Growth Factor Receptors and Tyrosine Kinase Activity

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Growth factor receptors, including those for insulin, IGF and ______, possess tyrosine kinase activity.

EGF

The growth factor receptors, including those for insulin and ______, possess tyrosine kinase activity.

IGF

The receptors contain an amino terminal surface exposed ______ domain.

ligand-binding

Autophosphorylation is a result of ______ binding.

ligand

The receptors possess a single ______ domain and a carboxyl terminal catalytic domain.

membrane-spanning

Understand the structure and function of growth factor receptors, including insulin, IGF, and EGF receptors, and how they possess tyrosine kinase activity. Learn about the mechanism of ligand binding and autophosphorylation. Test your knowledge on the role of tyrosine kinase in cell signaling.

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