Gonorrhea Signs and Symptoms Quiz
16 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main function of Neisseria Spp's LOS?

  • Contains endotoxin (correct)
  • Contains IgA proteases
  • Serves as a capsule
  • Acts as an evasin

Which proteins in Neisseria Spp are involved in nutrient/waste exchange and inhibition of phagolysosome fusion in PMNs?

  • Porin Proteins (correct)
  • Opa proteins
  • Lactoferrin-BP
  • Pili

How does Neisseria Meningitidis primarily enter the body?

  • Through blood stream causing bacteremia
  • By attaching to ciliated epithelial cells
  • By penetrating the skin barrier
  • Via the Trojan Horse mechanism through phagocytes (correct)

Which age group is Neisseria Meningitidis endemic in?

<p>Teens and young adults (B)</p> Signup and view all the answers

What is the most common complication of Neisseria Meningitidis infection?

<p>Meningitis (C)</p> Signup and view all the answers

What symptom distinguishes Fulminant meningococcal septicemia caused by Neisseria Meningitidis?

<p>Intraocular hemorrhage (D)</p> Signup and view all the answers

Which age group is Neisseria Gonorrhea mainly transmitted among?

<p>People aged 15-24 years old (C)</p> Signup and view all the answers

Who are the most common asymptomatic carriers/reservoirs of Neisseria Gonorrhea?

<p>Women (B)</p> Signup and view all the answers

Which Streptococcus Pyogenes virulence factor blocks complement by binding fibrinogen?

<p>M-protein (C)</p> Signup and view all the answers

What is the primary function of Streptococcus Pyogenes exotoxin SLO?

<p>Cytolysis of leukocytes (D)</p> Signup and view all the answers

Which Streptococcus Pyogenes virulence factor degrades hyaluronic acid to aid in tissue invasion?

<p>Hyaluronidase (B)</p> Signup and view all the answers

What is the role of Lipoteichoic acid in Streptococcus Pyogenes infections?

<p>Promoting tissue adhesion (D)</p> Signup and view all the answers

Which Streptococcus Pyogenes exotoxin is crucial for diagnosis based on ASO titer measurement?

<p>SPE A (A)</p> Signup and view all the answers

What is the main function of Streptococcus Pyogenes invasin DNAse during infection?

<p>Degradation of extracellular DNA barriers (B)</p> Signup and view all the answers

Which adhesin in Streptococcus Pyogenes is involved in binding to host cell receptors?

<p>FbP (C)</p> Signup and view all the answers

What is the primary function of Streptococcus Pyogenes exotoxin SLS?

<p>Causing leukocyte cytolysis through β-hemolysis (D)</p> Signup and view all the answers

Flashcards

What is LOS in Neisseria spp.?

A component of Neisseria spp. that contains endotoxin, a substance responsible for triggering immune responses and potentially causing inflammation.

How do Porin proteins contribute to Neisseria spp. survival?

Porins are proteins that form channels in the bacterial cell wall, which allows for the exchange of nutrients and waste. Additionally, they impede phagocytosis by preventing the fusion of phagosomes and lysosomes.

How does Neisseria meningitidis infiltrate the body?

Neisseria meningitidis enters the body via phagocytes, specifically by hiding within them, thus evading immune detection.

Who is most susceptible to Neisseria meningitidis infections?

Neisseria meningitidis infections are more common in older adolescents and young adults. This is likely due to factors like close living arrangements, increased social interaction, and less effective immunity.

Signup and view all the flashcards

What is the most prevalent complication of Neisseria meningitidis infection?

Meningitis, an inflammation of the protective membranes surrounding the brain and spinal cord, is the most frequent complication of a Neisseria meningitidis infection.

Signup and view all the flashcards

What is the distinctive symptom of Fulminant meningococcal septicemia?

Fulminant meningococcal septicemia is a severe, rapidly progressing form of Neisseria meningitidis infection, characterized by a hallmark symptom of bleeding in the eyes.

Signup and view all the flashcards

Who is mainly affected by Neisseria gonorrhoeae transmissions?

Neisseria gonorrhoeae transmissions are particularly high among individuals between 15 and 24 years old. This age group often engages in more sexual activity, contributing to higher infection rates.

Signup and view all the flashcards

Who are the usual asymptomatic carriers of Neisseria gonorrhoeae?

