Graded Dose-Response and Therapeutic Response in Pharmacodynamics
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Questions and Answers

What is the primary purpose of a graded dose-response curve in pharmacodynamics?

  • To quantify the relationship between drug dose and effect (correct)
  • To determine the minimum effective dose of a drug
  • To compare the efficacy of different drugs
  • To predict the therapeutic index of a drug

What is the therapeutic response of a drug?

  • The maximum effect that a drug can produce
  • The minimum dose of a drug that produces a response
  • The response to a drug that results in a therapeutic effect (correct)
  • The dose of a drug that produces a toxic response

What is the difference between a graded dose-response and a quantal dose-response?

  • A graded dose-response is based on the dose of a drug, while a quantal dose-response is based on the concentration of a drug
  • A graded dose-response is linear, while a quantal dose-response is non-linear
  • A graded dose-response is used for in vitro experiments, while a quantal dose-response is used for in vivo experiments
  • A graded dose-response describes the intensity of response, while a quantal dose-response describes the frequency of response (correct)

What is the advantage of using a graded dose-response curve in pharmacodynamics?

<p>It allows for the quantification of the relationship between drug dose and effect (C)</p> Signup and view all the answers

What is the relationship between the dose of a drug and its therapeutic response?

<p>The therapeutic response is directly proportional to the dose of the drug (A)</p> Signup and view all the answers

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