions

Formation of the Body Cavity

  • At the end of the 3rd week, intraembryonic mesoderm differentiates
  • Paraxial mesoderm forms somitomeres/somites
  • Intermediate mesoderm contributes to the urogenital system
  • Lateral plate mesoderm forms the body cavity
  • Mesoderm divides into parietal and visceral layers
  • Parietal layer is adjacent to surface ectoderm and extra-embryonic parietal mesoderm
  • Visceral layer is adjacent to endoderm of gut tube and extra-embryonic visceral mesoderm
  • Somatopleure = parietal layer + ectoderm
  • Splanchnopleure = visceral layer + endoderm
  • The space between these layers forms the primitive body cavity

Serous Membranes

  • Cells of parietal layer become mesothelial, forming parietal serous membranes
  • Cells of visceral layer form visceral serous membranes
  • Visceral and parietal layers are continuous, forming the dorsal mesentery
  • Dorsal mesentery extends from foregut to hindgut
  • Ventral mesentery extends from foregut to duodenum
  • Mesenteries – connective tissue scaffolds for blood vessels, nerves, and lymphatics

Diaphragm and Thoracic Cavity

  • The septum transversum is a mesodermal plate between the thoracic & yolk sac stalks.
  • The septum separates the thoracic & abdominal cavities
  • Initially, the septum leaves pericardioperitoneal canals
  • Lung buds grow and expand laterally, forcing the pericardioperitoneal canals to shrink.
  • The lungs expand into the body wall dorsally, laterally, and ventrally
  • Ventral and lateral expansion is posterior to the pleuropericardial folds

Formation of the Diaphragm

  • Diaphragm folds project into the primitive thoracic cavity
  • The folds consist of mesoderm of the body wall
  • Two components: definitive thorax wall and pleuropericardial membranes containing cardinal veins & phrenic nerves
  • Descent of the heart and sinus venosus cause pleuropericardial membranes to shift
  • The membranes fuse, creating the thoracic cavity, pericardial cavity and two pleural cavities.
  • Diaphragm is derived from pleuroperitoneal membranes, cervical muscle components, and esophageal mesentery

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