Gonococci and Meningococci

What is the primary goal of immediate treatment for meningococcal infection?

To prevent septicemia (correct)
To eliminate rash
To reduce fever
To alleviate headache

What is the preferred antibiotic for treating meningococcal infection?

Ampicillin
Penicillin G (correct)
Erythromycin
Tetracycline

What is a characteristic symptom of meningococcal infection?

Rash (correct)
Nausea
Sore throat
Fatigue

Why is prompt treatment of meningococcal infection essential?

To prevent complications (D) Signup and view all the answers

What is the consequence of delayed treatment of meningococcal infection?

Increased risk of septicemia (A) Signup and view all the answers

What is the next stage of DGI, especially in the knee?

Septic arthritis (D) Signup and view all the answers

In which group of people is DGI mostly seen?

Untreated asymptomatic women and persons with complement deficiency (D) Signup and view all the answers

What is the cause of Ophthalmia neonatorum?

Infection acquired during passage through the birth canal of a mother infected with gonococcus (C) Signup and view all the answers

What is the role of the birth canal in Ophthalmia neonatorum?

The birth canal is the route of transmission of the infection (C) Signup and view all the answers

What is the organism responsible for Ophthalmia neonatorum?

Gonococcus (B) Signup and view all the answers

What is the sensitivity of the bacteria to?

Colistin (A) Signup and view all the answers

Which of the following media is not suitable for the growth of the bacteria?

Gonococci selective media (B) Signup and view all the answers

What is the common characteristic of the media on which the bacteria grow?

Absence of selective agents (D) Signup and view all the answers

Why do the bacteria not grow on gonococci selective media?

Due to presence of colistin (D) Signup and view all the answers

What is the characteristic of the media on which the bacteria do not grow?

Presence of selective agents (C) Signup and view all the answers

What is the function of IgA protease produced by gonococci and meningococci?

To cleave IgA1 and help the pathogen evade immunoglobulins (C) Signup and view all the answers

What is a consequence of meningococcal infection?

Spleen, liver, and lymph nodes are enlarged (C) Signup and view all the answers

What is the primary site of colonization for gonococci?

Mucous membrane of the genitourinary tract (C) Signup and view all the answers

What type of immunoglobulin do gonococci and meningococci produce proteases against?

IgA1 (D) Signup and view all the answers

What is the role of O antigen polysaccharides in endotoxin?

They are responsible for the loss of virulence (C) Signup and view all the answers

What is the result of IgA protease activity on IgA1?

Cleavage of IgA1 (A) Signup and view all the answers

What is the effect of the loss of O antigen polysaccharides on the organism?

The organism loses its virulence (A) Signup and view all the answers

Which type of bacteria is known to produce IgA protease?

Gonococci and meningococci (B) Signup and view all the answers

What is the relationship between endotoxin and the pathogenesis of meningococcal infection?

Endotoxin is involved in the pathogenesis (B) Signup and view all the answers

What is the consequence of the modification of endotoxin?

The organism's virulence decreases (A) Signup and view all the answers