Podcast
Questions and Answers
What is the main function of Neisseria Spp's LOS?
What is the main function of Neisseria Spp's LOS?
- Contains endotoxin (correct)
- Contains IgA proteases
- Serves as a capsule
- Acts as an evasin
Which proteins in Neisseria Spp are involved in nutrient/waste exchange and inhibition of phagolysosome fusion in PMNs?
Which proteins in Neisseria Spp are involved in nutrient/waste exchange and inhibition of phagolysosome fusion in PMNs?
- Porin Proteins (correct)
- Opa proteins
- Lactoferrin-BP
- Pili
How does Neisseria Meningitidis primarily enter the body?
How does Neisseria Meningitidis primarily enter the body?
- Through blood stream causing bacteremia
- By attaching to ciliated epithelial cells
- By penetrating the skin barrier
- Via the Trojan Horse mechanism through phagocytes (correct)
Which age group is Neisseria Meningitidis endemic in?
Which age group is Neisseria Meningitidis endemic in?
What is the most common complication of Neisseria Meningitidis infection?
What is the most common complication of Neisseria Meningitidis infection?
What symptom distinguishes Fulminant meningococcal septicemia caused by Neisseria Meningitidis?
What symptom distinguishes Fulminant meningococcal septicemia caused by Neisseria Meningitidis?
Which age group is Neisseria Gonorrhea mainly transmitted among?
Which age group is Neisseria Gonorrhea mainly transmitted among?
Who are the most common asymptomatic carriers/reservoirs of Neisseria Gonorrhea?
Who are the most common asymptomatic carriers/reservoirs of Neisseria Gonorrhea?
Which Streptococcus Pyogenes virulence factor blocks complement by binding fibrinogen?
Which Streptococcus Pyogenes virulence factor blocks complement by binding fibrinogen?
What is the primary function of Streptococcus Pyogenes exotoxin SLO?
What is the primary function of Streptococcus Pyogenes exotoxin SLO?
Which Streptococcus Pyogenes virulence factor degrades hyaluronic acid to aid in tissue invasion?
Which Streptococcus Pyogenes virulence factor degrades hyaluronic acid to aid in tissue invasion?
What is the role of Lipoteichoic acid in Streptococcus Pyogenes infections?
What is the role of Lipoteichoic acid in Streptococcus Pyogenes infections?
Which Streptococcus Pyogenes exotoxin is crucial for diagnosis based on ASO titer measurement?
Which Streptococcus Pyogenes exotoxin is crucial for diagnosis based on ASO titer measurement?
What is the main function of Streptococcus Pyogenes invasin DNAse during infection?
What is the main function of Streptococcus Pyogenes invasin DNAse during infection?
Which adhesin in Streptococcus Pyogenes is involved in binding to host cell receptors?
Which adhesin in Streptococcus Pyogenes is involved in binding to host cell receptors?
What is the primary function of Streptococcus Pyogenes exotoxin SLS?
What is the primary function of Streptococcus Pyogenes exotoxin SLS?
Flashcards
What is LOS in Neisseria spp.?
What is LOS in Neisseria spp.?
A component of Neisseria spp. that contains endotoxin, a substance responsible for triggering immune responses and potentially causing inflammation.
How do Porin proteins contribute to Neisseria spp. survival?
How do Porin proteins contribute to Neisseria spp. survival?
Porins are proteins that form channels in the bacterial cell wall, which allows for the exchange of nutrients and waste. Additionally, they impede phagocytosis by preventing the fusion of phagosomes and lysosomes.
How does Neisseria meningitidis infiltrate the body?
How does Neisseria meningitidis infiltrate the body?
Neisseria meningitidis enters the body via phagocytes, specifically by hiding within them, thus evading immune detection.
Who is most susceptible to Neisseria meningitidis infections?
Who is most susceptible to Neisseria meningitidis infections?
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What is the most prevalent complication of Neisseria meningitidis infection?
What is the most prevalent complication of Neisseria meningitidis infection?
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What is the distinctive symptom of Fulminant meningococcal septicemia?
What is the distinctive symptom of Fulminant meningococcal septicemia?
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Who is mainly affected by Neisseria gonorrhoeae transmissions?
Who is mainly affected by Neisseria gonorrhoeae transmissions?
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Who are the usual asymptomatic carriers of Neisseria gonorrhoeae?
Who are the usual asymptomatic carriers of Neisseria gonorrhoeae?
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How does M-protein in Streptococcus pyogenes affect the complement system?
How does M-protein in Streptococcus pyogenes affect the complement system?
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What is the function of SLO in Streptococcus pyogenes?
What is the function of SLO in Streptococcus pyogenes?
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What is the role of Hyaluronidase in Streptococcus pyogenes infection?
What is the role of Hyaluronidase in Streptococcus pyogenes infection?
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What is the purpose of Lipoteichoic acid in Streptococcus pyogenes infections?
What is the purpose of Lipoteichoic acid in Streptococcus pyogenes infections?
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How does SPE A aid in Streptococcus pyogenes diagnosis?
How does SPE A aid in Streptococcus pyogenes diagnosis?
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What is the purpose of Invasin DNAse in Streptococcus pyogenes?
What is the purpose of Invasin DNAse in Streptococcus pyogenes?
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How does Streptococcus pyogenes bind to host cells?
How does Streptococcus pyogenes bind to host cells?
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What is the function of Streptococcus pyogenes' SLS?
What is the function of Streptococcus pyogenes' SLS?
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Study Notes
- Adherence in gonorrhea is facilitated by pili, Opa proteins on microvilli and non-ciliated cells, and Por.Major, leading to purulent discharge in infected sites like the urethra, cervix, epididymis, prostate, and anus within 2-5 days.
- Symptoms of gonorrhea include pyuria, dysuria, pharyngitis from oral sex, and anorectal gonorrhea can cause proctitis.
- Complications of gonorrhea can include prostatitis, orchitis, pelvic inflammatory diseases like endometriosis, salpingitis, tubo-ovarian abscess, pelvic peritonitis, spontaneous abortion, and early rupture of fetal membranes.
- Neonatal infections of gonorrhea can result in Ophthalmia Neonatorum with acute conjunctivitis confirmed by lab diagnosis.
- Moraxella, a normal flora of the upper respiratory tract, can lead to otitis media, sinusitis, and pneumonia in adults, including those with COPD.
- Neisseria and Moraxella are aerobic, fastidious Gram-negative diplococci, with Neisseria being DNase-, Cat+ and true pathogens, while Moraxella is DNase+, Cat+ and opportunistic pathogens.
- Treatment for N.gonorrhea includes ceftriaxone + doxycycline, while prophylaxis for neonatal infections involves antibiotics or 1% silver nitrate solution. Neisseria meningitidis is treated with penicillin or cephalosporins, and breastfeeding provides passive immunity.
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Description
Test your knowledge on the signs, symptoms, and complications of gonorrhea. Explore how adherence by pili, Opa, and Por.Major contribute to the infection, along with major symptoms such as purulent discharge, pyuria, and dysuria. Learn about various modes of transmission and possible complications like prostatitis, orchitis, and pelvic inflammatory disease.