Podcast
Questions and Answers
Which type of graft rejection occurs within minutes of transplantation and is characterized by thrombosis of graft vessels and ischemic necrosis of the graft?
Which type of graft rejection occurs within minutes of transplantation and is characterized by thrombosis of graft vessels and ischemic necrosis of the graft?
- Hyperacute rejection (correct)
- Chronic rejection
- Acute rejection
- Delayed rejection
What type of immune response mediates hyperacute rejection?
What type of immune response mediates hyperacute rejection?
- Circulating antibodies specific for antigens on graft endothelial cells (correct)
- T cells
- Natural killer cells
- B cells
Why is hyperacute rejection not a common problem in clinical transplantation?
Why is hyperacute rejection not a common problem in clinical transplantation?
- Donor and recipient are matched for blood type (correct)
- Donor and recipient are matched for gender
- Donor and recipient are matched for age
- Donor and recipient are matched for tissue type
Which cells are responsible for directly destroying graft cells in acute rejection?
Which cells are responsible for directly destroying graft cells in acute rejection?
What is the main cause of antibody-mediated injury to graft vessels in acute rejection?
What is the main cause of antibody-mediated injury to graft vessels in acute rejection?
What is the principal cause of graft failure in transplantation?
What is the principal cause of graft failure in transplantation?