Graft Rejection Classification
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Questions and Answers

Which type of graft rejection occurs within minutes of transplantation and is characterized by thrombosis of graft vessels and ischemic necrosis of the graft?

  • Hyperacute rejection (correct)
  • Chronic rejection
  • Acute rejection
  • Delayed rejection

    • What type of immune response mediates hyperacute rejection?

  • Circulating antibodies specific for antigens on graft endothelial cells (correct)
  • T cells
  • Natural killer cells
  • B cells

    • Why is hyperacute rejection not a common problem in clinical transplantation?

  • Donor and recipient are matched for blood type (correct)
  • Donor and recipient are matched for gender
  • Donor and recipient are matched for age
  • Donor and recipient are matched for tissue type

    • Which cells are responsible for directly destroying graft cells in acute rejection?

    <p>CD8+ CTLs</p> Signup and view all the answers

    What is the main cause of antibody-mediated injury to graft vessels in acute rejection?

    <p>Complement activation by the classical pathway</p> Signup and view all the answers

    What is the principal cause of graft failure in transplantation?

    <p>Chronic rejection</p> Signup and view all the answers

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