Clinical Testing Duration and Graded Dose Response Relationship Quiz
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Questions and Answers

What is the primary determinant of a drug's selectivity for a particular receptor?

  • Size
  • Affinity for binding (correct)
  • Chemical charge
  • Molecular weight
  • Which type of drug binds to a receptor and activates it, initiating a biological response?

  • Agonist (correct)
  • Inverse agonist
  • Antagonist
  • Allosteric modulator
  • Which class of antagonists competitively inhibits the action of an agonist by binding reversibly to the receptor?

  • Competitive antagonists (correct)
  • Noncompetitive antagonists
  • Orthosteric antagonists
  • Irreversible antagonists
  • Which type of drug bond allows for the greatest selectivity?

    <p>Covalent bonds</p> Signup and view all the answers

    Which neurotransmitter has a weak affinity for nicotine?

    <p>Acetylcholine</p> Signup and view all the answers

    What type of medication would be most appropriate for stimulating bladder emptying in a patient with urinary retention following abdominal surgery?

    <p>Betanechol</p> Signup and view all the answers

    Which drug lacks nicotinic action due to the addition of a methyl group?

    <p>Carbachol</p> Signup and view all the answers

    In narrow-angle glaucoma, which patient presents with this condition?

    <p>A 40-year-old patient with narrow-angle glaucoma</p> Signup and view all the answers

    What is the term used for drugs that have almost exclusively harmful effects?

    <p>Poisons</p> Signup and view all the answers

    Which type of bond in drug-receptor interactions is generally the strongest?

    <p>Covalent bonds</p> Signup and view all the answers

    What did Paracelsus state in relation to drugs?

    <p>Dose makes the poison</p> Signup and view all the answers

    What is the primary reason for the narrow range of molecular weights of most drugs?

    <p>To ensure specificity of action</p> Signup and view all the answers

    What is the duration range for clinical testing mentioned in the text?

    <p>1-6 years</p> Signup and view all the answers

    Which statement about the Graded Dose Response Relationship is NOT true?

    <p>The Emax occurs when all receptors are bound</p> Signup and view all the answers

    Which type of signals are released into the environment and act on different individuals?

    <p>Pheromones</p> Signup and view all the answers

    Which system stimulates and blocks receptors of the autonomic nervous system?

    <p>Adrenergic drugs</p> Signup and view all the answers

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