25 Questions
What is the primary goal of immediate treatment for meningococcal infection?
To prevent septicemia
What is the preferred antibiotic for treating meningococcal infection?
Penicillin G
What is a characteristic symptom of meningococcal infection?
Rash
Why is prompt treatment of meningococcal infection essential?
To prevent complications
What is the consequence of delayed treatment of meningococcal infection?
Increased risk of septicemia
What is the next stage of DGI, especially in the knee?
Septic arthritis
In which group of people is DGI mostly seen?
Untreated asymptomatic women and persons with complement deficiency
What is the cause of Ophthalmia neonatorum?
Infection acquired during passage through the birth canal of a mother infected with gonococcus
What is the role of the birth canal in Ophthalmia neonatorum?
The birth canal is the route of transmission of the infection
What is the organism responsible for Ophthalmia neonatorum?
Gonococcus
What is the sensitivity of the bacteria to?
Colistin
Which of the following media is not suitable for the growth of the bacteria?
Gonococci selective media
What is the common characteristic of the media on which the bacteria grow?
Absence of selective agents
Why do the bacteria not grow on gonococci selective media?
Due to presence of colistin
What is the characteristic of the media on which the bacteria do not grow?
Presence of selective agents
What is the function of IgA protease produced by gonococci and meningococci?
To cleave IgA1 and help the pathogen evade immunoglobulins
What is a consequence of meningococcal infection?
Spleen, liver, and lymph nodes are enlarged
What is the primary site of colonization for gonococci?
Mucous membrane of the genitourinary tract
What type of immunoglobulin do gonococci and meningococci produce proteases against?
IgA1
What is the role of O antigen polysaccharides in endotoxin?
They are responsible for the loss of virulence
What is the result of IgA protease activity on IgA1?
Cleavage of IgA1
What is the effect of the loss of O antigen polysaccharides on the organism?
The organism loses its virulence
Which type of bacteria is known to produce IgA protease?
Gonococci and meningococci
What is the relationship between endotoxin and the pathogenesis of meningococcal infection?
Endotoxin is involved in the pathogenesis
What is the consequence of the modification of endotoxin?
The organism's virulence decreases
Learn about the characteristics of gonococci and meningococci, including their ability to evade immunoglobulins and colonize the genitourinary tract.
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