5 Questions
What is the primary function of the gut microbiome bacteria in relation to the compounds produced?
To produce compounds as by-products of feeding on digestive remnants.
What is the main goal of the researchers in identifying microbial by-products?
To tap into their potential to treat diseases by regulating nuclear receptors.
What is the name of the receptor that the researchers found small molecules in the gut microbiome can regulate?
Constitutive androstane receptor (CAR)
What are the names of the two compounds found in the metabolite screen that regulated CAR in both human and mouse liver?
Diindolylmethane (DIM) and diindolylethane (DIE)
What are some potential diseases that could be treated by leveraging the compounds found in the gut microbiome?
Diabetes, fatty liver disease, and small intestine ulcerative colitis
Discover the role of the gut microbiome in reducing inflammation and digestive issues. Learn how researchers are harnessing the power of microbial by-products to regulate nuclear receptors and potentially treat disease.
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