12 Questions
What is the most distinctive feature of Group B Streptococcus (Streptococcus agalactiae)?
It is gram positive and catalase negative
Which test is used to specifically identify Group B Streptococcus?
Hippurate hydrolysis test
What is the major virulence factor of Group B Streptococcus?
Polysaccharide capsule
Which of the following is the primary mode of transmission for Group B Streptococcus?
Vertical transmission from mother to neonate
What is the recommended prevention strategy for Group B Streptococcus infection in newborns?
Screening pregnant women at 35 weeks and providing intrapartum antibiotic prophylaxis
Which antibiotic regimen is typically used to treat Group B Streptococcus infections in newborns?
Ampicillin and an aminoglycoside
What is the significance of the purple color in the image?
It indicates that Group B Streptococcus is gram-positive and catalase-negative
What does the 'Hippo doll' in the image represent?
The positive hippurate test, which is specific to Group B Streptococcus
What does the 'Camp tent' in the image signify?
The cAMP test, which shows an increasing zone of hemolysis
Which of the following is the primary mode of transmission for Group B Streptococcus?
Vertical transmission from mother to newborn during childbirth
Which of the following clinical manifestations is Group B Streptococcus most likely to cause in newborns?
Sepsis
What is the recommended prevention strategy for Group B Streptococcus infection in newborns?
Screening for Group B Streptococcus carriage at 35-37 weeks of pregnancy and providing intrapartum antibiotic prophylaxis
Study Notes
Group B Strep (Strep agalactiae)
- Gram positive, catalase negative
- Causes major infections in newborns
Features
- Positive hippurate test, hydrolyzes Na+ hippurate
- Polysaccharide capsule is a virulence factor
- cAMP test positive, has an increasing zone of hemolysis
- Beta-hemolytic
- Bacitracin resistant
Diseases
- Most likely to cause meningitis in neonates
- Most likely to cause sepsis in neonates
- Causes pneumonia
Transmission
- Transmission of group B strep through vaginal canal
- Transmission through GI Tract
Prevention
- Mothers are cultured for Group B strep at 35 weeks
- Penicillin is given to mom intrapartum to prevent Group B Strep
Treatment
- Give baby ampicillin with an aminoglycoside or cephalosporin
Test your knowledge on the features of Group B Streptococcus (Strep agalactiae) infection, particularly in newborns. Learn about its gram stain, catalase test, hippurate test, capsule structure, cAMP test, and more.
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