Gram-Negative Bacteria Overview
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Questions and Answers

What type of infections are primarily caused by Legionella?

  • Gastrointestinal infections
  • Urinary tract infections
  • Skin infections
  • Respiratory tract infections (correct)
  • Which disease is caused by members of the genus Brucella in humans?

  • Rabbit fever
  • Legionnaires' disease
  • Undulant fever (correct)
  • Whooping cough
  • Pseudomonas aeruginosa is primarily known as which type of pathogen?

  • Opportunistic pathogen (correct)
  • Primary pathogen
  • Commensal pathogen
  • Zoonotic pathogen
  • What is tularemia, and what primarily causes it?

    <p>A zoonosis caused by Francisella tularensis</p> Signup and view all the answers

    What characteristic is true for Bacteroides?

    <p>Anaerobic Gram-negative rods associated with peritonitis</p> Signup and view all the answers

    What is the most clinically significant species of the genus Yersinia?

    <p>Y.pestis</p> Signup and view all the answers

    What disease is primarily caused by Yersinia pestis?

    <p>Bubonic plague</p> Signup and view all the answers

    Which organism is known for causing acute gastritis and ulcers?

    <p>Helicobacter pylori</p> Signup and view all the answers

    What common infection is H.influenzae primarily known for causing in infants?

    <p>Meningitis</p> Signup and view all the answers

    Which of the following species is associated with whooping cough?

    <p>Bordetella pertussis</p> Signup and view all the answers

    What type of plague presents with more severe symptoms during epidemics?

    <p>Pneumonic plague</p> Signup and view all the answers

    What is a common symptom associated with cholera?

    <p>Profuse watery diarrhea</p> Signup and view all the answers

    What is the mechanism of motility for Helicobacter species?

    <p>Flagella</p> Signup and view all the answers

    Which organism is primarily associated with infections outside the gastrointestinal tract?

    <p>Klebsiella</p> Signup and view all the answers

    Which of the following has the capability to cause both gastrointestinal and extraintestinal diseases?

    <p>Yersinia</p> Signup and view all the answers

    What is the significance of fimbriae in Escherichia coli?

    <p>They are important for adherence to mucosal surfaces.</p> Signup and view all the answers

    Which of the following is a pathogenic species of the genus Neisseria?

    <p>Neisseria meningitidis</p> Signup and view all the answers

    Which group of organisms are known to be important nosocomial pathogens?

    <p>Acinetobacter</p> Signup and view all the answers

    What is the primary mode of transmission for Neisseria gonorrhoeae?

    <p>Sexual contact</p> Signup and view all the answers

    Which of the following statements is true regarding Neisseria gonorrhoeae?

    <p>It is a gram-negative diplococcus.</p> Signup and view all the answers

    Which of these genera mainly causes diseases in the gastrointestinal tract?

    <p>Vibrio and Helicobacter</p> Signup and view all the answers

    What characteristic do all the organisms in the gastrointestinal Gram-negative rods group share?

    <p>They are true facultative anaerobes.</p> Signup and view all the answers

    Which one of these organisms is included in the category of gram-negative rods?

    <p>Campylobacter</p> Signup and view all the answers

    Which of the following is NOT a pathogen mentioned in the document?

    <p>Lactobacillus</p> Signup and view all the answers

    Neisseria species are primarily classified as which type of bacteria?

    <p>Gram-negative cocci</p> Signup and view all the answers

    Fecal contamination is frequently important in the transmission of which type of microorganisms?

    <p>Gastrointestinal pathogens</p> Signup and view all the answers

    What is a common clinical observation associated with Neisseria gonorrhoeae?

    <p>Presence in neutrophils</p> Signup and view all the answers

    Which species is frequently confused with Neisseria gonorrhoeae under the microscope?

    <p>Neisseria meningitidis</p> Signup and view all the answers

    Which of the following infections does Neisseria meningitidis commonly cause?

    <p>Meningitis</p> Signup and view all the answers

    What is the most important virulence factor of N.meningitidis?

    <p>Polysaccharide capsule</p> Signup and view all the answers

    Which of the following vaccines is a conjugate meningococcal vaccine approved for use in adolescents and adults?

    <p>MCV4 vaccine</p> Signup and view all the answers

    What are common symptoms that develop in individuals with meningococcal infections?

    <p>Severe headache and vomiting</p> Signup and view all the answers

    How quickly can meningococcal septicemia develop in a previously healthy individual?

    <p>In less than 12 hours</p> Signup and view all the answers

    What is the initial site of colonization for N.meningitidis?

    <p>Nasopharynx</p> Signup and view all the answers

    Which serogroups are included in the MCV4 vaccine?