Women are more likely to be asymptomatic carriers of Neisseria gonorrhoeae, meaning they can carry the bacteria without exhibiting symptoms but can still transmit it to partners.

Signup and view all the flashcards

How does M-protein in Streptococcus pyogenes affect the complement system?

M-protein on Streptococcus pyogenes binds to fibrinogen, a clotting protein, interfering with the complement system's ability to eliminate bacteria.

Signup and view all the flashcards

What is the function of SLO in Streptococcus pyogenes?

Streptolysin O (SLO) is an exotoxin produced by Streptococcus pyogenes that can lyse (rupture) leukocytes, effectively weakening the host immune system.

Signup and view all the flashcards

What is the role of Hyaluronidase in Streptococcus pyogenes infection?

Hyaluronidase, an enzyme released by Streptococcus pyogenes, breaks down hyaluronic acid, a substance found in connective tissue, facilitating the bacteria's spread through tissues.

Signup and view all the flashcards

What is the purpose of Lipoteichoic acid in Streptococcus pyogenes infections?

Lipoteichoic acid is a surface molecule on Streptococcus pyogenes that helps the bacteria to adhere to host cells, facilitating colonization and potential infection.

Signup and view all the flashcards

How does SPE A aid in Streptococcus pyogenes diagnosis?

Streptococcal pyrogenic exotoxin A (SPE A) is a crucial exotoxin for diagnosis because its levels can be measured using the ASO titer test, helping to detect a Streptococcus pyogenes infection.

Signup and view all the flashcards

What is the purpose of Invasin DNAse in Streptococcus pyogenes?

Streptococcus pyogenes produces a DNAse known as invasin DNAse that degrades extracellular DNA, removing barriers and facilitating the bacteria's movement within tissues.

Signup and view all the flashcards

How does Streptococcus pyogenes bind to host cells?

Fibrinogen-binding protein (FbP) on Streptococcus pyogenes is responsible for attaching to host cell receptors, allowing the bacteria to bind and colonize tissues.

Signup and view all the flashcards

What is the function of Streptococcus pyogenes' SLS?

Streptolysin S (SLS) is an exotoxin produced by Streptococcus pyogenes that causes lysis of leukocytes through beta-hemolysis, resulting in weakening of the host immune response.

Signup and view all the flashcards

Study Notes

  • Adherence in gonorrhea is facilitated by pili, Opa proteins on microvilli and non-ciliated cells, and Por.Major, leading to purulent discharge in infected sites like the urethra, cervix, epididymis, prostate, and anus within 2-5 days.
  • Symptoms of gonorrhea include pyuria, dysuria, pharyngitis from oral sex, and anorectal gonorrhea can cause proctitis.
  • Complications of gonorrhea can include prostatitis, orchitis, pelvic inflammatory diseases like endometriosis, salpingitis, tubo-ovarian abscess, pelvic peritonitis, spontaneous abortion, and early rupture of fetal membranes.
  • Neonatal infections of gonorrhea can result in Ophthalmia Neonatorum with acute conjunctivitis confirmed by lab diagnosis.
  • Moraxella, a normal flora of the upper respiratory tract, can lead to otitis media, sinusitis, and pneumonia in adults, including those with COPD.
  • Neisseria and Moraxella are aerobic, fastidious Gram-negative diplococci, with Neisseria being DNase-, Cat+ and true pathogens, while Moraxella is DNase+, Cat+ and opportunistic pathogens.
  • Treatment for N.gonorrhea includes ceftriaxone + doxycycline, while prophylaxis for neonatal infections involves antibiotics or 1% silver nitrate solution. Neisseria meningitidis is treated with penicillin or cephalosporins, and breastfeeding provides passive immunity.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Description

Test your knowledge on the signs, symptoms, and complications of gonorrhea. Explore how adherence by pili, Opa, and Por.Major contribute to the infection, along with major symptoms such as purulent discharge, pyuria, and dysuria. Learn about various modes of transmission and possible complications like prostatitis, orchitis, and pelvic inflammatory disease.

More Like This

Infections and Symptoms Overview
24 questions
Gonorrhea: Symptoms and Treatments
80 questions
Sexually Transmitted Infections Quiz
48 questions
Use Quizgecko on...
Browser
Browser