    <p>A, C, W-135, Y</p> Signup and view all the answers

    What can happen within several hours of showing initial meningitis symptoms?

    <p>Onset of coma</p> Signup and view all the answers

    What commonly accompanies joint symptoms in meningococcal infections?

    <p>Rash</p> Signup and view all the answers

    What type of E.coli is primarily associated with traveler's diarrhea?

    <p>Enterotoxigenic E.coli (ETEC)</p> Signup and view all the answers

    Which strain of E.coli is most commonly associated with severe symptoms, such as hemorrhagic colitis?

    <p>O157:H7</p> Signup and view all the answers

    What is the primary transmission route for intestinal diseases caused by E.coli?

    <p>Fecal/oral route</p> Signup and view all the answers

    Which type of E.coli is particularly dangerous due to its potential to cause hemolytic uremic syndrome (HUS)?

    <p>Enterohemorrhagic E.coli (EHEC)</p> Signup and view all the answers

    What differentiates enteroinvasive E.coli (EIEC) from enterotoxigenic (ETEC) and enteropathogenic (EPEC) E.coli?

    <p>It causes a dysentery-like syndrome.</p> Signup and view all the answers

    In what situation does E.coli become pathogenic in the case of extraintestinal disease?

    <p>When it originates from the patient’s own flora.</p> Signup and view all the answers

    Which group is at a higher risk for urinary tract infections (UTIs) caused by E.coli?

    <p>Women</p> Signup and view all the answers

    What type of E.coli is recognized for causing persistent diarrhea in young children?

    <p>Enteroaggregative E.coli (EAEC)</p> Signup and view all the answers

    Study Notes

    Gram-Negative Bacteria

    • Gram-negative bacteria are a large group of bacteria characterized by their cell wall structure, which distinguishes them from gram-positive bacteria.

    Cocci

    • Neisseria:
      • Diplococci (occur in pairs)
      • Gram-negative
      • Aerobic
      • Pathogenic, causing gonorrhea and meningitis.
      • Gonorrhea is a sexually transmitted disease.
      • Meningitis is an inflammation of the membranes surrounding the brain.

    Bacilli

    • Straight bacilli:
      • Enteric bacteria (e.g., Legionella, Yersinia, Francisella, Pasteurella, Pseudomonas, Acinetobacter)
        • Some cause intestinal and extraintestinal diseases
    • Curved bacilli:
      • Campylobacter, Helicobacter, Vibrio
        • Campylobacter species cause enteritis and sometimes bacteremia.
        • Helicobacter species cause gastritis and peptic ulcers; are linked to stomach cancer.
        • Vibrio species cause cholera, characterized by profuse watery diarrhea.

    Other Gram-Negative Bacteria

    • Moraxella:
      • Nonmotile, gram-negative coccobacilli, usually in pairs
      • Cause infections that include respiratory system, middle ear, eye, CNS, and joints.
    • Acinetobacter:
      • Nonmotile, gram-negative coccobacilli
      • Important nosocomial (hospital-acquired) pathogens.
    • Escherichia coli (E. coli):
      • Part of the normal microbiota of the colon in humans and other animals
      • Can be pathogenic in both the intestinal tract and extra-intestinal sites
    • Enterotoxigenic E. coli (ETEC):
      • A common cause of traveler's diarrhea
      • Transmitted through food, water, and person-to-person contact
    • Enteropathogenic E. coli (EPEC):
      • A significant cause of diarrhea in infants, especially in areas with poor sanitation
    • Enterohemorrhagic E. coli (EHEC):
      • Produces Shiga-like toxin (verotoxin)
      • Causes hemorrhagic colitis with potential for hemolytic uremic syndrome (HUS)
    • Enteroinvasive E. coli (EIEC):
      • Causes a dysentery-like syndrome with bloody stools
    • Enteroaggregative E. coli (EAEC):
      • Causes traveler's diarrhea and persistent diarrhea in young children
    • Urinary tract infections (UTIs):
      • A frequent cause of E. coli infections.
    • Other Gram-negative Rods:
      • Salmonella (gastroenteritis, typhoid fever): food poisoning. -Common cause of food poisoning
      • Shigella (bacillary dysentery): acute gastroenteritis -A common cause of bloody diarrhea -Yersinia (yersiniosis, plague): different diseases in humans; plague can be fatal -Can lead to the potentially fatal plague
      • Legionella (Legionnaire's disease, Pontiac fever): respiratory infections; often transmitted from water sources

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    Description

    Explore the diverse world of gram-negative bacteria, including their unique cell wall structure and classification. This quiz covers important genera such as Neisseria and various bacilli, focusing on their pathogenic roles and associated diseases. Test your knowledge about these significant microorganisms!

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